| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man: No Way Home | $4,397,109 | -27.7% | 679 | -1 | $6,475 | $115,054,387 | 5 | Sony Pictures Releasing | false | false |
| 2 | - | Scream | $3,375,971 | - | 622 | - | $5,427 | $3,375,971 | 1 | Paramount Pictures | true | false |
| 3 | 2 | The King's Man | $858,103 | -30.2% | 577 | -59 | $1,487 | $8,834,084 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 4 | 4 | Clifford the Big Red Dog | $718,144 | -15.2% | 620 | -11 | $1,158 | $10,910,719 | 6 | Paramount Pictures International | false | false |
| 5 | 3 | Licorice Pizza | $538,824 | -54.9% | 369 | +167 | $1,460 | $2,089,438 | 2 | - | false | false |
| 6 | 6 | West Side Story | $478,686 | -13.1% | 490 | -72 | $976 | $9,027,902 | 6 | Walt Disney Pictures | false | false |
| 7 | 5 | The Matrix Resurrections | $409,166 | -41.4% | 477 | -123 | $857 | $9,567,522 | 4 | Warner Bros. | false | false |
| 8 | 9 | Encanto | $303,111 | +4.5% | 476 | +1 | $636 | $9,355,617 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 9 | 8 | House of Gucci | $237,537 | -18.6% | 227 | -62 | $1,046 | $12,900,417 | 8 | Universal Pictures | false | false |
| 10 | 7 | The 355 | $220,847 | -55.7% | 430 | -60 | $513 | $976,156 | 2 | Universal Pictures International (UPI) | false | false |
| 11 | 10 | Ghostbusters: Afterlife | $123,907 | -22.3% | 235 | -19 | $527 | $15,611,205 | 9 | Sony Pictures Releasing | false | false |
| 12 | 11 | Boiling Point | $100,595 | -6.4% | 74 | +21 | $1,359 | $271,271 | 2 | Vertigo Films | false | false |
| 13 | - | The Boss Baby: Family Business | $62,902 | - | 353 | - | $178 | $9,954,768 | 13 | Universal Pictures International (UPI) | false | false |
| 14 | - | Memoria | $54,862 | - | 56 | - | $979 | $54,862 | 1 | - | true | false |
| 15 | 12 | The Electrical Life of Louis Wain | $43,568 | -52.1% | 164 | -100 | $265 | $485,372 | 3 | StudioCanal UK | false | false |
| 16 | - | Cow | $28,790 | - | 34 | - | $846 | $28,790 | 1 | MUBI | true | false |
| 17 | 13 | '83 | $24,263 | -47.9% | 28 | -24 | $866 | $761,774 | 4 | Reliance Big Pictures | false | false |
| 18 | - | Bangarraju | $22,318 | - | 27 | - | $826 | $22,318 | 1 | Sun Media | true | false |
| 19 | 20 | Antarctica 3D: On the Edge | $13,193 | +50.9% | 2 | - | $6,596 | $577,120 | 34 | - | false | false |
| 20 | - | Save the Cinema | $12,864 | - | 40 | - | $321 | $12,864 | 1 | Altitude Film Entertainment | true | false |
| 21 | - | The Gruffalo's Child 2022 Re-release | $12,079 | - | 86 | - | $140 | $71,024 | - | - | - | false |
| 22 | 15 | No Time to Die | $11,901 | -67.3% | 42 | -59 | $283 | $132,149,938 | 16 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | Ron's Gone Wrong | $10,153 | -24.9% | 128 | -18 | $79 | $6,346,384 | 14 | Walt Disney Studios Motion Pictures | false | false |
| 24 | - | Thomas & Friends: Journey Beyond Sodor 2021 Re-release | $5,557 | - | 18 | - | $308 | $15,621 | 1 | National Amusements | true | false |
| 25 | - | Shooter | $5,041 | - | 15 | - | $336 | $5,041 | 1 | Rising Star Entertainment | true | false |
| 26 | 22 | The French Dispatch | $4,955 | +23.2% | 7 | +1 | $707 | $5,674,706 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 27 | - | Tosca - Roh, London 2021 (Opera) | $2,199 | - | 1 | - | $2,199 | $178,671 | 6 | - | false | false |
| 28 | - | Embrace Again | $2,143 | - | 11 | - | $194 | $2,143 | 1 | China Lion Film Distribution | true | false |
| 29 | - | The Snail and the Whale | $2,076 | - | 50 | - | $41 | $12,419 | 11 | - | false | false |
| 30 | - | Zog and the Flying Doctors | $1,712 | - | 62 | - | $27 | $10,972 | - | - | - | false |
| 31 | - | Anything Goes - The Musical (Theatre) | $1,007 | - | 1 | - | $1,007 | $1,061,477 | 8 | More2Screen | false | false |
| 32 | 34 | Spencer | $373 | -19.4% | 2 | -1 | $186 | $3,840,871 | 11 | STX Entertainment | false | false |
| 33 | - | Exhibition on Screen: The Danish Collector - Delacroix to Gauguin | $306 | - | 2 | - | $153 | $27,213 | 8 | Seventh Art Productions | false | false |
| 34 | 31 | Cliff Richard: The Great 80 Tour | $191 | -69.2% | 2 | +1 | $95 | $794,607 | 13 | - | false | false |
| 35 | 33 | Eternals | $156 | -73.3% | - | - | - | $19,955,942 | 11 | Walt Disney Studios Motion Pictures | false | false |
| 36 | - | The Most Reluctant Convert | $123 | - | 1 | - | $123 | $47,944 | 11 | More2Screen | false | false |
| 37 | - | Mothers of the Revolution | $98 | - | 1 | - | $98 | $98 | 1 | - | true | false |
