| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | West Side Story | $1,722,572 | - | 678 | - | $2,540 | $1,722,572 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Clifford the Big Red Dog | $1,716,690 | - | 567 | - | $3,027 | $1,716,690 | 1 | Paramount Pictures International | true | false |
| 3 | 1 | House of Gucci | $1,035,272 | -48.3% | 677 | -29 | $1,529 | $9,743,397 | 3 | Universal Pictures | false | false |
| 4 | 2 | Encanto | $843,359 | -50.2% | 599 | -15 | $1,407 | $5,598,420 | 3 | Walt Disney Studios Motion Pictures | false | false |
| 5 | 3 | Ghostbusters: Afterlife | $777,150 | -44.9% | 588 | -49 | $1,321 | $13,446,220 | 4 | Sony Pictures Releasing | false | false |
| 6 | 5 | Eternals | $202,449 | -52% | 345 | -119 | $586 | $19,602,726 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 7 | - | Home Alone 2020 Re-release | $163,259 | - | 313 | - | $521 | $903,435 | 55 | Park Circus | false | false |
| 8 | 6 | No Time to Die | $157,620 | -55.9% | 359 | -135 | $439 | $127,857,704 | 11 | Universal Pictures International (UPI) | false | false |
| 9 | 13 | Elf 2021 Re-release | $157,252 | +7% | 335 | +83 | $469 | - | 3 | Park Circus | false | false |
| 10 | 10 | A Boy Called Christmas | $148,709 | -15.4% | 207 | -19 | $718 | $602,385 | 3 | Altitude Film Entertainment | false | false |
| 11 | 7 | Resident Evil: Welcome to Raccoon City | $141,388 | -57.8% | 292 | -37 | $484 | $675,353 | 2 | Sony Pictures Releasing | false | false |
| 12 | - | Boxing Day | $137,198 | - | 375 | - | $365 | $703,269 | 2 | Warner Bros. | false | false |
| 13 | 8 | Dune: Part One | $125,480 | -60.6% | 222 | -151 | $565 | $28,804,796 | 8 | Warner Bros. | false | false |
| 14 | - | The Nutcracker - Roh, London 2021 (Ballet) | $119,067 | - | 130 | - | $915 | $542,825 | 2 | - | false | false |
| 15 | - | Sword Art Online: Progressive - Aria of a Starless Night | $85,761 | - | 150 | - | $571 | $85,761 | 1 | Sony Pictures Releasing | true | false |
| 16 | - | Harry Potter and the Deathly Hallows: Part 2 2020 Re-release | $80,997 | - | 254 | - | $318 | - | 75 | Warner Bros. | false | false |
| 17 | - | Lamb | $62,015 | - | 71 | - | $873 | $62,015 | 1 | MUBI | true | false |
| 18 | 34 | Harry Potter and the Half-Blood Prince 2020 Re-release | $42,543 | +413.4% | 182 | +111 | $233 | - | 73 | Warner Bros. | false | false |
| 19 | - | Harry Potter and the Deathly Hallows: Part 1 2020 Re-release | $41,447 | - | 253 | - | $163 | - | 76 | Warner Bros. | false | false |
| 20 | 15 | Venom: Let There Be Carnage | $30,612 | -55.5% | 124 | -61 | $246 | $23,927,624 | 9 | Sony Pictures Releasing | false | false |
| 21 | - | Chandigarh Kare Aashiqui | $28,353 | - | 31 | - | $914 | $28,353 | 1 | Cinestaan AA Distributors | true | false |
| 22 | 17 | The French Dispatch | $26,849 | -52.5% | 55 | -28 | $488 | $5,425,933 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 23 | 28 | Harry Potter and the Order of the Phoenix 2020 Re-release | $24,626 | +45.3% | 101 | -51 | $243 | - | 73 | Warner Bros. | false | false |
| 24 | - | Cbeebies Christmas Show 2021 | $16,813 | - | 124 | - | $135 | $163,586 | 2 | Modern Films | false | false |
| 25 | 25 | Spencer | $16,434 | -41.1% | 92 | -56 | $178 | $3,719,188 | 6 | STX Entertainment | false | false |
| 26 | 23 | Love Actually 2021 Re-release | $14,882 | -54.7% | 58 | -34 | $256 | - | 3 | Park Circus | false | false |
| 27 | 24 | Ron's Gone Wrong | $13,813 | -52.3% | 144 | -69 | $95 | $6,089,293 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 28 | 32 | Antarctica 3D: On the Edge | $11,680 | +1.3% | 2 | - | $5,840 | $459,066 | 29 | - | false | false |
| 29 | 46 | Arthur Christmas 2020 Re-release | $10,738 | +533.5% | 104 | +98 | $103 | - | 3 | Sony Pictures Releasing | false | false |
| 30 | 35 | Mothering Sunday | $9,173 | +18.2% | 16 | -12 | $573 | $635,897 | 5 | Lionsgate | false | false |
| 31 | - | Hope | $8,203 | - | 35 | - | $234 | $8,203 | 1 | Picturehouse Entertainment | true | false |
| 32 | 26 | Bing's Christmas & Other Stories | $6,747 | -68.1% | 98 | -8 | $68 | $65,885 | 55 | - | false | false |
| 33 | - | Spider-Man: Far from Home | $5,897 | - | 72 | - | $81 | $49,566,298 | 128 | Sony Pictures Releasing | false | false |
| 34 | - | Arsène Wenger: Invincible | $5,617 | - | 1 | - | $5,617 | $45,162 | 5 | Park Circus | false | false |
| 35 | 27 | Last Night in Soho | $4,364 | -74.5% | 10 | -51 | $436 | $3,073,231 | 7 | Universal Pictures International (UPI) | false | false |
| 36 | - | Timmy's Cinema Adventure: Christmas Edition | $4,054 | - | 77 | - | $52 | $23,285 | 3 | Vue Entertainment | false | false |
| 37 | - | Nativity! 2020 Re-release | $3,037 | - | 4 | - | $759 | - | 55 | Entertainment One | false | false |
| 38 | - | Paddington 2021 Re-release | $2,870 | - | 41 | - | $70 | - | 3 | Park Circus | false | false |
| 39 | 36 | Anita | $2,851 | -56.8% | 3 | -3 | $950 | $39,868 | 5 | CMC Pictures | false | false |
| 40 | 38 | Pirates | $2,331 | -62.6% | 12 | -37 | $194 | $125,025 | 3 | Picturehouse Entertainment | false | false |
| 41 | 33 | Silent Night | $2,280 | -79.1% | 9 | -35 | $253 | $24,257 | 2 | Altitude Film Entertainment | false | false |
| 42 | - | Peter Duncan's Cinderella | $1,950 | - | 32 | - | $60 | $3,265 | 2 | Jack Be Nimble | false | false |
| 43 | - | Hey Duggee At The Movies 2 | $1,363 | - | 40 | - | $34 | $98,864 | - | Vue Entertainment | - | false |
| 44 | - | Spiritwalker | $1,353 | - | 3 | - | $451 | $1,353 | 1 | Trinity Filmed Entertainment | true | false |
| 45 | - | Marjaney | $648 | - | 7 | - | $92 | $648 | 1 | Masala Life Films | true | false |
| 46 | - | The Storms of Jeremy Thomas | $628 | - | 6 | - | $104 | $628 | 1 | Curzon Film Distributors | true | false |
| 47 | - | Citizen Ashe | $300 | - | 2 | - | $150 | $300 | 1 | Periscoop Film | true | false |
| 48 | - | Exhibition on Screen: The Danish Collector - Delacroix to Gauguin | $70 | - | 1 | - | $70 | $23,650 | 3 | Seventh Art Productions | false | false |
