| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Avatar | - | - | - | $1,012,529 | 14 | $2,515,341 | Dec 17 | 20th Century Fox International | false |
| 2 | Sex and the City 2 | - | - | - | $336,548 | 9 | $370,160 | Jun 3 | Warner Bros. | false |
| 3 | Skinning | - | - | - | $243,459 | 6 | $288,512 | Oct 7 | - | false |
| 4 | Sherlock Holmes | - | - | - | $222,536 | 6 | $225,430 | Jan 7 | Warner Bros. | false |
| 5 | Alice in Wonderland | - | - | - | $204,356 | 6 | $212,062 | Mar 4 | Walt Disney Pictures | false |
| 6 | Inception | - | - | - | $177,676 | 6 | $183,532 | Jul 22 | Warner Bros. | false |
| 7 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $172,340 | 8 | $238,911 | Nov 18 | Warner Bros. | false |
| 8 | Shrek Forever After | - | - | - | $164,809 | 7 | $167,307 | May 27 | United International Pictures | false |
| 9 | Eat Pray Love | - | - | - | $150,579 | 8 | $158,065 | Oct 21 | Sony Pictures Releasing | false |
| 10 | Robin Hood | - | - | - | $149,341 | 7 | $161,619 | May 13 | United International Pictures | false |
| 11 | Clash of the Titans | - | - | - | $147,593 | 10 | $158,605 | Apr 8 | Warner Bros. | false |
| 12 | Prince of Persia: The Sands of Time | - | - | - | $144,514 | 6 | $154,832 | Jun 3 | Walt Disney Pictures | false |
| 13 | Valentine's Day | - | - | - | $121,215 | 6 | $131,583 | Feb 11 | Warner Bros. | false |
| 14 | The Expendables | - | - | - | $117,874 | 5 | $127,083 | Aug 26 | - | false |
| 15 | The Woman with a Broken Nose | - | - | - | $100,716 | 6 | $113,631 | Sep 2 | - | false |
| 16 | Did You Hear About the Morgans? | - | - | - | $87,864 | 7 | $87,864 | Jan 21 | Sony Pictures Releasing | false |
| 17 | The Wolfman | - | - | - | $86,781 | 6 | $89,919 | Feb 25 | United International Pictures | false |
| 18 | The Twilight Saga: Eclipse | - | - | - | $84,410 | 5 | $101,853 | Jul 1 | - | false |
| 19 | Due Date | - | - | - | $81,486 | 6 | $127,159 | Dec 2 | Warner Bros. | false |
| 20 | Killers | - | - | - | $80,015 | 3 | $83,750 | Jul 8 | - | false |
| 21 | It's Complicated | - | - | - | $79,752 | 9 | $114,556 | Dec 24 | United International Pictures | false |
| 22 | Shutter Island | - | - | - | $78,881 | 4 | $105,693 | Mar 11 | United International Pictures | false |
| 23 | Salt | - | - | - | $74,083 | 7 | $74,083 | Aug 5 | Sony Pictures Releasing | false |
| 24 | The Princess and the Frog | - | - | - | $70,636 | 6 | $74,148 | Jan 28 | Walt Disney Pictures | false |
| 25 | Old Dogs | - | - | - | $70,192 | 5 | $73,523 | Jan 14 | Walt Disney Pictures | false |
| 26 | Toy Story 3 | - | - | - | $69,421 | 7 | $71,404 | Jun 17 | Walt Disney Pictures | false |
| 27 | The Town | - | - | - | $66,461 | 4 | $74,966 | Nov 4 | Warner Bros. | false |
| 28 | Arthur and the Revenge of Maltazard | - | - | - | $66,127 | 6 | $67,334 | Dec 31 | - | false |
| 29 | Grown Ups | - | - | - | $65,618 | 7 | $65,618 | Sep 9 | Sony Pictures Releasing | false |
| 30 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $65,262 | 7 | $66,312 | Jan 14 | 20th Century Fox International | false |
| 31 | The Bounty Hunter | - | - | - | $62,846 | 6 | $62,846 | Apr 22 | Sony Pictures Releasing | false |
| 32 | How to Train Your Dragon | - | - | - | $61,926 | 7 | $64,614 | Apr 15 | United International Pictures | false |
| 33 | A Nightmare on Elm Street | - | - | - | $59,736 | 6 | $61,670 | Jun 17 | Warner Bros. | false |
| 34 | Resident Evil: Afterlife | - | - | - | $58,686 | 8 | $58,686 | Sep 23 | Sony Pictures Releasing | false |
| 35 | The Back-up Plan | - | - | - | $58,266 | 7 | $58,882 | Jun 17 | Sony Pictures Releasing | false |
| 36 | The Sorcerer's Apprentice | - | - | - | $50,240 | 4 | $52,660 | Jul 15 | United International Pictures | false |
| 37 | The Last Airbender | - | - | - | $47,922 | 6 | $51,923 | Aug 19 | United International Pictures | false |
| 38 | The Social Network | - | - | - | $46,514 | 7 | $55,090 | Nov 4 | Sony Pictures Releasing | false |
| 39 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $45,012 | 8 | $90,216 | Dec 9 | 20th Century Fox International | false |
| 40 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $43,479 | 7 | $44,454 | Feb 25 | 20th Century Fox International | false |
| 41 | Up in the Air | - | - | - | $42,679 | 5 | $45,964 | Feb 4 | United International Pictures | false |
| 42 | Little Fockers | - | - | - | $41,436 | 6 | $164,556 | Dec 23 | United International Pictures | false |
| 43 | Despicable Me | - | - | - | $41,220 | 6 | $42,390 | Sep 9 | United International Pictures | false |
| 44 | The Book of Eli | - | - | - | $40,582 | 6 | $40,582 | Mar 18 | Sony Pictures Releasing | false |
| 45 | Besa | - | - | - | $39,977 | 5 | $40,563 | Apr 1 | - | false |
| 46 | Iron Man 2 | - | - | - | $39,384 | 4 | $41,653 | Apr 29 | Walt Disney Pictures | false |
| 47 | RED | - | - | - | $34,536 | 4 | $46,340 | Nov 4 | - | false |
| 48 | OceanWorld | - | - | - | $33,794 | 1 | $34,786 | Apr 8 | - | false |
| 49 | The Ghost Writer | - | - | - | $33,662 | 3 | $57,819 | May 20 | - | false |
| 50 | The Other Guys | - | - | - | $33,642 | 7 | $33,642 | Oct 14 | Sony Pictures Releasing | false |
| 51 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $33,249 | 9 | $34,914 | Aug 5 | Warner Bros. | false |
| 52 | Going the Distance | - | - | - | $33,236 | 6 | $34,907 | Sep 30 | Warner Bros. | false |
| 53 | Magic Journey to Africa | - | - | - | $32,548 | 3 | $39,751 | Oct 21 | - | false |
| 54 | Machete | - | - | - | $32,155 | 3 | $32,993 | Sep 16 | - | false |
| 55 | Nine | - | - | - | $31,740 | 4 | $31,740 | Feb 4 | - | false |
| 56 | Arthur 3: The War of the Two Worlds | - | - | - | $31,382 | 5 | $36,861 | Oct 28 | - | false |
| 57 | When in Rome | - | - | - | $30,550 | 3 | $32,204 | Apr 8 | United International Pictures | false |
| 58 | Knight and Day 2010 Re-release | - | - | - | $30,527 | 7 | $36,257 | Jul 29 | 20th Century Fox International | false |
| 59 | Toy Story 2009 Re-release | - | - | - | $29,749 | 3 | $29,830 | Feb 11 | Walt Disney Pictures | false |
| 60 | Predators | - | - | - | $29,740 | 7 | $32,105 | Aug 12 | 20th Century Fox International | false |
| 61 | Stone | - | - | - | $28,717 | 2 | $37,585 | Nov 11 | - | false |
| 62 | The Karate Kid | - | - | - | $28,492 | 7 | $33,290 | Sep 2 | Sony Pictures Releasing | false |
| 63 | The Lovely Bones | - | - | - | $28,101 | 5 | $28,101 | Feb 18 | United International Pictures | false |
| 64 | Paranormal Activity 2 | - | - | - | $26,683 | 3 | $39,425 | Dec 2 | - | false |
| 65 | Letters to Juliet | - | - | - | $26,641 | 4 | $27,587 | Aug 19 | - | false |
| 66 | Date Night | - | - | - | $25,527 | 7 | $26,788 | May 20 | 20th Century Fox International | false |
| 67 | The Rebound | - | - | - | $25,206 | 5 | $25,827 | Mar 25 | - | false |
| 68 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $24,303 | 8 | $25,132 | Oct 14 | Warner Bros. | false |
| 69 | Devil | - | - | - | $24,043 | 3 | $27,436 | Nov 4 | United International Pictures | false |
| 70 | Edge of Darkness | - | - | - | $23,775 | 5 | $24,808 | Mar 25 | - | false |
| 71 | The Men Who Stare at Goats | - | - | - | $22,125 | 4 | $28,811 | Mar 11 | - | false |
| 72 | Step Up 3D | - | - | - | $20,040 | 9 | $20,040 | Sep 30 | - | false |
| 73 | 2012 | - | - | - | $19,979 | 10 | $275,735 | Nov 12 | Sony Pictures Releasing | false |
| 74 | Remember Me | - | - | - | $18,809 | 4 | $20,167 | Apr 29 | - | false |
| 75 | The Switch | - | - | - | $18,694 | 4 | $30,820 | Nov 11 | - | false |
| 76 | The Imaginarium of Doctor Parnassus | - | - | - | $18,074 | 2 | $40,269 | Feb 11 | - | false |
| 77 | Law Abiding Citizen | - | - | - | $17,180 | 5 | $21,334 | Feb 18 | - | false |
| 78 | Legion | - | - | - | $15,096 | 5 | $15,096 | Apr 1 | Sony Pictures Releasing | false |
| 79 | Nanny McPhee Returns | - | - | - | $15,087 | 5 | $15,298 | May 13 | United International Pictures | false |
| 80 | Megamind | - | - | - | $14,930 | 7 | $34,023 | Dec 16 | United International Pictures | false |
| 81 | Let Me In | - | - | - | $14,181 | 1 | $17,049 | Nov 18 | - | false |
| 82 | Paranormal Activity | - | - | - | $14,014 | 5 | $56,508 | Nov 26 | - | false |
| 83 | Leap Year | - | - | - | $13,739 | 3 | $14,152 | May 6 | United International Pictures | false |
| 84 | Get Him to the Greek | - | - | - | $13,581 | 4 | $14,659 | Jul 22 | United International Pictures | false |
| 85 | Don't Look Back | - | - | - | $13,487 | 2 | $13,544 | Feb 25 | - | false |
| 86 | Invictus 2010 Re-release | - | - | - | $12,164 | 4 | $26,096 | Mar 4 | Warner Bros. | false |
| 87 | Charlie St. Cloud | - | - | - | $11,599 | 5 | $12,239 | Sep 16 | United International Pictures | false |
| 88 | Planet 51 | - | - | - | $11,120 | 7 | $38,221 | Dec 3 | - | false |
| 89 | From Paris with Love | - | - | - | $10,945 | 5 | $10,945 | Apr 15 | - | false |
| 90 | When You're Strange | - | - | - | $10,807 | 1 | $11,453 | Jul 29 | - | false |
| 91 | Garfield's Fun Fest | - | - | - | $10,691 | 2 | $14,361 | Dec 24 | - | false |
| 92 | The Box | - | - | - | $10,006 | 2 | $10,217 | Jan 14 | - | false |
| 93 | The Killer Inside Me | - | - | - | $9,759 | 1 | $10,105 | Sep 16 | - | false |
| 94 | The A-Team | - | - | - | $9,621 | 6 | $10,636 | Jul 8 | 20th Century Fox International | false |
| 95 | Toy Story 2 2009 Re-release | - | - | - | $8,491 | 3 | $8,642 | Apr 1 | Walt Disney Pictures | false |
| 96 | The Twilight Saga: New Moon | - | - | - | $8,197 | 5 | $107,146 | Dec 3 | - | false |
| 97 | A Christmas Carol | - | - | - | $7,995 | 6 | $73,436 | Nov 19 | Walt Disney Pictures | false |
| 98 | Couples Retreat | - | - | - | $6,408 | 7 | $109,958 | Nov 12 | United International Pictures | false |
| 99 | Kick-Ass | - | - | - | $6,290 | 5 | $6,290 | Jun 10 | - | false |
| 100 | Bad Lieutenant: Port of Call New Orleans | - | - | - | $6,128 | 1 | $18,933 | Apr 29 | - | false |
| 101 | Julie & Julia | - | - | - | $5,948 | 3 | $25,398 | Nov 20 | Sony Pictures Releasing | false |
| 102 | Paintball | - | - | - | $5,267 | 1 | $5,598 | Jun 24 | - | false |
| 103 | Zombieland | - | - | - | $4,745 | 7 | $32,721 | Nov 26 | Sony Pictures Releasing | false |
| 104 | Gamer | - | - | - | $4,730 | 2 | $10,076 | Dec 3 | - | false |
| 105 | Blue Train | - | - | - | $4,588 | 3 | $8,151 | Nov 18 | - | false |
| 106 | The Flight Before Christmas | - | - | - | $4,352 | 3 | $13,131 | Dec 10 | - | false |
| 107 | Pope Joan | - | - | - | $4,024 | 2 | $9,871 | Mar 4 | - | false |
| 108 | Drag Me to Hell | - | - | - | $3,741 | 2 | $11,470 | Nov 19 | - | false |
| 109 | Brothers | - | - | - | $3,713 | 3 | $9,564 | Apr 15 | - | false |
| 110 | The Hurt Locker | - | - | - | $3,635 | 1 | $5,438 | Apr 15 | - | false |
| 111 | Daybreakers | - | - | - | $3,327 | 5 | $3,523 | Mar 11 | - | false |
| 112 | Love Happens | - | - | - | $2,990 | 3 | $22,134 | Nov 19 | - | false |
| 113 | Antichrist | - | - | - | $2,876 | 1 | $13,224 | Mar 4 | - | false |
| 114 | The Road | - | - | - | $2,762 | 1 | $4,537 | Nov 11 | - | false |
| 115 | The Spy Next Door 2010 Re-release | - | - | - | $2,526 | 1 | $2,526 | Jun 24 | - | false |
| 116 | Broken Embraces | - | - | - | $2,408 | 5 | $37,972 | Nov 5 | - | false |
| 117 | The White Ribbon | - | - | - | $2,298 | 1 | $13,277 | Feb 18 | - | false |
| 118 | My Bloody Valentine | - | - | - | $2,254 | 3 | $2,254 | May 6 | - | false |
| 119 | The Countess | - | - | - | $2,095 | 1 | $5,379 | Jan 14 | - | false |
| 120 | Pet Pals: Marco Polo's Code | - | - | - | $1,692 | 4 | $2,758 | Oct 28 | - | false |
| 121 | A Serious Man | - | - | - | $1,647 | 1 | $15,937 | Mar 25 | - | false |
| 122 | Baaria | - | - | - | $1,644 | 1 | $15,338 | Mar 11 | - | false |
| 123 | The Fourth Kind | - | - | - | $1,474 | 1 | $1,694 | Jul 15 | - | false |
| 124 | Coco Chanel & Igor Stravinsky | - | - | - | $1,209 | 2 | $17,734 | Mar 4 | - | false |
| 125 | Babies | - | - | - | $1,193 | 2 | $1,211 | Jun 17 | - | false |
| 126 | North Face | - | - | - | $1,184 | 2 | $2,013 | Dec 17 | - | false |
| 127 | A Woman, a Gun and a Noodle Shop | - | - | - | $1,072 | 1 | $3,270 | Dec 9 | - | false |
| 128 | Mother and Child | - | - | - | $1,071 | 1 | $3,317 | Nov 11 | - | false |
| 129 | My Life in Ruins | - | - | - | $935 | 5 | $47,078 | Nov 5 | - | false |
| 130 | Fish Tank | - | - | - | $864 | 1 | $11,687 | May 6 | - | false |
| 131 | Sunny et l'éléphant 2010 Re-release | - | - | - | $766 | 2 | $1,020 | Oct 28 | - | false |
| 132 | Moomins and the Comet Chase | - | - | - | $694 | 2 | $14,108 | Dec 23 | - | false |
| 133 | Cloudy with a Chance of Meatballs | - | - | - | $601 | 7 | $34,020 | Oct 22 | Sony Pictures Releasing | false |
| 134 | Red Cliff | - | - | - | $545 | 1 | $6,188 | Nov 19 | - | false |
| 135 | Triage | - | - | - | $420 | 2 | $1,450 | Apr 8 | - | false |
| 136 | Centurion | - | - | - | $326 | 1 | $2,188 | Nov 11 | - | false |
| 137 | The Ambulance | - | - | - | $195 | 4 | $4,829 | Nov 26 | - | false |
| 138 | Surrogates | - | - | - | $24 | 4 | $41,702 | Oct 29 | Walt Disney Pictures | false |
| 139 | Wait for Me and I Will Not Come | - | - | - | $6 | 7 | $107,289 | Oct 15 | - | false |
