| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Toy Story 3 | - | - | - | $10,637,930 | 254 | $10,637,930 | Jun 18 | Walt Disney Pictures | false |
| 2 | Avatar | - | - | - | $9,817,160 | 218 | $13,189,735 | Dec 18 | 20th Century Fox International | false |
| 3 | Alice in Wonderland | - | - | - | $6,768,771 | 172 | $6,768,771 | Mar 5 | Walt Disney Pictures | false |
| 4 | Shrek Forever After | - | - | - | $6,688,109 | 179 | $6,688,109 | Jul 9 | United International Pictures | false |
| 5 | Clash of the Titans | - | - | - | $5,548,400 | 186 | $5,548,400 | Apr 16 | Warner Bros. | false |
| 6 | Prince of Persia: The Sands of Time | - | - | - | $3,821,294 | 194 | $3,872,425 | May 28 | Walt Disney Pictures | false |
| 7 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $3,778,249 | 239 | $4,141,436 | Nov 19 | Warner Bros. | false |
| 8 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $3,761,603 | 242 | $4,493,123 | Dec 10 | 20th Century Fox International | false |
| 9 | The Last Airbender | - | - | - | $3,406,396 | 185 | $3,408,130 | Aug 27 | United International Pictures | false |
| 10 | Inception | - | - | - | $3,144,672 | 138 | $3,144,672 | Aug 6 | Warner Bros. | false |
| 11 | Resident Evil: Afterlife | - | - | - | $3,124,133 | 130 | $3,124,133 | Sep 10 | Sony Pictures Releasing | false |
| 12 | The Twilight Saga: Eclipse | - | - | - | $3,041,963 | 212 | $3,042,308 | Jun 30 | Cine Colombia | false |
| 13 | The Sorcerer's Apprentice | - | - | - | $2,950,378 | 116 | $2,953,007 | Jul 16 | Walt Disney Pictures | false |
| 14 | Despicable Me | - | - | - | $2,751,755 | 145 | $297 | Apr 27 | Universal Pictures International (UPI) | false |
| 15 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $2,259,877 | 162 | $2,259,877 | Oct 1 | Warner Bros. | false |
| 16 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $2,094,843 | 146 | $2,094,843 | Aug 13 | Warner Bros. | false |
| 17 | Saw 3D | - | - | - | $1,970,493 | 105 | $1,991,350 | Nov 5 | Cineplex | false |
| 18 | How to Train Your Dragon | - | - | - | $1,917,924 | 115 | $1,917,924 | Mar 26 | United International Pictures | false |
| 19 | Megamind | - | - | - | $1,797,967 | 181 | $2,400,191 | Dec 3 | United International Pictures | false |
| 20 | Sherlock Holmes | - | - | - | $1,657,788 | 109 | $1,657,788 | Jan 8 | Warner Bros. | false |
| 21 | The Karate Kid | - | - | - | $1,559,943 | 80 | $1,559,943 | Jun 18 | Sony Pictures Releasing | false |
| 22 | Paranormal Activity 2 | - | - | - | $1,490,009 | 73 | $1,513,758 | Oct 29 | United International Pictures | false |
| 23 | A Nightmare on Elm Street | - | - | - | $1,406,599 | 94 | $1,406,599 | May 14 | Warner Bros. | false |
| 24 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $1,398,967 | 100 | $1,398,967 | Jan 1 | 20th Century Fox International | false |
| 25 | Robin Hood | - | - | - | $1,329,717 | 128 | $1,329,717 | May 14 | United International Pictures | false |
| 26 | Iron Man 2 | - | - | - | $1,275,996 | 109 | $1,275,996 | Apr 30 | United International Pictures | false |
| 27 | Paranormal Activity | - | - | - | $1,261,145 | 88 | $1,261,145 | Jan 1 | Cine Colombia | false |
| 28 | The Princess and the Frog | - | - | - | $1,184,114 | 133 | $1,872,829 | Dec 25 | Walt Disney Pictures | false |
| 29 | TRON: Legacy | - | - | - | $1,181,548 | 182 | $2,621,248 | Dec 24 | Walt Disney Pictures | false |
| 30 | Old Dogs | - | - | - | $1,163,994 | 51 | $1,163,994 | Jan 8 | Walt Disney Pictures | false |
| 31 | Tooth Fairy | - | - | - | $1,115,668 | 55 | $1,115,668 | Jan 22 | 20th Century Fox International | false |
| 32 | Gulliver's Travels | - | - | - | $1,067,627 | 162 | $2,423,189 | Dec 24 | 20th Century Fox International | false |
| 33 | The Wolfman | - | - | - | $1,044,226 | 96 | $1,045,872 | Feb 12 | United International Pictures | false |
| 34 | The Book of Eli | - | - | - | $1,010,996 | 75 | $1,010,996 | Mar 19 | Sony Pictures Releasing | false |
| 35 | Grown Ups | - | - | - | $998,569 | 50 | $998,569 | Aug 6 | Sony Pictures Releasing | false |
| 36 | Eat Pray Love | - | - | - | $972,593 | 25 | $972,593 | Oct 1 | Sony Pictures Releasing | false |
| 37 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $869,135 | 89 | $869,135 | Feb 12 | 20th Century Fox International | false |
| 38 | The A-Team | - | - | - | $825,969 | 94 | $825,969 | Jun 11 | 20th Century Fox International | false |
| 39 | Marmaduke | - | - | - | $824,212 | 106 | $824,212 | Jun 4 | 20th Century Fox International | false |
| 40 | Salt | - | - | - | $823,455 | 65 | $823,455 | Jul 23 | Sony Pictures Releasing | false |
| 41 | Piranha 3D | - | - | - | $716,661 | 94 | $716,661 | Oct 22 | Cineplex | false |
| 42 | Knight and Day 2010 Re-release | - | - | - | $681,926 | 98 | $714,396 | Jul 16 | 20th Century Fox International | false |
| 43 | Due Date | - | - | - | $631,596 | 70 | $639,569 | Nov 5 | Warner Bros. | false |
| 44 | Legion | - | - | - | $625,699 | 50 | $625,699 | Apr 9 | Sony Pictures Releasing | false |
| 45 | Oceans | - | - | - | $548,608 | 37 | $548,608 | Aug 20 | Cine Colombia | false |
| 46 | Life as We Know It | - | - | - | $542,084 | 44 | $542,084 | Oct 29 | Warner Bros. | false |
| 47 | Shutter Island | - | - | - | $532,767 | 33 | $532,767 | Mar 12 | United International Pictures | false |
| 48 | The Social Network | - | - | - | $519,445 | 35 | $636,335 | Nov 26 | Sony Pictures Releasing | false |
| 49 | Predators | - | - | - | $515,270 | 62 | $515,270 | Aug 13 | 20th Century Fox International | false |
| 50 | The Bounty Hunter | - | - | - | $496,849 | 60 | $496,849 | May 7 | Sony Pictures Releasing | false |
| 51 | Tinker Bell and the Great Fairy Rescue | - | - | - | $468,218 | 42 | $468,218 | Oct 8 | Walt Disney Pictures | false |
| 52 | Wall Street: Money Never Sleeps | - | - | - | $464,834 | 47 | $464,834 | Sep 24 | 20th Century Fox International | false |
| 53 | Edge of Darkness | - | - | - | $448,286 | 58 | $448,286 | Mar 12 | Warner Bros. | false |
| 54 | The Town | - | - | - | $419,746 | 47 | $419,746 | Oct 15 | Warner Bros. | false |
| 55 | Invictus | - | - | - | $400,498 | 46 | $400,498 | Feb 5 | Warner Bros. | false |
| 56 | Valentine's Day | - | - | - | $397,455 | 42 | $397,455 | Feb 12 | Warner Bros. | false |
| 57 | The Blind Side | - | - | - | $382,314 | 47 | $382,314 | Mar 26 | Warner Bros. | false |
| 58 | The Back-up Plan | - | - | - | $378,155 | 40 | $378,155 | Jun 18 | Sony Pictures Releasing | false |
| 59 | Sex and the City 2 | - | - | - | $357,038 | 61 | $357,038 | Jun 4 | Warner Bros. | false |
| 60 | The Girl with the Dragon Tattoo | - | - | - | $333,553 | 70 | $333,553 | Apr 30 | Cine Colombia | false |
| 61 | Devil | - | - | - | $325,588 | 44 | $326,586 | Nov 12 | United International Pictures | false |
| 62 | Precious | - | - | - | $307,036 | 20 | $307,036 | Feb 19 | Cine Colombia | false |
| 63 | Going the Distance | - | - | - | $305,525 | 40 | $305,525 | Sep 17 | Warner Bros. | false |
| 64 | It's Complicated | - | - | - | $290,615 | 50 | $290,615 | Apr 16 | United International Pictures | false |
| 65 | The Collector | - | - | - | $283,518 | 27 | $283,518 | Oct 15 | Venus | false |
| 66 | Did You Hear About the Morgans? | - | - | - | $280,784 | 50 | $280,784 | Mar 26 | Sony Pictures Releasing | false |
| 67 | Law Abiding Citizen | - | - | - | $280,414 | 54 | $280,414 | Feb 26 | Cineplex | false |
| 68 | The Hurt Locker | - | - | - | $272,651 | 13 | $272,651 | Feb 12 | Cineplex | false |
| 69 | Up in the Air | - | - | - | $251,463 | 18 | $251,463 | Jan 22 | United International Pictures | false |
| 70 | [Rec]² | - | - | - | $248,981 | 32 | $248,981 | Mar 5 | Cine Colombia | false |
| 71 | Vampires Suck | - | - | - | $246,857 | 21 | $246,857 | Sep 3 | 20th Century Fox International | false |
| 72 | Couples Retreat | - | - | - | $227,269 | 27 | $227,269 | Feb 26 | United International Pictures | false |
| 73 | Toy Story 2 2009 Re-release | - | - | - | $219,923 | 36 | $219,923 | Feb 26 | Walt Disney Pictures | false |
| 74 | The Other Guys | - | - | - | $195,482 | 40 | $198,902 | Nov 12 | Sony Pictures Releasing | false |
| 75 | Cell 211 | - | - | - | $183,587 | 31 | $183,587 | Apr 16 | Cineplex | false |
| 76 | From Paris with Love | - | - | - | $173,997 | 28 | $173,997 | Sep 17 | - | false |
| 77 | Nanny McPhee Returns | - | - | - | $170,857 | 33 | $170,857 | Jun 11 | United International Pictures | false |
| 78 | Remember Me | - | - | - | $166,540 | 30 | $166,540 | Mar 26 | Cine Colombia | false |
| 79 | Zombieland | - | - | - | $165,261 | 35 | $165,261 | Jan 15 | Sony Pictures Releasing | false |
| 80 | Toy Story 2009 Re-release | - | - | - | $162,111 | 37 | $162,111 | Feb 19 | Walt Disney Pictures | false |
| 81 | Takers 2010 Re-release | - | - | - | $155,748 | 30 | $155,748 | Oct 15 | Sony Pictures Releasing | false |
| 82 | Case 39 | - | - | - | $154,747 | 37 | $154,747 | Apr 9 | United International Pictures | false |
| 83 | Battle for Terra | - | - | - | $148,922 | 35 | $148,922 | May 28 | Cine Colombia | false |
| 84 | Ninja Assassin | - | - | - | $146,524 | 32 | $146,524 | Jan 29 | Warner Bros. | false |
| 85 | Cirque du Freak: The Vampire's Assistant | - | - | - | $138,242 | 38 | $138,242 | Feb 19 | United International Pictures | false |
| 86 | The Box | - | - | - | $137,384 | 23 | $137,384 | Sep 17 | Cine Colombia | false |
| 87 | Daybreakers | - | - | - | $132,270 | 33 | $132,270 | Sep 3 | Venus | false |
| 88 | Green Zone 2010 Re-release | - | - | - | $131,978 | 25 | $131,978 | Aug 20 | United International Pictures | false |
| 89 | The Wave | - | - | - | $129,199 | 8 | $129,199 | Apr 23 | Cine Colombia | false |
| 90 | Nine | - | - | - | $124,753 | 9 | $124,753 | Jan 29 | Sony Pictures Releasing | false |
| 91 | Cherry Blossoms | - | - | - | $123,621 | 7 | $123,621 | Jul 9 | Cine Colombia | false |
| 92 | Halloween II | - | - | - | $118,926 | 22 | $118,926 | Aug 27 | Cine Colombia | false |
| 93 | Buried | - | - | - | $117,563 | 38 | $117,563 | Nov 12 | Walt Disney Pictures | false |
| 94 | The Fourth Kind | - | - | - | $116,160 | 56 | $116,160 | May 14 | Venus | false |
| 95 | Departures | - | - | - | $113,923 | 5 | $113,923 | Jan 15 | Cine Colombia | false |
| 96 | The Lovely Bones | - | - | - | $109,827 | 26 | $109,827 | Feb 19 | United International Pictures | false |
| 97 | Broken Embraces | - | - | - | $104,357 | 20 | $104,357 | Feb 5 | United International Pictures | false |
| 98 | Killers | - | - | - | $99,421 | 25 | $99,421 | Nov 26 | Cineplex | false |
| 99 | Rage | - | - | - | $86,922 | 25 | $86,988 | Nov 5 | Cine Colombia | false |
| 100 | Astro Boy | - | - | - | $77,549 | 27 | $77,549 | Jan 15 | Cine Colombia | false |
| 101 | Dear John | - | - | - | $75,910 | 30 | $75,910 | Apr 23 | Sony Pictures Releasing | false |
| 102 | 2012 | - | - | - | $71,798 | 120 | $4,154,198 | Nov 13 | Sony Pictures Releasing | false |
| 103 | Carriers | - | - | - | $70,668 | 42 | $70,668 | May 21 | Cine Colombia | false |
| 104 | The Spy Next Door 2010 Re-release | - | - | - | $70,271 | 13 | $70,271 | Jul 2 | Cineplex | false |
| 105 | The Soloist | - | - | - | $68,737 | 6 | $68,737 | Jan 15 | United International Pictures | false |
| 106 | The Burning Plain | - | - | - | $68,252 | 10 | $68,252 | Sep 17 | Cine Colombia | false |
| 107 | The Imaginarium of Doctor Parnassus | - | - | - | $65,367 | 9 | $65,367 | Mar 5 | Sony Pictures Releasing | false |
| 108 | Everybody's Fine | - | - | - | $64,836 | 17 | $64,836 | Mar 12 | Walt Disney Pictures | false |
| 109 | Machete | - | - | - | $62,317 | 30 | $62,317 | Dec 3 | Sony Pictures Releasing | false |
| 110 | The Last Song | - | - | - | $57,911 | 16 | $57,911 | Apr 30 | Walt Disney Pictures | false |
| 111 | An Education | - | - | - | $57,596 | 6 | $57,596 | Feb 19 | Sony Pictures Releasing | false |
| 112 | Two Lovers | - | - | - | $55,980 | 13 | $55,980 | Jun 11 | Cine Colombia | false |
| 113 | The Children of Huang Shi | - | - | - | $54,934 | 6 | $55,554 | May 28 | Cine Colombia | false |
| 114 | Mongol: The Rise of Genghis Khan | - | - | - | $54,576 | 9 | $54,576 | Apr 9 | Cine Colombia | false |
| 115 | Micmacs | - | - | - | $53,297 | 10 | $53,297 | Oct 8 | Sony Pictures Releasing | false |
| 116 | Eden Lake | - | - | - | $51,991 | 22 | $99,461 | Jul 23 | Cine Colombia | false |
| 117 | A Single Man | - | - | - | $51,644 | 11 | $51,644 | Oct 29 | - | false |
| 118 | Me Too | - | - | - | $50,998 | 11 | $51,727 | May 14 | Cineplex | false |
| 119 | Gamer | - | - | - | $44,508 | 18 | $44,508 | Apr 30 | Cineplex | false |
| 120 | London River 2010 Re-release | - | - | - | $42,320 | 6 | $64,891 | Nov 19 | - | false |
| 121 | My Life in Ruins | - | - | - | $41,259 | 20 | $41,259 | Jul 30 | Cine Colombia | false |
| 122 | Seraphine | - | - | - | $37,309 | 10 | $37,309 | Apr 30 | Cineplex | false |
| 123 | The White Ribbon | - | - | - | $34,799 | 6 | $34,799 | Mar 5 | - | false |
| 124 | The Twilight Saga: New Moon | - | - | - | $34,034 | 201 | $2,229,922 | Nov 27 | Cine Colombia | false |
| 125 | The Stepfather | - | - | - | $33,436 | 20 | $99,192 | Dec 11 | Sony Pictures Releasing | false |
| 126 | Let the Right One In | - | - | - | $29,997 | 10 | $29,997 | Apr 23 | Cine Colombia | false |
| 127 | The Anarchist's Wife | - | - | - | $28,707 | 4 | $28,707 | Mar 26 | Cineplex | false |
| 128 | I Hate Valentine's Day | - | - | - | $26,671 | 15 | $27,572 | May 28 | Cine Colombia | false |
| 129 | Horn of Plenty 2010 Re-release | - | - | - | $26,064 | 16 | $26,064 | Sep 3 | Cineplex | false |
| 130 | Flame & Citron | - | - | - | $23,992 | 5 | $24,732 | Jan 1 | Cineplex | false |
| 131 | Kick-Ass | - | - | - | $20,361 | 32 | $20,361 | Aug 13 | United International Pictures | false |
| 132 | A Prophet | - | - | - | $19,529 | 3 | $19,529 | Mar 19 | Sony Pictures Releasing | false |
| 133 | A Christmas Tale | - | - | - | $16,214 | 4 | $26,001 | Dec 25 | - | false |
| 134 | Smother | - | - | - | $13,483 | 10 | $13,483 | Apr 16 | Cine Colombia | false |
| 135 | Fame | - | - | - | $13,218 | 15 | $13,218 | Feb 26 | Cine Colombia | false |
| 136 | Pandorum | - | - | - | $13,164 | 18 | $13,164 | May 21 | Cineplex | false |
| 137 | The Men Who Stare at Goats | - | - | - | $13,109 | 3 | $13,109 | Mar 12 | Sony Pictures Releasing | false |
| 138 | LOL (Laughing Out Loud) | - | - | - | $12,919 | 4 | $12,919 | Dec 10 | Cineplex | false |
| 139 | A Serious Man | - | - | - | $12,595 | 5 | $12,595 | Mar 19 | United International Pictures | false |
| 140 | City of Life and Death | - | - | - | $11,196 | 3 | $11,196 | Oct 1 | Cineplex | false |
| 141 | Away We Go | - | - | - | $10,936 | 5 | $10,936 | Apr 9 | United International Pictures | false |
| 142 | Inglourious Basterds | - | - | - | $10,382 | 50 | $424,169 | Oct 30 | United International Pictures | false |
| 143 | Three Monkeys | - | - | - | $10,241 | 3 | $10,241 | May 7 | Cine Colombia | false |
| 144 | Grace Is Gone | - | - | - | $9,605 | 7 | $9,605 | Apr 30 | Cine Colombia | false |
| 145 | Trade 2010 Re-release | - | - | - | $9,187 | 12 | $9,187 | Nov 26 | Cine Colombia | false |
| 146 | Shadows | - | - | - | $9,054 | 8 | $25,636 | Jan 22 | Cine Colombia | false |
| 147 | Synecdoche, New York | - | - | - | $8,385 | 3 | $8,385 | Nov 26 | Cineplex | false |
| 148 | Whiteout | - | - | - | $4,991 | 31 | $217,156 | Dec 4 | Warner Bros. | false |
| 149 | Looking for Eric | - | - | - | $3,831 | 1 | $5,223 | May 14 | - | false |
| 150 | Giant | - | - | - | $3,420 | 3 | $3,420 | Mar 19 | Cine Colombia | false |
| 151 | Cloud 9 2009 Re-release | - | - | - | $2,347 | 2 | $52,628 | Jul 30 | Cine Colombia | false |
| 152 | Planet 51 | - | - | - | $2,064 | 115 | $967,122 | Nov 20 | Cine Colombia | false |
| 153 | Taking Woodstock | - | - | - | $1,903 | 3 | $1,903 | Mar 5 | United International Pictures | false |
| 154 | The Girl in the Park 2010 Re-release | - | - | - | $1,447 | 3 | $16,461 | Dec 10 | Cine Colombia | false |
| 155 | A Christmas Carol | - | - | - | $690 | 134 | $1,768,192 | Nov 13 | Walt Disney Pictures | false |
