| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Dune: Part One | $1,434,330 | -41.7% | 370 | -376 | $3,876 | $4,847,710 | 2 | Warner Bros. | false | false |
| 2 | - | Maixabel | $521,633 | - | 364 | - | $1,433 | $521,633 | 1 | Walt Disney Pictures | true | false |
| 3 | - | Don't Breathe 2 | $471,167 | - | 315 | - | $1,495 | $471,167 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Shang-Chi and the Legend of the Ten Rings | $368,465 | -35% | 305 | - | $1,208 | $5,589,177 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 5 | - | Cry Macho | $279,754 | - | 277 | - | $1,009 | $279,754 | 1 | Warner Bros. | true | false |
| 6 | - | PAW Patrol: The Movie | $222,296 | - | 317 | - | $701 | $2,599,218 | 5 | Paramount Pictures | false | false |
| 7 | - | Family Swap | $115,019 | - | 184 | - | $625 | $523,093 | 3 | DeAPlaneta | false | false |
| 8 | - | The Boss Baby: Family Business | $103,359 | - | 195 | - | $530 | $4,948,292 | 8 | Universal Pictures International (UPI) | false | false |
| 9 | - | ¡A todo tren! Destino Asturias | $97,383 | - | 131 | - | $743 | $9,500,086 | 12 | Warner Bros. | false | false |
| 10 | - | Malignant | $94,543 | - | 253 | - | $373 | $1,977,069 | 4 | Warner Bros. | false | false |
| 11 | - | After We Fell | $81,033 | - | 239 | - | $339 | $2,696,955 | 4 | Diamond Films | false | false |
| 12 | - | Respect | $73,891 | - | 140 | - | $527 | $73,891 | 1 | Universal Pictures | true | false |
| 13 | 3 | Free Guy | $73,374 | -36.5% | 144 | - | $509 | $3,263,483 | 6 | Walt Disney Pictures | false | false |
| 14 | - | Dogtanian and the Three Muskehounds | $37,602 | - | 126 | - | $298 | $1,271,300 | 4 | A Contracorriente Films | false | false |
| 15 | - | Space Jam: A New Legacy | $35,258 | - | 41 | - | $859 | $5,051,297 | 10 | Warner Bros. | false | false |
| 16 | - | Garcia & Garcia | $33,669 | - | 103 | - | $326 | $1,084,099 | 5 | A Contracorriente Films | false | false |
| 17 | - | Old | $25,612 | - | 74 | - | $346 | $5,626,313 | 9 | Universal Pictures | false | false |
| 18 | - | Claret | $21,617 | - | 39 | - | $554 | $23,490 | 1 | - | true | false |
| 19 | - | Bye Bye Morons | $21,105 | - | 57 | - | $370 | $193,797 | 3 | - | false | false |
| 20 | - | Checkered Ninja 2 | $20,536 | - | 135 | - | $152 | $86,583 | 2 | - | false | false |
| 21 | 4 | Jungle Cruise | $20,091 | -24.5% | 28 | - | $717 | $3,723,775 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 22 | - | Escape Room: Tournament of Champions | $19,593 | - | 52 | - | $376 | $2,020,680 | 7 | Sony Pictures Releasing | false | false |
| 23 | - | The Suicide Squad | $16,983 | - | 72 | - | $235 | $5,316,600 | 8 | Warner Bros. | false | false |
| 24 | - | Sevillanas de Brooklyn | $16,462 | - | 100 | - | $164 | $96,192 | 2 | Filmax | false | false |
| 25 | - | Chavalas | $14,957 | - | 30 | - | $498 | $232,793 | 4 | Filmax | false | false |
| 26 | - | Descarrilados | $5,223 | - | 27 | - | $193 | $1,152,429 | 6 | Sony Pictures Releasing | false | false |
| 27 | - | The Unemployment Club | $5,021 | - | 66 | - | $76 | $54,338 | 2 | Vértice 360 | false | false |
| 28 | - | Nora | $3,259 | - | 8 | - | $407 | $56,347 | 4 | Sherlock Films | false | false |
| 29 | - | The Consequences | $2,962 | - | 25 | - | $118 | $24,810 | 2 | Syldavia Cinema | false | false |
| 30 | - | Negro Purpura | $2,530 | - | 8 | - | $316 | $2,771 | 1 | - | true | false |
| 31 | - | Undercover Wedding Crashers | $2,113 | - | 13 | - | $162 | $3,915,204 | 14 | Walt Disney Pictures | false | false |
| 32 | - | Con quién viajas | $1,994 | - | 18 | - | $110 | $140,572 | 3 | A Contracorriente Films | false | false |
| 33 | 5 | Nomadland | $1,137 | -44.9% | - | - | - | $2,742,353 | 27 | Walt Disney Pictures | false | false |
| 34 | 6 | Black Widow | $832 | -48.5% | - | - | - | $7,326,676 | 12 | Walt Disney Pictures | false | false |
| 35 | - | Un tiempo precioso | $696 | - | 1 | - | $696 | $1,115 | 1 | - | true | false |
| 36 | - | The Cover | $380 | - | 1 | - | $380 | $85,481 | 10 | Entertainment One | false | false |
| 37 | - | More the Merrier | $135 | - | 1 | - | $135 | $252,682 | 9 | Filmax | false | false |
| 38 | - | Billy | $113 | - | 2 | - | $56 | $4,083 | 2 | - | false | false |
| 39 | - | Dancing Beethoven 2021 Re-release | $61 | - | 1 | - | $61 | $10,815 | 1 | - | true | false |
| 40 | - | Ama | $6 | - | 1 | - | $6 | $25,620 | 11 | Filmax | false | false |
