| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Me contro Te - il Film: Missione Giungla | $1,129,033 | -54.9% | 541 | +21 | $2,086 | $4,166,216 | 2 | Warner Bros. | false | false |
| 2 | - | The First Day of My Life | $961,630 | - | 500 | - | $1,923 | $961,630 | 1 | Medusa Distribuzione | true | false |
| 3 | 2 | Avatar: The Way of Water | $922,414 | -34.7% | 281 | -65 | $3,282 | $47,016,317 | 7 | Walt Disney Studios Motion Pictures | false | false |
| 4 | - | Plane | $720,031 | - | 309 | - | $2,330 | $782,185 | 1 | - | true | false |
| 5 | 3 | Thank You Guys | $400,777 | -41.4% | 428 | -74 | $936 | $2,249,669 | 3 | - | false | false |
| 6 | 4 | Tre di troppo | $216,321 | -47.8% | 212 | -104 | $1,020 | $5,011,421 | 5 | Sony Pictures Releasing | false | false |
| 7 | 5 | The Eight Mountains | $207,045 | -49.3% | 214 | -92 | $967 | $5,866,036 | 6 | - | false | false |
| 8 | 7 | Puss in Boots: The Last Wish | $197,413 | -17.1% | 172 | -20 | $1,147 | $6,183,598 | 8 | Universal Pictures International (UPI) | false | false |
| 9 | - | Anna Frank E Il Diario Segreto | $172,914 | - | 201 | - | $860 | $499,203 | 18 | Lucky Red | false | false |
| 10 | 6 | M3GAN | $124,643 | -57% | 140 | -79 | $890 | $2,429,945 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | 8 | The Fabelmans | $123,751 | -37.5% | 121 | -93 | $1,022 | $3,169,408 | 6 | 01 Distribution | false | false |
| 12 | - | Billie Eilish Live at the O2 | $108,945 | - | 132 | - | $825 | $108,945 | 1 | N/A | true | false |
| 13 | 9 | Il grande giorno | $59,643 | -59.5% | 79 | -57 | $754 | $7,787,789 | 6 | Medusa Distribuzione | false | false |
| 14 | 10 | I migliori giorni | $45,227 | -58.9% | 60 | -75 | $753 | $2,000,849 | 5 | - | false | false |
| 15 | 13 | Io vivo altrove! | $33,699 | -29.7% | 28 | +2 | $1,203 | $103,788 | 2 | Adler Entertainment | false | false |
| 16 | - | La seconda via | $33,450 | - | 54 | - | $619 | $33,450 | 1 | RS Productions. | true | false |
| 17 | - | Pathaan | $32,436 | - | 21 | - | $1,544 | $32,598 | 1 | - | true | false |
| 18 | 12 | She Said | $6,099 | -92.1% | 27 | -167 | $225 | $102,262 | 2 | Universal Pictures International (UPI) | false | false |
| 19 | 33 | Mrs. Harris Goes to Paris | $2,313 | -54.5% | 5 | - | $462 | $498,289 | 11 | Universal Pictures International (UPI) | false | false |
| 20 | - | House of Gucci | $1,022 | - | 1 | - | $1,022 | $6,067,740 | 59 | Paramount Pictures | false | false |
| 21 | 47 | Strange World | $735 | -62.1% | - | - | - | $1,639,234 | 10 | Walt Disney Studios Motion Pictures | false | false |
