| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man: No Way Home | $2,815,608 | -35.3% | 672 | - | $4,189 | $39,267,468 | 5 | Sony Pictures Releasing | false | false |
| 2 | - | Scream | $880,757 | - | 452 | - | $1,948 | $993,763 | 1 | Paramount Pictures | true | false |
| 3 | 2 | The King's Man | $802,074 | -38.4% | 544 | - | $1,474 | $2,487,504 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 4 | 3 | House of Gucci | $621,707 | -27.1% | 596 | - | $1,043 | $9,929,795 | 7 | Universal Pictures | false | false |
| 5 | 4 | The Matrix Resurrections | $402,276 | -48.4% | 516 | - | $779 | $5,605,439 | 4 | Warner Bros. | false | false |
| 6 | 5 | Clifford the Big Red Dog | $330,257 | -36.9% | 593 | - | $556 | $3,344,014 | 7 | Paramount Pictures | false | false |
| 7 | - | Spencer | $263,284 | - | 222 | - | $1,185 | $337,057 | 1 | DCM Film Distribution | true | false |
| 8 | 6 | Encanto | $219,825 | -42.7% | 480 | - | $457 | $4,628,639 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 9 | 8 | Intersection: Glad to Have You Eren | $177,098 | -28.6% | 85 | - | $2,083 | $566,602 | 3 | AF-Media | false | false |
| 10 | - | School of Magical Animals | $129,424 | - | 389 | - | $332 | $11,819,991 | - | Andrea Leone Films | - | false |
| 11 | 7 | The 355 | $109,119 | -58% | 357 | - | $305 | $408,300 | 2 | - | false | false |
| 12 | 10 | No Time to Die | $79,597 | -46.8% | 231 | - | $344 | $71,900,490 | 16 | Universal Pictures International (UPI) | false | false |
| 13 | - | West Side Story | $70,650 | - | 223 | - | $316 | $1,270,340 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 14 | - | My Wonderful Wanda | $62,134 | - | 132 | - | $470 | $202,048 | 2 | Warner Bros. | false | false |
| 15 | - | Laura's Star | $58,405 | - | 498 | - | $117 | $1,100,358 | 6 | Warner Bros. | false | false |
| 16 | - | Venom: Let There Be Carnage | $46,421 | - | 103 | - | $450 | $12,228,738 | 13 | Sony Pictures Releasing | false | false |
| 17 | - | Respect | $36,202 | - | 96 | - | $377 | $819,896 | 8 | Universal Pictures | false | false |
| 18 | - | Ghostbusters: Afterlife | $33,316 | - | 143 | - | $232 | $3,026,712 | 9 | Sony Pictures Releasing | false | false |
| 19 | - | Pleasure | $29,444 | - | 46 | - | $640 | $31,560 | 1 | - | true | false |
| 20 | 11 | The French Dispatch | $18,046 | -21.8% | - | - | - | $2,255,246 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 21 | - | Delicious | $16,221 | - | 63 | - | $257 | $484,179 | 8 | Neue Visionen Filmverleih | false | false |
| 22 | 13 | Ron's Gone Wrong | $1,560 | -27.2% | - | - | - | $1,026,673 | 12 | Walt Disney Studios Motion Pictures | false | false |
| 23 | 12 | Eternals | $1,356 | -82.5% | - | - | - | $9,402,493 | 11 | Walt Disney Studios Motion Pictures | false | false |
| 24 | - | Heavens Above | $1,106 | - | 9 | - | $122 | $51,799 | 5 | Neue Visionen Filmverleih | false | false |
| 25 | - | Contra | $1,008 | - | 267 | - | $3 | $6,775,074 | 12 | Constantin Film | false | false |
| 26 | - | Tailor | $164 | - | 1 | - | $164 | $521,485 | 21 | Neue Visionen Filmverleih | false | false |
| 27 | - | Antlers | $106 | - | - | - | - | $245,905 | 12 | Walt Disney Studios Motion Pictures | false | false |
| 28 | - | Mama Weed | $32 | - | 1 | - | $32 | $1,512,494 | 67 | Neue Visionen Filmverleih | false | false |
