| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Teenage Mutant Ninja Turtles II: The Secret of the Ooze | $19,522,844 | -27% | 2,868 | - | $6,807 | $46,251,752 | 2 | New Line Cinema | false | false |
| 2 | 2 | The Silence of the Lambs | $8,326,256 | -14.8% | 1,616 | +8 | $5,152 | $89,664,613 | 8 | Orion Pictures | false | false |
| 3 | 3 | Dances with Wolves | $7,844,491 | +19.8% | 1,621 | +83 | $4,839 | $146,951,427 | 21 | Orion Pictures | false | false |
| 4 | - | Career Opportunities | $5,556,675 | - | 1,440 | - | $3,858 | $5,556,675 | 1 | Universal Pictures | true | false |
| 5 | 4 | New Jack City | $5,461,360 | -13.8% | 905 | - | $6,034 | $29,608,714 | 4 | Warner Bros. | false | false |
| 6 | 6 | Sleeping with the Enemy | $4,734,538 | -16.8% | 1,478 | -39 | $3,203 | $80,357,168 | 8 | Twentieth Century Fox | false | false |
| 7 | 5 | Class Action | $4,229,578 | -25.8% | 1,132 | +24 | $3,736 | $15,475,638 | 3 | Twentieth Century Fox | false | false |
| 8 | 8 | Home Alone | $3,778,835 | -6.9% | 1,762 | +5 | $2,144 | $258,123,449 | 20 | Twentieth Century Fox | false | false |
| 9 | 7 | The Hard Way | $2,878,075 | -30.4% | 1,510 | -119 | $1,906 | $20,424,205 | 4 | Universal Pictures | false | false |
| 10 | - | The Five Heartbeats | $2,395,376 | - | 862 | - | $2,778 | $2,395,376 | 1 | Twentieth Century Fox | true | false |
| 11 | 9 | The Doors | $2,214,900 | -33.8% | 1,035 | -151 | $2,140 | $30,148,246 | 5 | TriStar Pictures | false | false |
| 12 | 10 | The Perfect Weapon | $2,028,219 | -36.5% | 1,082 | -147 | $1,874 | $10,324,439 | 3 | Paramount Pictures | false | false |
| 13 | 11 | Guilty by Suspicion | $1,642,946 | -34.3% | 585 | -232 | $2,808 | $7,286,346 | 3 | Warner Bros. | false | false |
| 14 | 14 | Kindergarten Cop | $1,187,825 | +21.8% | 552 | +4 | $2,151 | $85,448,848 | 15 | Universal Pictures | false | false |
| 15 | 13 | The Long Walk Home | $900,432 | -36.2% | 272 | +2 | $3,310 | $2,579,821 | 15 | Miramax | false | false |
| 16 | - | Awakenings | $869,644 | - | 506 | +10 | $1,718 | $48,962,883 | 15 | Columbia Pictures | false | false |
| 17 | - | The Unborn | $224,941 | - | 55 | - | $4,089 | $224,941 | 1 | Concorde Pictures | true | false |
| 18 | 16 | Defending Your Life | $149,417 | +8.5% | 3 | - | $49,805 | $287,168 | 2 | Warner Bros. | false | false |
