| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rio | $362,455 | -45% | 94 | - | $3,855 | $1,128,003 | 2 | NuMetro Distribution | false | false |
| 2 | - | Limitless | $157,894 | - | 50 | - | $3,157 | $157,894 | 1 | NuMetro Distribution | true | false |
| 3 | 3 | Just Go with It | $127,523 | -28.5% | 63 | -1 | $2,024 | $1,710,644 | 5 | Ster-Kinekor Pictures | false | false |
| 4 | 2 | Unknown | $119,491 | -34.6% | 50 | - | $2,389 | $372,391 | 2 | NuMetro Distribution | false | false |
| 5 | - | Water for Elephants | $100,910 | - | 40 | - | $2,522 | $100,910 | 1 | NuMetro Distribution | true | false |
| 6 | 4 | No Strings Attached | $100,798 | -31.7% | 55 | - | $1,832 | $630,739 | 3 | United International Pictures | false | false |
| 7 | 5 | Hop | $80,772 | -34.7% | 76 | -1 | $1,062 | $587,570 | 3 | United International Pictures | false | false |
| 8 | 7 | The Mechanic | $57,843 | -44.1% | 48 | - | $1,205 | $435,819 | 3 | N/A | false | false |
| 9 | 6 | Rango | $52,967 | -51.9% | 61 | -8 | $868 | $1,336,750 | 5 | United International Pictures | false | false |
| 10 | 8 | Gnomeo & Juliet | $47,110 | -42.5% | 27 | -22 | $1,744 | $1,137,422 | 4 | Ster-Kinekor Pictures | false | false |
| 11 | 10 | The Eagle | $28,387 | -56.8% | 40 | - | $709 | $120,265 | 2 | Ster-Kinekor Pictures | false | false |
| 12 | - | The Roommate | $24,140 | - | 15 | - | $1,609 | $24,140 | 1 | Ster-Kinekor Pictures | true | false |
| 13 | 11 | Big Mommas: Like Father, Like Son | $22,814 | -41.3% | 25 | -6 | $912 | $1,298,413 | 8 | NuMetro Distribution | false | false |
| 14 | 9 | I Am Number Four | $22,397 | -67% | 29 | -22 | $772 | $636,087 | 4 | Ster-Kinekor Pictures | false | false |
| 15 | 14 | The King's Speech | $20,525 | -22.3% | 14 | -1 | $1,466 | $1,297,446 | 10 | Ster-Kinekor Pictures | false | false |
| 16 | - | Tomorrow, When the War Began | $20,504 | - | 37 | - | $554 | $20,504 | 1 | United International Pictures | true | false |
| 17 | 12 | Hall Pass | $14,584 | -59.2% | 22 | -10 | $662 | $424,450 | 4 | NuMetro Distribution | false | false |
| 18 | 15 | Paradise Stop | $10,718 | -50.7% | 11 | -4 | $974 | $246,625 | 4 | N/A | false | false |
| 19 | 16 | Barney's Version | $9,695 | -27% | 7 | - | $1,385 | $27,023 | 2 | NuMetro Distribution | false | false |
| 20 | 18 | Somewhere | $4,613 | -33.4% | 6 | - | $768 | $16,311 | 2 | Ster-Kinekor Pictures | false | false |
| 21 | - | Miral | $3,157 | - | 4 | - | $789 | $3,157 | 1 | Ster-Kinekor Pictures | true | false |
| 22 | 19 | True Grit | $2,512 | -52.4% | 4 | -3 | $628 | $184,600 | 9 | United International Pictures | false | false |
| 23 | 20 | Justin Bieber: Never Say Never | $666 | -79.7% | 1 | - | $666 | $250,849 | 6 | United International Pictures | false | false |
| 24 | 21 | The Dilemma | $527 | -70.1% | 2 | -3 | $263 | $324,295 | 7 | NuMetro Distribution | false | false |
| 25 | 25 | Of Gods and Men | $279 | +28.6% | 1 | - | $279 | $26,239 | 8 | United International Pictures | false | false |
