| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ghostbusters: Afterlife | $5,801,860 | - | 658 | - | $8,817 | $5,801,860 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Eternals | $1,636,970 | -58.2% | - | - | - | $17,282,139 | 3 | Walt Disney Studios Motion Pictures | false | false |
| 3 | 2 | No Time to Die | $1,264,221 | -39.9% | 626 | -52 | $2,019 | $127,069,895 | 8 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | Dune: Part One | $853,743 | -45.7% | 556 | -95 | $1,535 | $27,145,601 | 5 | Warner Bros. | false | false |
| 5 | - | King Richard | $766,966 | - | 559 | - | $1,372 | $766,966 | 1 | Roadshow Films | true | false |
| 6 | 5 | The Boss Baby: Family Business | $477,617 | -38% | 581 | -11 | $822 | $9,260,898 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Spencer | $409,541 | -56.3% | 629 | -19 | $651 | $3,177,255 | 3 | STX Entertainment | false | false |
| 8 | 6 | Venom: Let There Be Carnage | $377,324 | -46.3% | 339 | -109 | $1,113 | $23,665,397 | 6 | Sony Pictures Releasing | false | false |
| 9 | 8 | Ron's Gone Wrong | $245,406 | -33.9% | - | - | - | $6,126,303 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 10 | 7 | The Addams Family 2 | $233,268 | -48% | 513 | -42 | $454 | $13,600,278 | 7 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | The French Dispatch | $220,522 | -38.5% | - | - | - | $4,976,414 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 12 | - | Petite Maman | $130,878 | - | 68 | - | $1,924 | $130,878 | 1 | MUBI | true | false |
| 13 | 10 | Last Night in Soho | $130,593 | -46.3% | 218 | -122 | $599 | $2,890,814 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | - | Pitbull | $127,813 | - | 206 | - | $620 | $127,813 | 1 | Kinostar Filmverleih | true | false |
| 15 | 11 | Mothering Sunday | $74,605 | -64.6% | 151 | -19 | $494 | $462,293 | 2 | Lionsgate | false | false |
| 16 | - | The Battle at Lake Changjin | $63,392 | - | 45 | - | $1,408 | $63,392 | 1 | Trinity Filmed Entertainment | true | false |
| 17 | - | Drive My Car | $46,001 | - | 27 | - | $1,703 | $46,001 | 1 | Modern Films | true | false |
| 18 | - | Rocky IV 2021 Re-release (Ultimate Director's Cut) | $42,737 | - | 116 | - | $368 | $42,737 | 1 | Park Circus | true | false |
| 19 | - | Neon Genesis Evangelion: The End of Evangelion 2021 Re-release | $42,214 | - | 1 | - | $42,214 | $42,214 | 1 | National Amusements | true | false |
| 20 | - | Warning | $33,030 | - | 14 | - | $2,359 | $33,030 | 1 | Rising Star Entertainment | true | false |
| 21 | - | Bunty Aur Babli 2 | $28,332 | - | 20 | - | $1,416 | $28,332 | 1 | Yash Raj Films | true | false |
| 22 | 25 | Antarctica 3D: On the Edge | $13,249 | -6.4% | 2 | - | $6,624 | $420,066 | 26 | - | false | false |
| 23 | - | Tom & Jerry | $12,031 | - | 96 | - | $125 | $1,729,317 | 32 | Warner Bros. | false | false |
| 24 | - | Khel Khel Mein | $11,522 | - | 26 | - | $443 | $11,522 | 1 | - | true | false |
| 25 | - | Hey Duggee At The Movies 2 | $9,256 | - | 80 | - | $115 | $89,907 | - | Vue Entertainment | - | false |
| 26 | - | Breaking Out | $9,243 | - | 15 | - | $616 | $9,243 | 1 | Element Films | true | false |
| 27 | 16 | Harry Potter and the Sorcerer's Stone 2021 Re-release | $8,869 | -82.4% | 33 | -118 | $268 | - | 4 | Warner Bros. | false | false |
| 28 | 18 | Paani Ch Madhaani | $7,028 | -73.8% | 6 | -14 | $1,171 | $147,231 | 3 | Rising Star Entertainment | false | false |
| 29 | 23 | The Last Duel | $6,572 | -54.1% | 28 | -15 | $234 | $1,142,626 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 30 | - | The Snail and the Whale | $4,859 | - | 82 | - | $59 | $9,915 | 3 | - | false | false |
| 31 | - | Dennis And Gnasher: Unleashed! Operation Noise | $4,172 | - | 85 | - | $49 | $18,246 | 5 | - | false | false |
| 32 | 19 | The Most Reluctant Convert | $3,669 | -85.8% | 6 | -80 | $611 | $43,217 | 3 | More2Screen | false | false |
| 33 | 22 | Antlers | $3,306 | -77.5% | - | - | - | $622,831 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 34 | 20 | Arsène Wenger: Invincible | $3,098 | -83% | 5 | -1 | $619 | $33,616 | 2 | Park Circus | false | false |
| 35 | - | 42nd Street: The Musical | $2,887 | - | 1 | - | $2,887 | $1,956,425 | - | CinemaLive | - | false |
| 36 | 24 | Naked 4K - Restoration | $2,723 | -80.8% | 5 | - | $544 | $23,560 | 2 | British Film Institute (BFI) | false | false |
| 37 | 47 | Free Guy | $2,430 | +1,908.3% | - | - | - | $23,159,249 | 15 | Walt Disney Studios Motion Pictures | false | false |
| 38 | 36 | The Colour Room | $2,394 | -50.4% | 3 | -21 | $798 | $12,726 | 2 | Altitude Film Entertainment | false | false |
| 39 | 40 | Anita | $2,142 | -17.9% | 1 | - | $2,142 | $8,896 | 2 | CMC Pictures | false | false |
| 40 | 27 | Shang-Chi and the Legend of the Ten Rings | $1,811 | -83.7% | - | - | - | $29,318,191 | 12 | Walt Disney Studios Motion Pictures | false | false |
| 41 | - | Hitman's Wife's Bodyguard | $1,759 | - | 1 | - | $1,759 | $5,169,469 | 23 | Lionsgate | false | false |
| 42 | - | All or Nothing 2021 Re-release | $1,353 | - | 1 | - | $1,353 | - | 4 | StudioCanal UK | false | false |
| 43 | 34 | The Rescue | $1,347 | -76.7% | 5 | -7 | $269 | $93,129 | 4 | Periscoop Film | false | false |
| 44 | - | Peterloo | $1,319 | - | 1 | - | $1,319 | $1,806,845 | 160 | Entertainment One | false | false |
| 45 | 35 | Quant | $1,037 | -80.5% | 4 | -8 | $259 | $75,570 | 4 | - | false | false |
| 46 | - | Alien 2020 Re-release | $775 | - | 2 | - | $387 | - | 56 | Park Circus | false | false |
| 47 | - | The Courier | $724 | - | 1 | - | $724 | $2,710,463 | 15 | Lionsgate | false | false |
| 48 | - | Piano to Zanskar | $445 | - | 2 | - | $222 | $445 | 1 | - | true | false |
| 49 | 42 | The Last Bus | $315 | -83.9% | 18 | - | $17 | $597,376 | 13 | Parkland Pictures | false | false |
| 50 | - | Exhibition on Screen: Raphael Revealed | $274 | - | 1 | - | $274 | $25,917 | 7 | Seventh Art Productions | false | false |
| 51 | - | Nomadland | $207 | - | - | - | - | $3,016,870 | 27 | Walt Disney Pictures | false | false |
