| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inside Out | $20,509 | -24.8% | 31 | - | $661 | $208,646 | 4 | N/A | false | false |
| 2 | - | Vacation | $16,386 | - | 10 | - | $1,638 | $16,386 | 1 | Warner Bros. | true | false |
| 3 | - | American Ultra | $10,949 | - | 11 | - | $995 | $11,020 | 1 | N/A | true | false |
| 4 | 3 | The Man from U.N.C.L.E. | $8,769 | -40.3% | 5 | -4 | $1,753 | $67,951 | 3 | Warner Bros. | false | false |
| 5 | 2 | Hitman: Agent 47 | $8,082 | -49.8% | 6 | -4 | $1,347 | $34,323 | 2 | N/A | false | false |
| 6 | 4 | Mission: Impossible - Rogue Nation | $7,867 | -20.9% | 3 | -1 | $2,622 | $152,534 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | - | Ricki and the Flash | $6,965 | - | 9 | - | $773 | $6,965 | 1 | Sony Pictures Releasing | true | false |
| 8 | 5 | Minions | $6,791 | -26.5% | 15 | +1 | $452 | $819,515 | 10 | Universal Pictures International (UPI) | false | false |
| 9 | - | Knock Knock | $6,097 | - | 6 | - | $1,016 | $6,136 | 1 | ACME | true | false |
| 10 | 7 | Southpaw | $2,965 | -58.3% | 6 | -1 | $494 | $34,223 | 3 | N/A | false | false |
| 11 | 6 | Sinister 2 | $2,960 | -59.2% | 3 | -4 | $986 | $35,794 | 3 | N/A | false | false |
| 12 | 8 | We Are Your Friends | $2,191 | -67.8% | 6 | -2 | $365 | $15,733 | 2 | ACME | false | false |
| 13 | 9 | Trainwreck | $1,358 | -64.7% | 2 | -3 | $679 | $33,399 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 16 | Magic Mike XXL | $843 | +3.4% | 1 | - | $843 | $62,065 | 7 | Warner Bros. | false | false |
| 15 | 12 | Self/less | $653 | -59.3% | 1 | -1 | $653 | $40,316 | 6 | Universal Pictures International (UPI) | false | false |
| 16 | 10 | Daddy or Mommy | $585 | -71.4% | 3 | -1 | $195 | $9,725 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | 13 | Pixels | $437 | -70.4% | 1 | -1 | $437 | $78,898 | 7 | Sony Pictures Releasing | false | false |
| 18 | 11 | Paper Towns | $388 | -77.9% | 1 | - | $388 | $41,368 | 7 | N/A | false | false |
| 19 | 19 | Some Kind of Beautiful | $241 | +14.8% | 1 | - | $241 | $6,301 | 5 | N/A | false | false |
| 20 | 14 | Fantastic Four | $102 | -92.8% | 1 | -3 | $102 | $23,251 | 4 | N/A | false | false |
