| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum | $282,232 | -18.1% | 41 | -32 | $6,883 | $1,133,115 | 3 | 20th Century Fox International | false | false |
| 2 | 2 | Babel | $124,020 | -22.3% | 33 | - | $3,758 | $468,333 | 3 | United International Pictures | false | false |
| 3 | - | Blood Diamond | $106,117 | - | 23 | - | $4,613 | $106,117 | 1 | Warner Bros. | true | false |
| 4 | 3 | The Illusionist | $51,019 | -14.7% | 20 | -2 | $2,550 | $310,619 | 4 | Transeuropa | false | false |
| 5 | 5 | Eragon | $50,833 | -7.3% | 24 | -14 | $2,118 | $785,961 | 5 | 20th Century Fox International | false | false |
| 6 | 4 | Children of Men | $42,792 | -26.4% | 25 | -1 | $1,711 | $100,927 | 2 | United International Pictures | false | false |
| 7 | 7 | Flushed Away | $34,374 | -9.2% | 25 | -3 | $1,374 | $982,047 | 8 | United International Pictures | false | false |
| 8 | 6 | Deja Vu | $32,942 | -27.1% | 20 | -3 | $1,647 | $221,328 | 4 | Buena Vista International | false | false |
| 9 | 8 | Flags of Our Fathers | $28,113 | -14.5% | 10 | - | $2,811 | $60,983 | 2 | Warner Bros. | false | false |
| 10 | 15 | Little Miss Sunshine | $26,538 | +193.6% | 4 | - | $6,634 | $115,785 | 7 | 20th Century Fox International | false | false |
| 11 | 10 | The Departed | $23,814 | +22.1% | 9 | -2 | $2,646 | $753,595 | 12 | Warner Bros. | false | false |
| 12 | - | Cry Wolf | $21,323 | - | 10 | - | $2,132 | $21,323 | 1 | Bazuca Films | true | false |
| 13 | 9 | Charlotte's Web | $16,303 | -32.2% | 13 | -7 | $1,254 | $126,720 | 4 | United International Pictures | false | false |
| 14 | 11 | Marie Antoinette | $13,983 | -23% | 4 | - | $3,495 | $95,622 | 4 | Sony Pictures Releasing | false | false |
| 15 | 14 | Happy Feet | $10,892 | +6.9% | 7 | -2 | $1,556 | $801,936 | 10 | Warner Bros. | false | false |
| 16 | - | Heading South | $9,779 | - | 8 | - | $1,222 | $9,779 | 1 | Andes Films | true | false |
| 17 | 13 | Casino Royale | $6,130 | -51.3% | 2 | -5 | $3,065 | $777,769 | 9 | Sony Pictures Releasing | false | false |
| 18 | 12 | Saw III | $5,849 | -58.7% | 4 | -6 | $1,462 | $262,846 | 8 | Buena Vista International | false | false |
| 19 | - | The Covenant | $2,947 | - | 5 | - | $589 | $137,097 | 6 | Sony Pictures Releasing | false | false |
