| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | F9: The Fast Saga | $8,348,323 | - | 594 | - | $14,054 | $8,348,323 | 1 | Universal Pictures | true | false |
| 2 | 2 | Peter Rabbit 2: The Runaway | $1,154,888 | -25% | 608 | -3 | $1,899 | $22,699,520 | 6 | Sony Pictures Releasing | false | false |
| 3 | 3 | In the Heights | $956,470 | -35.5% | 632 | +2 | $1,513 | $3,311,155 | 2 | Warner Bros. | false | false |
| 4 | 4 | A Quiet Place Part II | $827,088 | -41.6% | 539 | -48 | $1,534 | $13,282,203 | 4 | Paramount Pictures | false | false |
| 5 | 5 | Cruella | $643,212 | -36.3% | 525 | -41 | $1,225 | $10,832,754 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 6 | 1 | Hitman's Wife's Bodyguard | $619,858 | -72.6% | 513 | -9 | $1,208 | $3,615,161 | 2 | Lionsgate | false | false |
| 7 | 6 | The Conjuring: The Devil Made Me Do It | $413,901 | -39.4% | 369 | -95 | $1,121 | $11,635,625 | 5 | Warner Bros. | false | false |
| 8 | - | Supernova | $341,081 | - | 353 | - | $966 | $341,081 | 1 | StudioCanal UK | true | false |
| 9 | - | Dogtanian and the Three Muskehounds | $294,745 | - | 479 | - | $615 | $294,745 | 1 | Altitude Film Entertainment | true | false |
| 10 | 7 | The Father | $186,700 | -60% | 426 | -191 | $438 | $2,217,468 | 3 | Lionsgate | false | false |
| 11 | 8 | Nobody | $78,354 | -71.8% | 202 | -250 | $387 | $1,674,692 | 3 | Universal Pictures | false | false |
| 12 | 12 | Tom & Jerry | $50,072 | -42.9% | 202 | -52 | $247 | $1,235,364 | 11 | Warner Bros. | false | false |
| 13 | 11 | Raya and the Last Dragon | $37,982 | -61.4% | 212 | -164 | $179 | $987,074 | 6 | Walt Disney Pictures | false | false |
| 14 | 10 | Godzilla vs. Kong | $33,424 | -68.2% | 118 | -112 | $283 | $3,608,866 | 11 | Warner Bros. | false | false |
| 15 | 9 | Monster Hunter | $29,509 | -85.8% | 174 | -96 | $169 | $326,252 | 2 | Sony Pictures Releasing | false | false |
| 16 | 13 | In the Earth | $25,137 | -68.9% | 73 | -101 | $344 | $179,352 | 2 | Universal Pictures | false | false |
| 17 | 15 | Dream Horse | $19,546 | -45.6% | 63 | -90 | $310 | $872,873 | 4 | Warner Bros. | false | false |
| 18 | - | Uncle Vanya | $15,189 | - | 88 | - | $172 | $231,792 | 36 | More2Screen | false | false |
| 19 | 17 | The Reason I Jump | $12,029 | -39.4% | 36 | -2 | $334 | $58,437 | 2 | Picturehouse Entertainment | false | false |
| 20 | - | Fatima | $9,119 | - | 36 | - | $253 | $9,119 | 1 | - | true | false |
| 21 | - | Hey Duggee at the Movies 2020 Re-release | $9,081 | - | 86 | - | $105 | $89,100 | - | Vue Entertainment | - | false |
| 22 | - | Nashville 2021 Re-release | $7,135 | - | 5 | - | $1,427 | $7,135 | 1 | British Film Institute (BFI) | true | false |
| 23 | - | Sweat 2021 Re-release | $6,462 | - | 19 | - | $340 | $6,462 | 1 | Curzon Film Distributors | true | false |
| 24 | 18 | After Love | $4,504 | -60.9% | 10 | -16 | $450 | $129,474 | 4 | British Film Institute (BFI) | false | false |
| 25 | 25 | The Witches | $3,406 | +90.1% | 30 | +8 | $113 | $33,903 | 11 | Warner Bros. | false | false |
| 26 | 20 | Room on the Broom | $3,266 | -20.1% | 17 | -1 | $192 | $63,738 | 48 | - | false | false |
| 27 | - | The Filmmaker's House | $2,646 | - | 9 | - | $294 | $2,646 | 1 | Verve Pictures | true | false |
| 28 | 27 | Rare Beasts | $1,241 | +117.7% | 3 | - | $413 | $59,774 | 6 | - | false | false |
| 29 | - | Sparkling: The Story of Champagne | $1,188 | - | 1 | - | $1,188 | $1,188 | 1 | Swipe Films | true | false |
| 30 | 22 | The Tale of the Fatherless | $600 | -79.2% | 2 | -2 | $300 | $5,219 | 2 | - | false | false |
| 31 | - | Mamma Mia! 2020 Re-release | $521 | - | 1 | - | $521 | $1,181,539 | 51 | Universal Pictures | false | false |
| 32 | - | 2001: A Space Odyssey 2020 Re-release | $383 | - | 1 | - | $383 | - | 52 | British Film Institute (BFI) | false | false |
| 33 | - | The Secret Garden | $382 | - | 2 | - | $191 | $1,027,210 | 36 | Altitude Film Entertainment | false | false |
| 34 | - | Matthew Bourne's Romeo and Juliet | $350 | - | 1 | - | $350 | $622,569 | 1 | Trafalgar Releasing | true | false |
| 35 | 23 | Six Minutes to Midnight | $341 | -85.9% | 2 | -3 | $170 | $49,024 | 14 | Lionsgate | false | false |
| 36 | - | The King & I: From the London Palladium | $328 | - | 1 | - | $328 | $2,657,054 | 136 | Trafalgar Releasing | false | false |
| 37 | 32 | Exhibition on Screen: Sunflowers | $300 | +261.4% | 1 | - | $300 | $12,919 | 4 | Seventh Art Productions | false | false |
| 38 | - | Undergods | $292 | - | 2 | - | $146 | $6,417 | 7 | Munro Films | false | false |
| 39 | 24 | Ammonite | $218 | -89.9% | 5 | +3 | $43 | $242,715 | 6 | Lionsgate | false | false |
| 40 | 29 | Akram Khan's Giselle | $215 | -49.4% | 1 | - | $215 | $167,039 | 2 | Trafalgar Releasing | false | false |
| 41 | - | 2020 Re-release | $174 | - | 1 | - | $174 | $139,180 | 34 | National Theatre | false | false |
| 42 | - | Granada Nights | $158 | - | 1 | - | $158 | $3,783 | 5 | - | false | false |
| 43 | - | A Space in Time | $104 | - | 1 | - | $104 | $104 | 1 | Bohemia MP | true | false |
