| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Eternals | $3,914,938 | -46.8% | 649 | - | $6,032 | $14,179,981 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 2 | 2 | No Time to Die | $2,103,112 | -21.1% | 678 | - | $3,101 | $124,370,166 | 7 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | Dune: Part One | $1,573,270 | -24.7% | 651 | - | $2,416 | $25,408,755 | 4 | Warner Bros. | false | false |
| 4 | 5 | Spencer | $936,372 | +64.8% | 648 | +465 | $1,445 | $2,055,557 | 2 | STX Entertainment | false | false |
| 5 | 8 | The Boss Baby: Family Business | $770,247 | +841.4% | 592 | - | $1,301 | $8,688,396 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Venom: Let There Be Carnage | $703,112 | -22.2% | 448 | - | $1,569 | $22,926,178 | 5 | Sony Pictures Releasing | false | false |
| 7 | - | The Addams Family 2 | $448,259 | - | 555 | - | $807 | $13,289,565 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Ron's Gone Wrong | $371,115 | +2.3% | 562 | - | $660 | $5,731,465 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 9 | 6 | The French Dispatch | $358,404 | -21.3% | 268 | - | $1,337 | $4,551,470 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 10 | - | Last Night in Soho | $243,121 | - | 340 | - | $715 | $2,576,538 | 3 | Universal Pictures International (UPI) | false | false |
| 11 | - | Mothering Sunday | $210,516 | - | 170 | - | $1,238 | $210,516 | 1 | Lionsgate | true | false |
| 12 | - | Kurup | $177,304 | - | 76 | - | $2,332 | $177,304 | 1 | RFT Films | true | false |
| 13 | - | Sooryavanshi | $162,075 | - | 69 | - | $2,348 | $591,713 | 2 | Reliance Big Pictures | false | false |
| 14 | - | Wesele | $99,421 | - | 132 | - | $753 | $99,421 | 1 | Magnetes | true | false |
| 15 | - | Cry Macho | $96,755 | - | 341 | - | $283 | $96,755 | 1 | Warner Bros. | true | false |
| 16 | - | Harry Potter and the Sorcerer's Stone 2021 Re-release | $50,329 | - | 151 | - | $333 | $1,698,396 | 3 | Warner Bros. | false | false |
| 17 | - | Fuffad Ji | $33,996 | - | 45 | - | $755 | $33,996 | 1 | - | true | false |
| 18 | - | Paani Ch Madhaani | $26,834 | - | 20 | - | $1,341 | $127,666 | 2 | Rising Star Entertainment | false | false |
| 19 | - | The Most Reluctant Convert | $25,913 | - | 86 | - | $301 | $38,500 | 2 | More2Screen | false | false |
| 20 | - | Arsène Wenger: Invincible | $18,207 | - | 6 | - | $3,034 | $18,207 | 1 | Park Circus | true | false |
| 21 | - | Neon Genesis Evangelion: Death & Rebirth 2021 Re-release | $15,877 | - | 42 | - | $378 | $15,877 | 1 | National Amusements | true | false |
| 22 | 9 | Antlers | $14,704 | -66.1% | - | - | - | $611,855 | 3 | Walt Disney Studios Motion Pictures | false | false |
| 23 | 10 | The Last Duel | $14,309 | -16.2% | 43 | - | $332 | $1,106,708 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 24 | - | Naked 4K - Restoration | $14,164 | - | 5 | - | $2,832 | $14,164 | 1 | British Film Institute (BFI) | true | false |
| 25 | - | Antarctica 3D: On the Edge | $14,149 | - | 2 | - | $7,074 | $403,877 | 25 | - | false | false |
| 26 | - | West Side Story 2021 Re-release | $11,704 | - | 48 | - | $243 | $7,232 | 1 | Park Circus | true | false |
| 27 | 11 | Shang-Chi and the Legend of the Ten Rings | $11,112 | -20.6% | - | - | - | $29,312,170 | 11 | Walt Disney Studios Motion Pictures | false | false |
| 28 | - | Becoming Cousteau | $9,123 | - | 19 | - | $480 | $9,123 | 1 | Periscoop Film | true | false |
| 29 | - | Hey Duggee At The Movies 2 | $7,551 | - | 83 | - | $90 | $78,731 | - | Vue Entertainment | - | false |
| 30 | - | Natural Light | $7,541 | - | 12 | - | $628 | $7,541 | 1 | Curzon Film Distributors | true | false |
| 31 | - | South Wind 2: Speed Up | $6,460 | - | 8 | - | $807 | $6,460 | 1 | - | true | false |
| 32 | - | Zog and the Flying Doctors | $6,456 | - | 90 | - | $71 | $6,456 | - | - | - | false |
| 33 | - | Raging Fire | $6,117 | - | 27 | - | $226 | $6,117 | 1 | Trinity Filmed Entertainment | true | false |
| 34 | - | The Rescue | $5,792 | - | 12 | - | $482 | $85,661 | 3 | Periscoop Film | false | false |
| 35 | - | Quant | $5,331 | - | 12 | - | $444 | $63,011 | 3 | - | false | false |
| 36 | - | The Colour Room | $4,826 | - | 24 | - | $201 | $4,826 | 1 | Altitude Film Entertainment | true | false |
| 37 | - | Topsy-Turvy 2021 Re-release | $3,781 | - | 1 | - | $3,781 | $1,595,801 | 1 | Pathé | true | false |
| 38 | - | You Will Die at 20 | $3,431 | - | 6 | - | $571 | $3,431 | 1 | New Wave Films | true | false |
| 39 | - | Bull | $2,877 | - | 29 | - | $99 | $17,426 | 2 | Signature Entertainment | false | false |
| 40 | - | Anita | $2,610 | - | 1 | - | $2,610 | $6,754 | 1 | CMC Pictures | true | false |
| 41 | - | Keyboard Fantasies | $2,321 | - | 7 | - | $331 | $2,321 | 1 | Modern Films | true | false |
| 42 | 13 | The Last Bus | $1,953 | +1,475% | 18 | - | $108 | $589,145 | 12 | Parkland Pictures | false | false |
| 43 | - | The Pebble and the Boy | $1,945 | - | 1 | - | $1,945 | $137,230 | 12 | Munro Films | false | false |
| 44 | - | Through the Night | $368 | - | 2 | - | $184 | $368 | 1 | Together Films | true | false |
| 45 | - | National Theatre Live: Follies 2021 Re-release | $343 | - | 1 | - | $343 | $286,782 | 12 | National Theatre | false | false |
| 46 | - | Volcano | $168 | - | 2 | - | $84 | $168 | 1 | N/A | true | false |
| 47 | 14 | Free Guy | $121 | +30.1% | - | - | - | $23,156,695 | 14 | Walt Disney Studios Motion Pictures | false | false |
| 48 | 12 | Jungle Cruise | $47 | -93.8% | - | - | - | $17,361,566 | 16 | Walt Disney Studios Motion Pictures | false | false |
