| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Babel | - | - | - | $6,312,725 | 300 | $7,349,426 | Nov 10 | United International Pictures | false |
| 2 | Eragon | - | - | - | $4,756,011 | 700 | $10,643,431 | Dec 15 | 20th Century Fox International | false |
| 3 | Barnyard | - | - | - | $4,532,992 | 385 | $4,688,873 | Oct 27 | United International Pictures | false |
| 4 | Happy Feet | - | - | - | $4,374,229 | 606 | $6,252,783 | Dec 8 | Warner Bros. | false |
| 5 | Casino Royale | - | - | - | $4,178,684 | 564 | $6,557,256 | Dec 8 | Sony Pictures Releasing | false |
| 6 | Deja Vu | - | - | - | $4,034,754 | 400 | $4,168,156 | Nov 24 | Buena Vista International | false |
| 7 | Pan's Labyrinth | - | - | - | $3,708,915 | 190 | $6,883,588 | Oct 20 | Warner Bros. | false |
| 8 | The Illusionist | - | - | - | $3,130,841 | 250 | $7,272,964 | Sep 29 | Videocine | false |
| 9 | Open Season | - | - | - | $3,108,698 | 591 | $7,835,953 | Oct 7 | Sony Pictures Releasing | false |
| 10 | The Departed | - | - | - | $2,982,026 | 350 | $3,480,385 | Nov 17 | Warner Bros. | false |
| 11 | The Prestige | - | - | - | $2,793,008 | 250 | $2,985,101 | Nov 2 | Warner Bros. | false |
| 12 | Flushed Away | - | - | - | $2,763,857 | 600 | $6,616,758 | Dec 15 | United International Pictures | false |
| 13 | The Grudge 2 | - | - | - | $2,351,074 | 216 | $2,618,414 | Nov 2 | Gussi Films | false |
| 14 | The Santa Clause 3: The Escape Clause | - | - | - | $2,348,516 | 310 | $2,455,059 | Dec 1 | Buena Vista International | false |
| 15 | The Covenant | - | - | - | $2,263,023 | 300 | $2,263,023 | Oct 27 | Sony Pictures Releasing | false |
| 16 | Children of Men | - | - | - | $2,035,909 | 258 | $2,505,554 | Nov 24 | United International Pictures | false |
| 17 | On the Edge | - | - | - | $1,943,086 | 300 | $2,119,800 | Nov 24 | Videocine | false |
| 18 | The Guardian | - | - | - | $1,842,167 | 400 | $3,353,795 | Oct 20 | Buena Vista International | false |
| 19 | Saw III | - | - | - | $1,241,739 | 300 | $1,297,261 | Nov 17 | Buena Vista International | false |
| 20 | Deck the Halls | - | - | - | $993,910 | 250 | $1,169,660 | Dec 8 | 20th Century Fox International | false |
| 21 | Volver | - | - | - | $985,236 | 200 | $1,050,278 | Oct 27 | 20th Century Fox International | false |
| 22 | A Good Year | - | - | - | $691,751 | 200 | $1,034,183 | Dec 1 | 20th Century Fox International | false |
| 23 | Open Water 2: Adrift | - | - | - | $569,811 | 130 | $1,537,277 | Oct 6 | Videocine | false |
| 24 | Material Girls | - | - | - | $508,533 | 176 | $1,628,878 | Dec 15 | Videocine | false |
| 25 | Gridiron Gang | - | - | - | $485,688 | 180 | $878,199 | Dec 1 | Sony Pictures Releasing | false |
| 26 | Lucky Number Slevin | - | - | - | $478,889 | 76 | $1,127,224 | Oct 27 | Gussi Films | false |
| 27 | The Night Listener | - | - | - | $475,298 | 267 | $577,521 | Dec 1 | Azteca Films | false |
| 28 | Tired of Kissing Frogs | - | - | - | $432,855 | 350 | $6,633,548 | Dec 20 | Buena Vista International | false |
| 29 | Pulse | - | - | - | $393,985 | 75 | $1,229,012 | Oct 20 | Gussi Films | false |
| 30 | The Devil Wears Prada | - | - | - | $391,170 | 166 | $5,691,175 | Sep 22 | 20th Century Fox International | false |
| 31 | The Wicker Man | - | - | - | $388,183 | 74 | $1,342,206 | Nov 10 | Gussi Films | false |
| 32 | The Nightmare Before Christmas 2006 3D Release | - | - | - | $373,416 | 5 | $415,951 | Nov 17 | Buena Vista International | false |
| 33 | Ugly Me | - | - | - | $311,381 | 165 | $2,136,673 | Oct 6 | United International Pictures | false |
| 34 | The Science of Sleep | - | - | - | $245,537 | 125 | $407,465 | Nov 17 | Tarantula Films | false |
| 35 | The Nativity Story | - | - | - | $235,074 | 220 | $332,714 | Dec 1 | Gussi Films | false |
| 36 | World Trade Center | - | - | - | $214,235 | 91 | $5,165,796 | Sep 15 | United International Pictures | false |
| 37 | Keeping Mum | - | - | - | $206,738 | 32 | $758,745 | Sep 8 | Gussi Films | false |
| 38 | Elsa & Fred | - | - | - | $181,026 | 50 | $804,202 | Aug 4 | Zima Entertainment | false |
| 39 | A Sound of Thunder | - | - | - | $156,294 | 45 | $953,667 | Oct 6 | Gussi Films | false |
| 40 | Little Man | - | - | - | $155,605 | 130 | $5,340,605 | Sep 14 | Sony Pictures Releasing | false |
| 41 | United 93 | - | - | - | $140,689 | 71 | $2,425,037 | Aug 18 | United International Pictures | false |
| 42 | Opal Dream | - | - | - | $103,218 | 102 | $121,925 | Nov 2 | Azteca Films | false |
| 43 | The Mistress of Spices | - | - | - | $102,811 | 100 | $220,385 | Nov 17 | Azteca Films | false |
| 44 | Karol - The Pope, the Man | - | - | - | $82,865 | 38 | $1,044,519 | Sep 22 | - | false |
| 45 | Guadalupe: El Milagro Y El Mensaje | - | - | - | $81,534 | 94 | $650,811 | Dec 1 | - | false |
| 46 | Night at the Museum | - | - | - | $77,549 | 708 | $20,409,103 | Dec 25 | 20th Century Fox International | false |
| 47 | Little Miss Sunshine | - | - | - | $69,351 | 37 | $427,643 | Nov 24 | 20th Century Fox International | false |
| 48 | Jackass Number Two | - | - | - | $64,521 | 100 | $226,398 | Dec 1 | United International Pictures | false |
| 49 | Invincible | - | - | - | $63,184 | 50 | $377,784 | Nov 10 | Gussi Films | false |
| 50 | Creep | - | - | - | $57,558 | 40 | $57,558 | Oct 27 | Decine | false |
| 51 | Step Up | - | - | - | $51,442 | 47 | $396,074 | Oct 13 | Videocine | false |
| 52 | All the King's Men | - | - | - | $7,210 | 14 | $251,014 | Nov 2 | Sony Pictures Releasing | false |
