| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Big Mommas: Like Father, Like Son | $195,360 | -29.2% | 61 | -1 | $3,202 | $551,188 | 2 | NuMetro Distribution | false | false |
| 2 | 2 | Tangled | $164,557 | -24.8% | 51 | -25 | $3,226 | $2,527,576 | 6 | Ster-Kinekor Pictures | false | false |
| 3 | 3 | The King's Speech | $119,471 | +16.9% | 24 | -1 | $4,977 | $693,677 | 4 | Ster-Kinekor Pictures | false | false |
| 4 | - | The Dilemma | $85,867 | - | 42 | - | $2,044 | $85,867 | 1 | NuMetro Distribution | true | false |
| 5 | 4 | How Do You Know | $64,109 | -24.4% | 44 | - | $1,457 | $377,176 | 3 | Ster-Kinekor Pictures | false | false |
| 6 | 9 | Black Swan | $54,987 | -2% | 25 | - | $2,199 | $553,871 | 5 | NuMetro Distribution | false | false |
| 7 | 5 | Saw 3D | $47,971 | -22.2% | 28 | - | $1,713 | $232,947 | 3 | Ster-Kinekor Pictures | false | false |
| 8 | 7 | The Tourist | $42,001 | -26.5% | 51 | -8 | $823 | $2,154,589 | 9 | Ster-Kinekor Pictures | false | false |
| 9 | 6 | The Fighter | $40,703 | -28.9% | 39 | -1 | $1,043 | $133,758 | 2 | Ster-Kinekor Pictures | false | false |
| 10 | 8 | The Green Hornet | $35,946 | -36.9% | 42 | -12 | $855 | $698,249 | 5 | Ster-Kinekor Pictures | false | false |
| 11 | 10 | Morning Glory | $31,844 | -40.2% | 46 | -14 | $692 | $398,673 | 4 | United International Pictures | false | false |
| 12 | 11 | Love & Other Drugs | $28,205 | -14.1% | 35 | - | $805 | $555,847 | 6 | NuMetro Distribution | false | false |
| 13 | - | Conviction 2010 Re-release | $18,275 | - | 16 | - | $1,142 | $18,275 | 1 | United International Pictures | true | false |
| 14 | 13 | True Grit | $17,586 | -25.5% | 12 | - | $1,465 | $102,333 | 3 | United International Pictures | false | false |
| 15 | 12 | The Next Three Days | $17,099 | -38.3% | 36 | -8 | $474 | $624,343 | 7 | NuMetro Distribution | false | false |
| 16 | 14 | 127 Hours | $16,137 | -29.1% | 18 | - | $896 | $100,102 | 3 | NuMetro Distribution | false | false |
| 17 | 15 | Gulliver's Travels | $11,283 | -35% | 21 | -5 | $537 | $986,058 | 9 | NuMetro Distribution | false | false |
| 18 | 16 | Burlesque | $9,358 | -29.4% | 16 | -4 | $584 | $577,110 | 7 | Ster-Kinekor Pictures | false | false |
| 19 | 21 | Fair Game | $8,153 | +39.2% | 21 | +7 | $388 | $156,254 | 5 | NuMetro Distribution | false | false |
| 20 | - | Night Drive | $7,410 | - | 10 | - | $741 | $7,410 | 1 | Indigenous Film Distribution | true | false |
| 21 | 18 | Of Gods and Men | $4,869 | -34.1% | 7 | -1 | $695 | $16,347 | 2 | United International Pictures | false | false |
| 22 | 20 | The Concert | $3,934 | -38.9% | 4 | -2 | $983 | $216,853 | 9 | United International Pictures | false | false |
| 23 | 19 | Little Fockers | $3,494 | -51.2% | 9 | -3 | $388 | $1,991,074 | 11 | United International Pictures | false | false |
| 24 | 22 | Made in Dagenham | $1,451 | -37.4% | 2 | -1 | $725 | $116,026 | 7 | United International Pictures | false | false |
| 25 | 23 | Splice 2010 Re-release | $400 | -63.3% | 2 | -2 | $200 | $71,812 | 6 | United International Pictures | false | false |
