| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Venom: Let There Be Carnage | $1,646,440 | - | 670 | - | $2,457 | $6,520,713 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Halloween Kills | $637,535 | - | 357 | - | $1,785 | $637,535 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | No Time to Die | $487,340 | - | 319 | - | $1,527 | $7,781,700 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | - | The Addams Family 2 | $470,774 | - | 337 | - | $1,396 | $3,208,052 | 3 | Universal Pictures | false | false |
| 5 | - | The Good Boss | $442,555 | - | 309 | - | $1,432 | $1,258,983 | 2 | Miramax | false | false |
| 6 | - | Ron's Gone Wrong | $380,155 | - | 435 | - | $873 | $380,155 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 7 | 1 | Parallel Mothers | $254,571 | -37.4% | 355 | -36 | $717 | $2,249,386 | 3 | Sony Pictures Releasing | false | false |
| 8 | - | The French Dispatch | $251,698 | - | 205 | - | $1,227 | $251,698 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 9 | - | Dune: Part One | $223,026 | - | 346 | - | $644 | $8,832,478 | 6 | Warner Bros. | false | false |
| 10 | - | Maixabel | $130,826 | - | 186 | - | $703 | $2,702,995 | 5 | Walt Disney Pictures | false | false |
| 11 | - | The Laws of the Border | $52,129 | - | 224 | - | $232 | $690,698 | 3 | Warner Bros. | false | false |
| 12 | - | Don't Breathe 2 | $49,116 | - | 124 | - | $396 | $1,971,860 | 5 | Sony Pictures Releasing | false | false |
| 13 | - | PAW Patrol: The Movie | $45,578 | - | 155 | - | $294 | $3,294,276 | 9 | Paramount Pictures | false | false |
| 14 | - | España, la primera globalización | $42,845 | - | 61 | - | $702 | $149,419 | 2 | - | false | false |
| 15 | - | Supernova | $32,095 | - | 83 | - | $386 | $32,382 | 1 | Wanda Visión S.A. | true | false |
| 16 | - | The Rose Maker | $29,567 | - | 56 | - | $527 | $29,567 | 1 | BTeam Pictures | true | false |
| 17 | - | ¡A todo tren! Destino Asturias | $26,473 | - | 61 | - | $433 | $9,823,380 | 16 | Warner Bros. | false | false |
| 18 | - | Medjugorje, la película | $19,061 | - | 50 | - | $381 | $273,906 | 4 | - | false | false |
| 19 | - | Terremoto | $17,809 | - | 37 | - | $481 | $488,287 | 4 | - | false | false |
| 20 | - | Titane | $17,441 | - | 48 | - | $363 | $230,390 | 3 | Caramel Films | false | false |
| 21 | 2 | Shang-Chi and the Legend of the Ten Rings | $17,358 | -63.7% | 54 | - | $321 | $6,601,767 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 22 | - | Family Swap | $10,006 | - | 43 | - | $232 | $818,538 | 7 | DeAPlaneta | false | false |
| 23 | - | Claret | $8,094 | - | 14 | - | $578 | $73,838 | 5 | - | false | false |
| 24 | - | The Boss Baby: Family Business | $7,235 | - | 39 | - | $185 | $5,174,056 | 12 | Universal Pictures International (UPI) | false | false |
| 25 | - | Cry Macho | $5,917 | - | 22 | - | $268 | $836,029 | 5 | Warner Bros. | false | false |
| 26 | - | Who's Stopping Us | $4,010 | - | 15 | - | $267 | $4,010 | - | Atalanta Filmes | - | false |
| 27 | - | Dogtanian and the Three Muskehounds | $3,469 | - | 30 | - | $115 | $1,356,994 | 8 | A Contracorriente Films | false | false |
| 28 | 3 | Free Guy | $2,599 | -54.3% | - | - | - | $3,609,986 | 10 | Walt Disney Pictures | false | false |
| 29 | - | Wojtyla. La investigación | $1,843 | - | 1 | - | $1,843 | $2,328 | 1 | - | true | false |
| 30 | - | Vivo | $1,578 | - | 2 | - | $789 | $274,099 | - | Bosco Films | - | false |
| 31 | - | Zutik | $1,446 | - | 14 | - | $103 | $1,446 | 1 | Filmax | true | false |
| 32 | - | Sevillanas de Brooklyn | $758 | - | 2 | - | $379 | $126,310 | 6 | Filmax | false | false |
| 33 | - | Chavalas | $701 | - | 4 | - | $175 | $275,898 | 8 | Filmax | false | false |
| 34 | - | Nur eta herensugearen tenplua 2021 Re-release | $688 | - | 5 | - | $137 | $5,483 | 20 | Barton Films | false | false |
| 35 | 4 | Jungle Cruise | $638 | -81.5% | - | - | - | $4,077,008 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 36 | - | Strange Voyage 2021 Re-release | $423 | - | 3 | - | $141 | $746 | 1 | A Contracorriente Films | true | false |
| 37 | - | Garcia & Garcia | $384 | - | 3 | - | $128 | $1,133,254 | 9 | A Contracorriente Films | false | false |
| 38 | - | The Day of the Beast 2021 Re-release | $266 | - | 4 | - | $66 | $9,775 | 2 | Con Un Pack Distribución | false | false |
| 39 | - | Nora | $163 | - | 1 | - | $163 | $65,505 | 8 | Sherlock Films | false | false |
| 40 | 6 | Black Widow | $122 | -29.1% | - | - | - | $7,329,424 | 16 | Walt Disney Pictures | false | false |
| 41 | - | Negro Purpura | $87 | - | 1 | - | $87 | $10,370 | 5 | - | false | false |
| 42 | - | Callejeras | $71 | - | 1 | - | $71 | $1,378 | 1 | - | true | false |
| 43 | - | Yesterday's Two Nights | $65 | - | 1 | - | $65 | $12,889 | 33 | Splendor Films | false | false |
| 44 | - | Aztarnak - Huellas | $57 | - | 2 | - | $28 | $2,361 | 2 | Barton Films | false | false |
