| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Casino Royale | $823,852 | -35.6% | 99 | +1 | $8,321 | $4,459,778 | 4 | Sony Pictures Releasing | false | false |
| 2 | - | The Departed | $671,393 | - | 63 | - | $10,657 | $727,708 | 2 | Warner Bros. | false | false |
| 3 | 2 | Happy Feet | $356,169 | -0.2% | 82 | +1 | $4,343 | $723,499 | 3 | Warner Bros. | false | false |
| 4 | - | Flushed Away | $310,714 | - | 71 | - | $4,376 | $329,470 | 2 | United International Pictures | false | false |
| 5 | 5 | Open Season | $72,557 | -15.8% | 96 | -4 | $755 | $1,187,491 | 6 | Sony Pictures Releasing | false | false |
| 6 | 11 | The Santa Clause 3: The Escape Clause | $71,197 | +60% | 67 | +3 | $1,062 | $439,405 | 7 | Buena Vista International | false | false |
| 7 | 4 | Jackass Number Two | $65,994 | -25.5% | 22 | - | $2,999 | $153,696 | 3 | United International Pictures | false | false |
| 8 | 3 | Borat | $64,590 | -37.2% | 54 | +2 | $1,196 | $1,578,266 | 7 | - | false | false |
| 9 | 6 | 7 Dwarves: The Forest Is Not Enough | $59,553 | -8.9% | 63 | -6 | $945 | $3,939,324 | 8 | United International Pictures | false | false |
| 10 | 7 | Grave Decisions | $53,756 | -12.2% | 28 | - | $1,919 | $312,556 | 5 | Luna Filmverleih | false | false |
| 11 | 8 | The Devil Wears Prada | $35,322 | -29.4% | 44 | -19 | $802 | $3,547,358 | 10 | - | false | false |
| 12 | 10 | Little Miss Sunshine | $33,048 | -31.4% | 14 | -1 | $2,360 | $80,713 | 3 | - | false | false |
| 13 | 9 | A Good Year | $31,532 | -36% | 41 | -5 | $769 | $527,521 | 6 | 20th Century Fox International | false | false |
| 14 | 16 | Pettson & Findus: The Santa Machine | $31,138 | +36% | 30 | - | $1,037 | $81,951 | 4 | Filmladen | false | false |
| 15 | 13 | Scoop | $30,603 | -26.3% | 9 | - | $3,400 | $218,442 | 5 | Constantin Film | false | false |
| 16 | - | The Nativity Story | $28,103 | - | 35 | - | $802 | $29,725 | 2 | Warner Bros. | false | false |
| 17 | - | A Friend of Mine | $18,097 | - | 10 | - | $1,809 | $18,097 | 2 | Filmladen | false | false |
| 18 | 17 | Slumming | $11,432 | -40.8% | 11 | - | $1,039 | $56,687 | 4 | Filmladen | false | false |
| 19 | 18 | Goya's Ghosts | $10,668 | -42.8% | 8 | - | $1,333 | $56,596 | 4 | Constantin Film | false | false |
| 20 | 20 | Marie Antoinette | $10,476 | -26% | 16 | -2 | $654 | $265,080 | 7 | Sony Pictures Releasing | false | false |
