| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Perfume: The Story of a Murderer | $1,559,476 | - | 200 | - | $7,797 | $1,559,476 | 1 | Gussi Films | true | false |
| 2 | 2 | Night at the Museum | $1,522,106 | -4.3% | 680 | -27 | $2,238 | $17,282,665 | 5 | 20th Century Fox International | false | false |
| 3 | 1 | Rocky Balboa | $1,268,974 | -21.2% | 278 | +248 | $4,564 | $3,704,163 | 2 | 20th Century Fox International | false | false |
| 4 | 3 | The Holiday | $830,873 | +18.7% | 250 | - | $3,323 | $2,087,534 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Fuera del cielo | $735,297 | +9.7% | 150 | - | $4,901 | $1,858,806 | 2 | Videocine | false | false |
| 6 | 5 | Tired of Kissing Frogs | $718,353 | +30.2% | 288 | -22 | $2,494 | $5,999,803 | 6 | Buena Vista International | false | false |
| 7 | 6 | Eragon | $375,978 | -4.9% | 250 | -330 | $1,503 | $10,370,634 | 6 | 20th Century Fox International | false | false |
| 8 | 7 | Flushed Away | $258,315 | -3.6% | 201 | -89 | $1,285 | $6,262,389 | 6 | United International Pictures | false | false |
| 9 | 14 | Unaccompanied Minors | $225,182 | +109.1% | 138 | +34 | $1,631 | $1,068,309 | 5 | Warner Bros. | false | false |
| 10 | 8 | Charlotte's Web | $210,593 | -4.5% | 200 | -69 | $1,052 | $1,960,491 | 4 | United International Pictures | false | false |
| 11 | - | The Long Weekend | $190,527 | - | 100 | - | $1,905 | $190,527 | 1 | Videocine | true | false |
| 12 | 10 | Material Girls | $187,907 | +36.5% | 116 | -2 | $1,619 | $1,466,931 | 6 | Videocine | false | false |
| 13 | 11 | The Wicker Man | $178,198 | +46.4% | 70 | -1 | $2,545 | $962,559 | 11 | Gussi Films | false | false |
| 14 | 13 | Stormbreaker | $158,104 | +36.1% | 122 | -24 | $1,295 | $706,612 | 3 | Azteca Films | false | false |
| 15 | 16 | Lucky Number Slevin | $151,022 | +62.1% | 64 | -5 | $2,359 | $966,733 | 13 | Gussi Films | false | false |
| 16 | 17 | Pulse | $146,324 | +62.3% | 60 | +3 | $2,438 | $1,056,341 | 14 | Gussi Films | false | false |
| 17 | 12 | Borat | $106,130 | -11.7% | 51 | -9 | $2,080 | $610,440 | 3 | 20th Century Fox International | false | false |
| 18 | 9 | Casino Royale | $100,724 | -33.5% | 92 | -77 | $1,094 | $6,557,256 | 7 | Sony Pictures Releasing | false | false |
| 19 | - | Scoop | $96,832 | - | 21 | - | $4,611 | $96,832 | 1 | Gussi Films | true | false |
| 20 | - | The Science of Sleep | $81,170 | - | 68 | - | $1,193 | $333,826 | 10 | Tarantula Films | false | false |
