| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Captain America: The First Avenger | $48,655 | - | 23 | - | $2,115 | $73,134 | 1 | United International Pictures | true | false |
| 2 | - | Friends with Benefits | $30,824 | - | 19 | - | $1,622 | $30,824 | 1 | Sony Pictures Releasing | true | false |
| 3 | 1 | Harry Potter and the Deathly Hallows: Part 2 | $29,203 | -44.8% | 23 | -12 | $1,269 | $437,657 | 3 | Warner Bros. | false | false |
| 4 | 3 | Winnie the Pooh | $19,190 | -8.9% | 15 | -1 | $1,279 | $65,133 | 2 | Walt Disney Pictures | false | false |
| 5 | 2 | Transformers: Dark of the Moon | $13,255 | -47.4% | 21 | -5 | $631 | $724,505 | 5 | United International Pictures | false | false |
| 6 | 4 | Cars 2 | $11,728 | -22.7% | 21 | +1 | $558 | $422,356 | 6 | Walt Disney Pictures | false | false |
| 7 | 5 | Bad Teacher | $8,413 | -33.1% | 12 | -3 | $701 | $294,682 | 6 | Sony Pictures Releasing | false | false |
| 8 | 7 | Mr. Popper's Penguins | $4,808 | -22.9% | 10 | -2 | $480 | $105,093 | 5 | 20th Century Fox International | false | false |
| 9 | 6 | The Hangover Part II | $4,316 | -38.5% | 13 | - | $332 | $497,624 | 10 | Warner Bros. | false | false |
| 10 | 9 | Pirates of the Caribbean: On Stranger Tides | $3,755 | -17.4% | 7 | - | $536 | $1,503,655 | 11 | Walt Disney Pictures | false | false |
| 11 | 8 | Larry Crowne | $3,555 | -37.6% | 9 | - | $395 | $62,131 | 4 | N/A | false | false |
| 12 | 10 | Kung Fu Panda 2 | $2,795 | -28.8% | 8 | -2 | $349 | $527,551 | 9 | United International Pictures | false | false |
| 13 | 12 | Fast Five | $2,160 | -19.7% | 5 | -1 | $432 | $785,515 | 13 | United International Pictures | false | false |
| 14 | 11 | Super 8 | $1,619 | -49.5% | 9 | +1 | $179 | $148,018 | 7 | United International Pictures | false | false |
| 15 | 19 | Water for Elephants | $1,292 | +120.9% | 2 | -1 | $646 | $71,534 | 12 | 20th Century Fox International | false | false |
| 16 | 16 | Love.net | $1,196 | +32.6% | 5 | -1 | $239 | $1,006,778 | 18 | Alexandra Films | false | false |
| 17 | 13 | X-Men: First Class | $721 | -57.5% | 3 | -3 | $240 | $186,118 | 8 | 20th Century Fox International | false | false |
| 18 | 18 | The Tree of Life | $707 | +19.6% | 2 | -1 | $353 | $88,481 | 9 | N/A | false | false |
| 19 | 21 | Tangled | $23 | - | 3 | - | $7 | $926,718 | 35 | Walt Disney Pictures | false | false |
| 20 | 20 | Rango | $9 | -75% | 3 | - | $3 | $218,773 | 21 | United International Pictures | false | false |
