| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | F9: The Fast Saga | $29,101,290 | - | 4,203 | - | $6,923 | $122,205,250 | 2 | Universal Pictures | false | false |
| 2 | - | The Boss Baby: Family Business | $19,652,550 | - | 3,644 | - | $5,393 | $19,652,550 | 1 | Universal Pictures | true | false |
| 3 | - | The Forever Purge | $15,762,605 | - | 3,051 | - | $5,166 | $15,762,605 | 1 | Universal Pictures | true | false |
| 4 | - | A Quiet Place Part II | $5,374,942 | - | 2,826 | - | $1,901 | $145,586,601 | 6 | Paramount Pictures | false | false |
| 5 | - | Hitman's Wife's Bodyguard | $3,868,519 | - | 3,361 | - | $1,151 | $32,246,686 | 3 | Lionsgate | false | false |
| 6 | - | Cruella | $3,154,237 | - | 2,380 | - | $1,325 | $77,193,221 | 6 | Walt Disney Studios Motion Pictures | false | false |
| 7 | - | Peter Rabbit 2: The Runaway | $2,838,439 | - | 2,954 | - | $960 | $35,004,921 | 4 | Sony Pictures Releasing | false | false |
| 8 | - | The Conjuring: The Devil Made Me Do It | $1,618,438 | - | 1,716 | - | $943 | $62,554,101 | 5 | Warner Bros. | false | false |
| 9 | - | Zola | $1,552,095 | - | 1,468 | - | $1,057 | $2,349,347 | 1 | A24 | true | false |
| 10 | - | In the Heights | $1,538,965 | - | 1,405 | - | $1,095 | $27,150,989 | 4 | Warner Bros. | false | false |
| 11 | - | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | $802,054 | - | 752 | - | $1,066 | $802,054 | 2 | Searchlight Pictures | false | false |
| 12 | - | Spirit Untamed | $446,695 | - | 1,296 | - | $344 | $17,003,250 | 5 | Universal Pictures | false | false |
| 13 | - | 12 Mighty Orphans | $335,495 | - | 338 | - | $992 | $2,920,856 | 4 | Sony Pictures Releasing | false | false |
| 14 | - | Nobody | $295,925 | - | 224 | - | $1,321 | $27,214,710 | 15 | Universal Pictures | false | false |
| 15 | - | The House Next Door: Meet the Blacks 2 | $110,390 | - | 116 | - | $951 | $2,792,274 | 4 | Hidden Empire Film Group (HEFG) | false | false |
| 16 | - | Queen Bees | $108,804 | - | 170 | - | $640 | $1,546,218 | 4 | Gravitas Ventures | false | false |
| 17 | - | Werewolves Within | $108,527 | - | 209 | - | $519 | $466,344 | 2 | IFC Films | false | false |
| 18 | - | Demon Slayer: Kimetsu no Yaiba - The Movie: Mugen Train | $81,459 | - | 81 | - | $1,005 | $49,299,762 | 11 | FUNimation Entertainment | false | false |
| 19 | - | Wrath of Man | $62,978 | - | 82 | - | $768 | $27,411,424 | 9 | United Artists Releasing | false | false |
| 20 | - | Witnesses | $53,366 | - | 33 | - | $1,617 | $691,911 | 5 | Purdie Distribution | false | false |
| 21 | - | Raya and the Last Dragon | $48,503 | - | 75 | - | $646 | $54,545,246 | 18 | Walt Disney Studios Motion Pictures | false | false |
| 22 | - | The Sparks Brothers | $34,800 | - | 130 | - | $267 | $625,720 | 3 | Focus Features | false | false |
| 23 | - | Spiral | $29,719 | - | 102 | - | $291 | $23,206,996 | 8 | Lionsgate | false | false |
| 24 | - | I Carry You with Me | $27,856 | - | 24 | - | $1,160 | $51,406 | 2 | Sony Pictures Classics | false | false |
| 25 | - | Dream Horse | $19,847 | - | 73 | - | $271 | $2,812,094 | 7 | Bleecker Street Media | false | false |
| 26 | - | Rita Moreno: Just a Girl Who Decided to Go for It | $19,219 | - | 56 | - | $343 | $237,572 | 3 | Roadside Attractions | false | false |
| 27 | - | The Truffle Hunters | $17,688 | - | 25 | - | $707 | $462,308 | 18 | Sony Pictures Classics | false | false |
| 28 | - | The God Committee | $16,926 | - | 28 | - | $604 | $16,926 | 1 | Vertical Entertainment | true | false |
| 29 | - | Lansky | $16,438 | - | 42 | - | $391 | $56,208 | 2 | Vertical Entertainment | false | false |
| 30 | - | Truman & Tennessee: An Intimate Conversation | $10,202 | - | 21 | - | $485 | $43,175 | 3 | Kino Lorber | false | false |
| 31 | - | First Date | $10,183 | - | 21 | - | $484 | $10,183 | 1 | Magnolia Pictures | true | false |
| 32 | - | Summer of 85 | $10,052 | - | 19 | - | $529 | $51,007 | 3 | Music Box Films | false | false |
| 33 | - | The Swimming Pool 2021 Re-release | $9,598 | - | 9 | - | $1,066 | $110,137 | 8 | Rialto Distribution | false | false |
| 34 | - | The Red Circle 2021 Re-release | $7,402 | - | 1 | - | $7,402 | $24,640 | 2 | Rialto Pictures | false | false |
| 35 | - | The Dry | $6,215 | - | 7 | - | $887 | $353,355 | 7 | IFC Films | false | false |
| 36 | - | Shiva Baby | $3,629 | - | 6 | - | $604 | $149,554 | - | Utopia | - | false |
| 37 | - | The Ladykillers 2021 Re-release | $3,226 | - | 3 | - | $1,075 | $15,998 | 5 | Rialto Pictures | false | false |
| 38 | - | Undine | $2,510 | - | 6 | - | $418 | $72,479 | 5 | IFC Films | false | false |
| 39 | - | Censor | $2,316 | - | 4 | - | $579 | $86,367 | 4 | Magnolia Pictures | false | false |
| 40 | - | Lydia Lunch: The War Is Never Over | $2,034 | - | 1 | - | $2,034 | $5,385 | 1 | Kino Lorber | true | false |
| 41 | - | Our Ladies | $1,703 | - | 12 | - | $141 | $26,709 | 3 | Sony Pictures Releasing | false | false |
| 42 | - | About Endlessness | $1,419 | - | 1 | - | $1,419 | $47,488 | 10 | Magnolia Pictures | false | false |
| 43 | - | Operation Portugal | $888 | - | 10 | - | $88 | $888 | 1 | Sony Pictures Releasing | true | false |
| 44 | - | Together Together | $476 | - | 4 | - | $119 | $1,436,146 | 11 | Bleecker Street Media | false | false |
| 45 | - | Holler | $338 | - | 4 | - | $84 | $28,394 | 4 | IFC Films | false | false |
| 46 | - | The Evil Next Door | $248 | - | 2 | - | $124 | $792 | 2 | Magnolia Pictures | false | false |
