| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Jungle Cruise | $35,018,731 | - | 4,310 | - | $8,124 | $35,018,731 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 2 | 1 | Old | $6,862,425 | -59.3% | 3,379 | +24 | $2,030 | $30,715,680 | 2 | Universal Pictures | false | false |
| 3 | - | The Green Knight | $6,790,917 | - | 2,790 | - | $2,434 | $6,790,917 | 1 | A24 | true | false |
| 4 | 3 | Black Widow | $6,471,183 | -44.3% | 3,360 | -890 | $1,925 | $167,112,045 | 4 | Walt Disney Studios Motion Pictures | false | false |
| 5 | - | Stillwater | $5,188,150 | - | 2,531 | - | $2,049 | $5,188,150 | 1 | Focus Features | true | false |
| 6 | 4 | Space Jam: A New Legacy | $4,325,673 | -54.8% | 3,501 | -501 | $1,235 | $63,170,781 | 3 | Warner Bros. | false | false |
| 7 | 2 | Snake Eyes | $4,064,394 | -69.6% | 3,540 | +19 | $1,148 | $22,346,938 | 2 | Paramount Pictures | false | false |
| 8 | 5 | F9: The Fast Saga | $2,663,925 | -44.7% | 2,348 | -502 | $1,134 | $168,558,540 | 6 | Universal Pictures | false | false |
| 9 | 6 | Escape Room: Tournament of Champions | $2,236,652 | -36.4% | 2,086 | -729 | $1,072 | $20,588,384 | 3 | Sony Pictures Releasing | false | false |
| 10 | 7 | The Boss Baby 2: Family Business | $1,377,390 | -51.8% | 1,865 | -908 | $738 | $53,544,630 | 5 | Universal Pictures | false | false |
| 11 | 8 | The Forever Purge | $1,143,285 | -52% | 1,166 | -947 | $980 | $42,722,600 | 5 | Universal Pictures | false | false |
| 12 | 9 | A Quiet Place Part II | $615,779 | -48.9% | 779 | -618 | $790 | $158,786,309 | 10 | Paramount Pictures | false | false |
| 13 | 10 | Roadrunner: A Film About Anthony Bourdain | $365,995 | -58.4% | 537 | -417 | $681 | $4,596,150 | 3 | Focus Features | false | false |
| 14 | 13 | Cruella | $340,242 | -32% | 235 | -260 | $1,447 | $85,386,628 | 10 | Walt Disney Studios Motion Pictures | false | false |
| 15 | 12 | Pig | $240,812 | -59% | 336 | -252 | $716 | $2,652,024 | 3 | Neon | false | false |
| 16 | 11 | Joe Bell | $178,495 | -76.2% | 1,053 | -41 | $169 | $1,273,939 | 2 | Roadside Attractions | false | false |
| 17 | 14 | Hitman's Wife's Bodyguard | $156,391 | -50.6% | 260 | -216 | $601 | $37,741,397 | 7 | Lionsgate | false | false |
| 18 | 16 | In the Heights | $109,805 | -43.5% | 191 | -114 | $574 | $29,807,206 | 8 | Warner Bros. | false | false |
| 19 | 15 | Peter Rabbit 2: The Runaway | $84,516 | -68.2% | 180 | -398 | $469 | $40,275,345 | 8 | Sony Pictures Releasing | false | false |
| 20 | - | The Conjuring: The Devil Made Me Do It | $70,999 | - | 100 | - | $709 | $65,213,224 | 9 | Warner Bros. | false | false |
| 21 | 18 | Zola | $55,262 | -53.8% | 114 | -115 | $484 | $4,728,044 | 5 | A24 | false | false |
| 22 | 19 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $51,975 | -50.2% | 85 | -65 | $611 | $2,199,756 | 6 | Searchlight Pictures | false | false |
| 23 | 25 | Raya and the Last Dragon | $26,202 | -11.4% | 30 | -5 | $873 | $54,690,803 | 22 | Walt Disney Studios Motion Pictures | false | false |
| 24 | 21 | 12 Mighty Orphans | $25,350 | -57.7% | 50 | -24 | $507 | $3,485,618 | 8 | Sony Pictures Releasing | false | false |
| 25 | 22 | Spirit Untamed | $21,825 | -44.9% | 738 | -157 | $29 | $17,620,410 | 9 | Universal Pictures | false | false |
| 26 | 24 | Once I Was Engaged | $17,345 | -50.9% | 28 | -4 | $619 | $139,039 | 2 | Excel Entertainment | false | false |
| 27 | - | Nine Days | $15,700 | - | 4 | - | $3,925 | $15,700 | 1 | Sony Pictures Classics | true | false |
| 28 | 26 | Queen Bees | $15,605 | -43.2% | 47 | -36 | $332 | $1,882,488 | 8 | Gravitas Ventures | false | false |
| 29 | 34 | Without Getting Killed or Caught | $14,430 | +127.2% | 7 | +6 | $2,061 | $23,893 | 2 | mTuckman Media | false | true |
| 30 | 29 | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $9,069 | -25.5% | 21 | -3 | $431 | $49,493,745 | 15 | FUNimation Entertainment | false | false |
| 31 | 38 | The Truffle Hunters | $8,694 | +58% | 14 | +2 | $621 | $516,087 | 22 | Sony Pictures Classics | false | false |
| 32 | 28 | Settlers | $8,646 | -33.7% | 7 | -23 | $1,235 | $24,471 | 2 | IFC Films | false | false |
| 33 | 30 | Witnesses | $5,787 | -47% | 12 | -5 | $482 | $815,871 | 9 | Purdie Distribution | false | false |
| 34 | 27 | Ailey | $4,857 | -67.8% | 2 | - | $2,428 | $26,402 | 2 | Neon | false | false |
| 35 | - | Enemies of the State | $4,142 | - | 13 | - | $318 | $4,142 | 1 | IFC Films | true | false |
| 36 | 40 | The Swimming Pool 2021 Re-release | $2,948 | -40.4% | 3 | - | $982 | $140,812 | 12 | Rialto Distribution | false | false |
| 37 | - | Never Gonna Snow Again | $2,828 | - | 5 | - | $565 | $2,828 | 1 | Kino Lorber | true | false |
| 38 | 41 | The Loneliest Whale: The Search for 52 | $2,742 | -40.7% | 20 | - | $137 | $102,354 | 4 | Bleecker Street Media | false | false |
| 39 | 33 | Mandibles | $2,500 | -66% | 14 | -7 | $178 | $16,279 | 2 | Magnet Releasing | false | false |
| 40 | 32 | I Carry You with Me | $2,322 | -72.1% | 18 | -26 | $129 | $162,258 | 6 | Sony Pictures Classics | false | false |
| 41 | 44 | Mama Weed | $2,270 | -26.9% | 8 | -2 | $283 | $23,851 | 3 | Music Box Films | false | false |
| 42 | 49 | Casanova, Last Love | $2,051 | +26.1% | 6 | +2 | $341 | $8,565 | 3 | Cohen Media Group | false | false |
| 43 | 39 | Werewolves Within | $1,779 | -67% | 11 | -6 | $161 | $573,563 | 6 | IFC Films | false | false |
| 44 | 43 | Dream Horse | $878 | -77.7% | 17 | - | $51 | $2,865,187 | 11 | Bleecker Street Media | false | false |
| 45 | 54 | The Dry | $453 | +10% | 2 | -1 | $226 | $364,023 | 11 | IFC Films | false | false |
| 46 | 45 | Can You Bring It: Bill T. Jones and D-Man in the Waters | $357 | -87% | 3 | -4 | $119 | $7,846 | 3 | Kino Lorber | false | false |
| 47 | 50 | The Ladykillers 2021 Re-release | $265 | -81.1% | 1 | -2 | $265 | $21,905 | 9 | Rialto Pictures | false | false |
| 48 | 31 | Secret Agent Dingledorf and His Trusty Dog Splat | $200 | -97.7% | 3 | -27 | $66 | $13,500 | 5 | Integrity Releasing | false | false |
| 49 | 42 | The Red Circle 2021 Re-release | $121 | -97.1% | 1 | -3 | $121 | $57,722 | 6 | Rialto Pictures | false | false |
| 50 | 51 | Summer of 85 | $93 | -92.3% | 2 | -3 | $46 | $70,580 | 7 | Music Box Films | false | false |
| 51 | 58 | The Perfect Candidate | $60 | +7.1% | 1 | - | $60 | $28,780 | 12 | Music Box Films | false | false |
| 52 | 59 | Shiva Baby | $32 | - | 1 | - | $32 | $156,734 | 18 | Utopia | false | false |
