| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Up | - | - | - | $3,585,744 | 64 | $3,599,407 | Jul 23 | Walt Disney Pictures | false |
| 2 | Ice Age: Dawn of the Dinosaurs | - | - | - | $3,517,576 | 59 | $3,517,576 | Jul 1 | 20th Century Fox International | false |
| 3 | 2012 | - | - | - | $2,522,822 | 29 | $2,675,652 | Nov 12 | Sony Pictures Releasing | false |
| 4 | Avatar | - | - | - | $2,295,903 | 35 | $13,488,099 | Dec 17 | 20th Century Fox International | false |
| 5 | Inglourious Basterds | - | - | - | $2,255,778 | 29 | $2,255,778 | Sep 17 | United International Pictures | false |
| 6 | Harry Potter and the Half-Blood Prince | - | - | - | $2,147,750 | 49 | $2,147,750 | Jul 16 | Warner Bros. | false |
| 7 | The Hangover | - | - | - | $1,737,386 | 29 | $1,737,386 | Jul 30 | Warner Bros. | false |
| 8 | Fast & Furious | - | - | - | $1,563,998 | 29 | $1,563,998 | Apr 2 | United International Pictures | false |
| 9 | Monsters vs. Aliens | - | - | - | $1,497,532 | 55 | $1,497,532 | Mar 26 | United International Pictures | false |
| 10 | Cloudy with a Chance of Meatballs | - | - | - | $1,310,300 | 21 | $1,528,705 | Oct 1 | Sony Pictures Releasing | false |
| 11 | The Proposal | - | - | - | $1,236,949 | 25 | $1,241,817 | Jun 18 | Walt Disney Pictures | false |
| 12 | Angels & Demons | - | - | - | $1,148,249 | 34 | $1,148,249 | May 14 | Sony Pictures Releasing | false |
| 13 | G-Force | - | - | - | $1,070,181 | 36 | $1,070,181 | Aug 13 | Walt Disney Pictures | false |
| 14 | Brüno | - | - | - | $892,830 | 30 | $892,830 | Jul 9 | Forum Hungary | false |
| 15 | Transformers: Revenge of the Fallen | - | - | - | $832,107 | 28 | $872,383 | Jun 24 | United International Pictures | false |
| 16 | My Sister's Keeper | - | - | - | $814,556 | 16 | $816,316 | Oct 1 | Warner Bros. | false |
| 17 | The Taking of Pelham 123 | - | - | - | $710,534 | 19 | $710,534 | Jul 23 | Sony Pictures Releasing | false |
| 18 | Gran Torino | - | - | - | $706,146 | 19 | $749,105 | Feb 26 | Warner Bros. | false |
| 19 | The Final Destination | - | - | - | $691,132 | 16 | $691,132 | Sep 10 | Warner Bros. | false |
| 20 | 17 Again | - | - | - | $686,569 | 25 | $727,674 | Apr 16 | Forum Hungary | false |
| 21 | The Ugly Truth | - | - | - | $673,793 | 20 | $673,793 | Aug 13 | Sony Pictures Releasing | false |
| 22 | Ghosts of Girlfriends Past | - | - | - | $649,335 | 24 | $649,335 | Jul 2 | Warner Bros. | false |
| 23 | Beverly Hills Chihuahua | - | - | - | $614,906 | 29 | $616,065 | Mar 5 | Walt Disney Pictures | false |
| 24 | Surrogates | - | - | - | $587,897 | 25 | $590,193 | Sep 24 | Walt Disney Pictures | false |
| 25 | Duplicity | - | - | - | $585,401 | 29 | $585,401 | Mar 19 | United International Pictures | false |
| 26 | Terminator Salvation | - | - | - | $564,572 | 29 | $564,572 | Jun 4 | Sony Pictures Releasing | false |
| 27 | Julie & Julia | - | - | - | $543,132 | 13 | $543,132 | Oct 8 | Sony Pictures Releasing | false |
| 28 | Couples Retreat | - | - | - | $528,567 | 29 | $785,683 | Dec 10 | United International Pictures | false |
| 29 | Marley & Me | - | - | - | $512,126 | 19 | $514,417 | Mar 12 | 20th Century Fox International | false |
| 30 | X-Men Origins: Wolverine | - | - | - | $469,490 | 18 | $469,490 | Apr 30 | 20th Century Fox International | false |
| 31 | The Time Traveler's Wife | - | - | - | $442,287 | 15 | $448,482 | Aug 20 | Forum Hungary | false |
| 32 | A Christmas Carol | - | - | - | $435,489 | 18 | $447,277 | Nov 26 | Walt Disney Pictures | false |
| 33 | The Tale of Despereaux | - | - | - | $426,079 | 25 | $426,079 | Jul 30 | United International Pictures | false |
| 34 | State of Play | - | - | - | $411,511 | 20 | $489,449 | Jun 4 | United International Pictures | false |
| 35 | Public Enemies | - | - | - | $393,145 | 26 | $393,145 | Jul 9 | United International Pictures | false |
| 36 | Night at the Museum: Battle of the Smithsonian | - | - | - | $365,475 | 19 | $365,475 | May 21 | 20th Century Fox International | false |
| 37 | Coraline | - | - | - | $341,195 | 30 | $341,195 | Jun 25 | United International Pictures | false |
| 38 | Hotel for Dogs | - | - | - | $328,382 | 15 | $328,382 | Mar 12 | United International Pictures | false |
| 39 | The Reader | - | - | - | $297,966 | 17 | $526,510 | Feb 12 | - | false |
| 40 | He's Just Not That Into You | - | - | - | $293,583 | 24 | $712,523 | Feb 6 | Forum Hungary | false |
| 41 | Star Trek | - | - | - | $292,023 | 22 | $292,023 | May 7 | United International Pictures | false |
| 42 | Watchmen | - | - | - | $277,922 | 25 | $277,922 | Mar 5 | United International Pictures | false |
| 43 | G.I. Joe: The Rise of Cobra | - | - | - | $255,777 | 25 | $255,777 | Aug 20 | United International Pictures | false |
| 44 | Race to Witch Mountain | - | - | - | $237,486 | 24 | $277,815 | Apr 2 | Walt Disney Pictures | false |
| 45 | 500 Days of Summer | - | - | - | $208,131 | 9 | $208,131 | Nov 12 | 20th Century Fox International | false |
| 46 | Where the Wild Things Are | - | - | - | $172,159 | 12 | $183,891 | Dec 10 | Warner Bros. | false |
| 47 | Confessions of a Shopaholic | - | - | - | $171,943 | 24 | $260,853 | Feb 19 | - | false |
| 48 | Zombieland | - | - | - | $169,894 | 15 | $169,894 | Dec 3 | Sony Pictures Releasing | false |
| 49 | Coco Before Chanel | - | - | - | $159,621 | 11 | $161,013 | Jun 11 | Forum Hungary | false |
| 50 | Toy Story 2009 Re-release | - | - | - | $159,522 | 15 | $159,522 | Oct 1 | Walt Disney Pictures | false |
| 51 | Hannah Montana: The Movie | - | - | - | $157,292 | 20 | $175,395 | Apr 9 | Walt Disney Pictures | false |
| 52 | This Is It | - | - | - | $154,114 | 15 | $154,114 | Oct 29 | Sony Pictures Releasing | false |
| 53 | Everybody's Fine | - | - | - | $134,771 | 13 | $379,816 | Dec 24 | Walt Disney Pictures | false |
| 54 | The Unborn | - | - | - | $96,138 | 18 | $96,138 | Feb 26 | - | false |
| 55 | Inkheart | - | - | - | $94,950 | 20 | $94,950 | Feb 26 | - | false |
| 56 | The Pink Panther 2 | - | - | - | $84,288 | 10 | $84,288 | Mar 5 | - | false |
| 57 | Friday the 13th | - | - | - | $80,709 | 16 | $80,709 | Mar 12 | - | false |
| 58 | Bride Wars | - | - | - | $80,625 | 15 | $222,026 | Feb 12 | - | false |
| 59 | Toy Story 2 2009 Re-release | - | - | - | $79,072 | 14 | $79,072 | Oct 29 | Walt Disney Pictures | false |
| 60 | Crossing Over | - | - | - | $60,191 | 10 | $60,191 | Mar 12 | - | false |
| 61 | Seven Pounds | - | - | - | $46,078 | 10 | $214,788 | Feb 5 | - | false |
| 62 | Valkyrie | - | - | - | $40,601 | 11 | $386,223 | Jan 29 | - | false |
| 63 | Revolutionary Road | - | - | - | $38,055 | 14 | $359,830 | Jan 29 | - | false |
| 64 | The Curious Case of Benjamin Button | - | - | - | $34,283 | 25 | $933,099 | Jan 15 | - | false |
| 65 | Bolt | - | - | - | $28,249 | 29 | $1,615,026 | Dec 4 | - | false |
| 66 | Underworld: Rise of the Lycans | - | - | - | $20,322 | 5 | $20,322 | Mar 19 | - | false |
| 67 | Yes Man | - | - | - | $16,739 | 18 | $1,390,320 | Dec 25 | - | false |
| 68 | Rachel Getting Married | - | - | - | $14,593 | 1 | $14,593 | Mar 1 | - | false |
| 69 | Bedtime Stories | - | - | - | $10,718 | 21 | $637,106 | Dec 25 | - | false |
| 70 | The International | - | - | - | $6,028 | 1 | $10,144 | Apr 2 | Sony Pictures Releasing | false |
| 71 | Frost/Nixon | - | - | - | $5,355 | 7 | $45,480 | Feb 5 | - | false |
| 72 | Jonas Brothers: The 3D Concert Experience | - | - | - | $4,540 | 7 | $4,540 | Mar 5 | - | false |
