| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Deathly Hallows: Part 2 | $1,225,129 | - | 96 | - | $12,761 | $1,225,129 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Cars 2 | $412,462 | -59% | 88 | -8 | $4,687 | $1,844,276 | 2 | Ster-Kinekor Pictures | false | false |
| 3 | 2 | Transformers: Dark of the Moon | $280,772 | -48.1% | 68 | -17 | $4,129 | $2,908,233 | 3 | United International Pictures | false | false |
| 4 | 3 | Something Borrowed | $118,549 | -32.7% | 51 | - | $2,324 | $416,555 | 2 | NuMetro Distribution | false | false |
| 5 | 6 | Madea's Big Happy Family | $86,232 | -24.1% | 35 | -5 | $2,463 | $572,621 | 3 | Ster-Kinekor Pictures | false | false |
| 6 | 7 | Bridesmaids | $78,304 | -27.6% | 51 | -2 | $1,535 | $818,688 | 4 | United International Pictures | false | false |
| 7 | 5 | Kung Fu Panda 2 | $76,468 | -39.9% | 50 | -12 | $1,529 | $2,966,995 | 6 | United International Pictures | false | false |
| 8 | 8 | The Hangover Part II | $69,070 | -30.6% | 55 | -2 | $1,255 | $2,565,590 | 8 | NuMetro Distribution | false | false |
| 9 | 4 | Scream 4 | $62,424 | -60.5% | 55 | - | $1,134 | $289,464 | 2 | Ster-Kinekor Pictures | false | false |
| 10 | 10 | Mr. Popper's Penguins | $46,261 | -20.2% | 45 | -8 | $1,028 | $805,014 | 5 | NuMetro Distribution | false | false |
| 11 | 11 | Pirates of the Caribbean: On Stranger Tides | $30,385 | -37.1% | 22 | -4 | $1,381 | $3,515,146 | 9 | Ster-Kinekor Pictures | false | false |
| 12 | 9 | Green Lantern | $19,724 | -66.7% | 29 | -18 | $680 | $915,595 | 4 | NuMetro Distribution | false | false |
| 13 | 12 | X-Men: First Class | $15,133 | -44.1% | 21 | -4 | $720 | $1,151,613 | 7 | NuMetro Distribution | false | false |
| 14 | 15 | Jumping the Broom | $13,624 | -18.1% | 15 | -1 | $908 | $327,787 | 5 | Ster-Kinekor Pictures | false | false |
| 15 | 14 | All Good Things 2010 Re-release | $11,206 | -38.9% | 9 | -3 | $1,245 | $140,608 | 4 | Ster-Kinekor Pictures | false | false |
| 16 | 16 | The Lincoln Lawyer | $11,068 | -25.9% | 8 | -1 | $1,383 | $432,545 | 7 | NuMetro Distribution | false | false |
| 17 | - | Win Win | $9,345 | - | 6 | - | $1,557 | $29,347 | 2 | N/A | false | false |
| 18 | 19 | Fast Five | $6,049 | -14.2% | 9 | -1 | $672 | $2,638,763 | 11 | United International Pictures | false | false |
| 19 | - | Roepman | $5,696 | - | 9 | - | $632 | $328,350 | 9 | Ster-Kinekor Pictures | false | false |
| 20 | 21 | The Adjustment Bureau | $3,548 | -20% | 6 | - | $591 | $347,969 | 6 | United International Pictures | false | false |
| 21 | 20 | Hanna | $3,510 | -43% | 5 | -1 | $702 | $142,528 | 8 | Ster-Kinekor Pictures | false | false |
| 22 | 22 | My Hunter's Heart | $1,264 | +6.6% | 2 | - | $632 | $3,127 | 2 | United International Pictures | false | false |
