| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Black Widow | $2,479,374 | -73.6% | 649 | - | $3,820 | $15,430,903 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 2 | - | Space Jam: A New Legacy | $1,877,142 | - | 603 | - | $3,113 | $1,877,142 | 1 | Warner Bros. | true | false |
| 3 | - | The Forever Purge | $991,233 | - | 501 | - | $1,978 | $991,233 | 1 | Universal Pictures | true | false |
| 4 | - | The Croods: A New Age | $958,925 | - | 602 | - | $1,592 | $958,925 | 1 | Universal Pictures | true | false |
| 5 | 2 | F9: The Fast Saga | $614,160 | -59.7% | 537 | -57 | $1,143 | $19,476,388 | 4 | Universal Pictures | false | false |
| 6 | - | Escape Room: Tournament of Champions | $382,843 | - | 414 | - | $924 | $382,843 | 1 | Sony Pictures Releasing | true | false |
| 7 | 3 | Peter Rabbit 2: The Runaway | $122,523 | -83.9% | 474 | -133 | $258 | $25,627,669 | 9 | Sony Pictures Releasing | false | false |
| 8 | 5 | In the Heights | $95,204 | -70.5% | 270 | -242 | $352 | $5,695,123 | 5 | Warner Bros. | false | false |
| 9 | - | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $86,126 | - | 131 | - | $657 | $86,126 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 10 | 6 | Cruella | $70,154 | -76.5% | 299 | - | $234 | $12,437,731 | 8 | Walt Disney Studios Motion Pictures | false | false |
| 11 | 8 | The Conjuring: The Devil Made Me Do It | $67,506 | -62.1% | 192 | -67 | $351 | $12,781,553 | 8 | Warner Bros. | false | false |
| 12 | 10 | Another Round | $58,687 | -56.9% | 127 | -39 | $462 | $777,680 | 3 | StudioCanal | false | false |
| 13 | 7 | Hitman's Wife's Bodyguard | $47,603 | -73.5% | 177 | -146 | $268 | $5,030,548 | 5 | Lionsgate | false | false |
| 14 | - | Deerskin | $33,857 | - | 61 | - | $555 | $33,857 | 1 | Picturehouse Entertainment | true | false |
| 15 | - | Nowhere Special | $30,308 | - | 83 | - | $365 | $30,308 | 1 | Curzon Film Distributors | true | false |
| 16 | 14 | Supernova | $14,872 | -66.7% | 72 | -133 | $206 | $949,884 | 4 | StudioCanal UK | false | false |
| 17 | 13 | The Father | $13,426 | -70.5% | 70 | -105 | $191 | $2,720,028 | 6 | Lionsgate | false | false |
| 18 | 11 | Tom & Jerry | $12,972 | -81.9% | 228 | +2 | $56 | $1,481,399 | 14 | Warner Bros. | false | false |
| 19 | 16 | Raya and the Last Dragon | $8,206 | -63.8% | - | - | - | $1,125,877 | 9 | Walt Disney Pictures | false | false |
| 20 | - | Two of Us | $4,660 | - | 14 | - | $332 | $4,660 | 1 | Peccadillo Pictures | true | false |
| 21 | 21 | Dream Horse | $3,783 | -43.8% | 22 | -29 | $171 | $959,009 | 7 | Warner Bros. | false | false |
| 22 | - | The Birthday Cake | $2,366 | - | 9 | - | $262 | $2,366 | 1 | Signature Entertainment | true | false |
| 23 | - | The Witches of the Orient | $1,967 | - | 7 | - | $281 | $1,967 | 1 | Modern Films | true | false |
| 24 | 50 | Six Minutes to Midnight | $1,944 | +727.2% | 4 | +3 | $486 | $56,304 | 17 | Lionsgate | false | false |
| 25 | 43 | Timmy's Cinema Adventure | $1,799 | +307% | 74 | +65 | $24 | $84,464 | 48 | Vue Entertainment | false | false |
| 26 | 40 | Ammonite | $1,370 | +102.7% | 4 | +1 | $342 | $253,080 | 9 | Lionsgate | false | false |
| 27 | 35 | The Reason I Jump | $1,368 | -22.7% | 5 | -7 | $273 | $88,027 | 5 | Picturehouse Entertainment | false | false |
| 28 | 36 | After Love | $1,360 | -21.8% | 5 | +2 | $272 | $152,470 | 7 | British Film Institute (BFI) | false | false |
| 29 | 18 | Bing's Animal Stories | $1,320 | -89.9% | 48 | -51 | $27 | $41,100 | 3 | Vue Entertainment | false | false |
| 30 | - | Peppa Pig: My First Cinema Experience 2020 Re-release | $1,158 | - | 16 | - | $72 | $373,512 | 42 | Entertainment One | false | false |
| 31 | - | Gosford Park | $1,060 | - | 1 | - | $1,060 | $16,948,417 | 1,016 | Entertainment Studios Motion Pictures | false | false |
| 32 | 53 | Sexy Beast 2021 Re-release | $995 | +3,880% | 25 | +24 | $39 | - | 3 | Park Circus | false | false |
| 33 | 33 | In the Earth | $958 | -57.8% | 15 | +7 | $63 | $212,199 | 5 | Universal Pictures | false | false |
| 34 | 46 | Don't Go Gentle: A Film About Idles | $859 | +164.3% | 3 | - | $286 | $18,029 | 3 | - | false | false |
| 35 | - | Branagh Theatre Live: Romeo and Juliet 2021 Re-release | $807 | - | 3 | - | $269 | - | 1 | More2Screen | true | false |
| 36 | 32 | To Be Someone | $614 | -77% | 8 | -5 | $76 | $5,856 | 2 | Kaleidoscope | false | false |
| 37 | - | Last Man Standing 2021 Re-release | $596 | - | 2 | - | $298 | $33,391 | 3 | Periscoop Film | false | false |
| 38 | 47 | Brassed Off 2021 Re-release | $460 | +89.3% | 5 | -7 | $92 | $5,447 | 3 | Park Circus | false | false |
| 39 | - | Bhaji on the Beach 2021 Re-release | $417 | - | 10 | - | $41 | $993 | 3 | Park Circus | false | false |
| 40 | 42 | The Witches | $394 | -19.3% | 3 | +2 | $131 | $37,548 | 14 | Warner Bros. | false | false |
| 41 | - | Akram Khan's Giselle | $297 | - | 1 | - | $297 | $165,957 | 5 | Trafalgar Releasing | false | false |
| 42 | - | Exhibition on Screen: Sunflowers | $286 | - | 2 | - | $143 | $13,923 | 7 | Seventh Art Productions | false | false |
| 43 | - | Matthew Bourne's Cinderella | $282 | - | 1 | - | $282 | $184,752 | 1 | More2Screen | true | false |
| 44 | - | Rare Beasts | $260 | - | 2 | - | $130 | $61,492 | 9 | - | false | false |
| 45 | 39 | Lady Boss: The Jackie Collins Story | $187 | -73.5% | 3 | - | $62 | $19,733 | 3 | Modern Films | false | false |
| 46 | 37 | Local Hero 2021 Re-release | $124 | -85.8% | 2 | -2 | $62 | $5,871 | 3 | Park Circus | false | false |
| 47 | 24 | Dennis & Gnasher: Unleashed! On the Big Screen | $12 | -99.7% | 1 | -72 | $12 | $61,582 | 39 | - | false | false |
