| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Uncharted | $1,495,634 | - | 506 | - | $2,955 | $4,759,771 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | Death on the Nile | $701,207 | -47.7% | 443 | -203 | $1,582 | $5,025,374 | 3 | Walt Disney Pictures | false | false |
| 3 | - | Belfast | $505,349 | - | 377 | - | $1,340 | $505,349 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 3 | Ennio | $488,064 | -33.9% | 525 | +64 | $929 | $1,849,480 | 2 | Lucky Red | false | false |
| 5 | - | The Shadow of the Day | $158,425 | - | 257 | - | $616 | $158,425 | 1 | 01 Distribution | true | false |
| 6 | - | Dark Glasses | $124,603 | - | 271 | - | $459 | $124,603 | 1 | - | true | false |
| 7 | 4 | Marry Me | $112,204 | -61.4% | 180 | -157 | $623 | $1,120,262 | 3 | Universal Pictures | false | false |
| 8 | 5 | Spider-Man: No Way Home | $98,590 | -40.2% | 116 | -44 | $849 | $27,639,946 | 11 | Sony Pictures Releasing | false | false |
| 9 | 6 | The Wolf and the Lion | $89,132 | -45.4% | 210 | -58 | $424 | $2,477,520 | 6 | 01 Distribution | false | false |
| 10 | 12 | Sing 2 | $43,951 | -3% | 89 | +25 | $493 | $2,660,735 | 10 | Universal Pictures International (UPI) | false | false |
| 11 | 7 | Nightmare Alley | $37,393 | -72.1% | 70 | -119 | $534 | $2,012,088 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 12 | - | Beautiful Minds | $33,446 | - | 154 | - | $217 | $33,446 | 1 | BIM Distribuzione | true | false |
| 13 | 8 | Me contro Te: Il film - Persi nel tempo | $32,106 | -51.3% | 116 | -38 | $276 | $3,912,223 | 9 | Warner Bros. | false | false |
| 14 | - | Seance | $30,378 | - | 134 | - | $226 | $30,378 | 1 | Adler Entertainment | true | false |
| 15 | 9 | After Love | $27,348 | -56.5% | 41 | -19 | $667 | $216,420 | 3 | Teodora Film | false | false |
| 16 | 10 | Leonora addio | $25,312 | -54.6% | 51 | -43 | $496 | $96,785 | 2 | 01 Distribution | false | false |
| 17 | - | The Legionnaire | $15,545 | - | 22 | - | $706 | $15,545 | 1 | Fandango | true | false |
| 18 | - | Senza fine | $14,914 | - | 42 | - | $355 | $36,176 | 1 | I Wonder Pictures | true | false |
| 19 | 13 | Small Body | $12,459 | -56.3% | 18 | -14 | $692 | $123,355 | 3 | Nefertiti Film | false | false |
| 20 | 16 | Encanto | $9,822 | -39.3% | - | - | - | $5,335,067 | 14 | Walt Disney Studios Motion Pictures | false | false |
| 21 | 22 | West Side Story | $2,965 | +86% | - | - | - | $610,490 | 10 | Walt Disney Studios Motion Pictures | false | false |
| 22 | 21 | Parallel Mothers | $2,833 | +25.8% | 4 | +1 | $708 | $2,758,428 | 18 | Warner Bros. | false | false |
| 23 | 25 | The French Dispatch | $717 | +78.8% | - | - | - | $2,441,059 | 16 | Walt Disney Studios Motion Pictures | false | false |
