| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Tangled | $8,099,434 | - | 445 | - | $18,200 | $8,099,434 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | The King's Speech | $5,764,191 | -14.8% | 536 | +34 | $10,754 | $39,501,623 | 4 | Momentum Pictures | false | false |
| 3 | 2 | Black Swan | $4,070,399 | -7.9% | 429 | +73 | $9,488 | $11,587,272 | 2 | 20th Century Fox International | false | false |
| 4 | - | The Mechanic | $1,461,647 | - | 301 | - | $4,855 | $1,461,647 | 1 | Lionsgate | true | false |
| 5 | 4 | The Dilemma | $1,061,663 | -39.9% | 415 | -4 | $2,558 | $3,635,285 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 3 | The Green Hornet | $1,040,139 | -45.3% | 352 | -79 | $2,954 | $7,780,295 | 3 | Sony Pictures Releasing | false | false |
| 7 | - | Hereafter | $954,382 | - | 274 | - | $3,483 | $954,382 | 1 | Warner Bros. | true | false |
| 8 | 5 | Gulliver's Travels | $928,246 | -41.6% | 432 | -51 | $2,148 | $23,001,759 | 6 | 20th Century Fox International | false | false |
| 9 | 6 | 127 Hours | $649,278 | -49.6% | 293 | -53 | $2,215 | $10,476,342 | 4 | Warner Bros. | false | false |
| 10 | - | How Do You Know | $594,669 | - | 211 | - | $2,818 | $594,669 | 1 | Sony Pictures Releasing | true | false |
| 11 | 7 | Little Fockers | $493,526 | -55% | 281 | -109 | $1,756 | $29,810,064 | 6 | Paramount Pictures International | false | false |
| 12 | 10 | Neds | $298,404 | -34.2% | 67 | -5 | $4,453 | $1,002,719 | 2 | Entertainment One | false | false |
| 13 | 8 | Morning Glory | $290,926 | -65.3% | 303 | +29 | $960 | $1,652,085 | 2 | Paramount Pictures International | false | false |
| 14 | 9 | Harry Potter and the Deathly Hallows: Part 1 | $252,372 | -54.5% | 216 | -70 | $1,168 | $82,857,014 | 11 | Warner Bros. | false | false |
| 15 | - | Biutiful | $247,473 | - | 47 | - | $5,265 | $247,473 | 1 | Optimum Releasing | true | false |
| 16 | - | Barney's Version | $173,303 | - | 141 | - | $1,229 | $173,303 | 1 | Universal Pictures International (UPI) | true | false |
| 17 | 12 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $137,336 | -64.7% | 232 | -101 | $591 | $22,304,371 | 8 | 20th Century Fox International | false | false |
| 18 | 15 | TRON: Legacy | $121,781 | -52.5% | 116 | +3 | $1,049 | $16,221,225 | 7 | Walt Disney Pictures | false | false |
| 19 | 14 | Megamind | $116,777 | -62.7% | 219 | -79 | $533 | $15,869,551 | 9 | Paramount Pictures International | false | false |
| 20 | 11 | Love & Other Drugs | $110,449 | -72.8% | 102 | -161 | $1,082 | $8,686,760 | 5 | 20th Century Fox International | false | false |
| 21 | - | Dil Toh Baccha Hai Ji | $33,016 | - | 13 | - | $2,539 | $33,016 | 1 | N/A | true | false |
| 22 | - | Men on the Bridge | $3,121 | - | 1 | - | $3,121 | $2,693 | 1 | Verve Pictures | true | false |
| 23 | 19 | Another Year | $3,006 | -44.3% | 3 | -1 | $1,002 | $2,688,739 | 13 | Momentum Pictures | false | false |
| 24 | 20 | Charlie Noades R.I.P | $2,657 | -4.5% | 3 | - | $885 | $7,846 | 2 | Guerilla Films | false | false |
| 25 | - | The Lovers' Guide: Igniting Desire | $416 | - | 1 | - | $416 | $416 | 1 | Optimum Releasing | true | false |
| 26 | 26 | The Arbor | $308 | +862.5% | 1 | - | $308 | $102,378 | 15 | Verve Pictures | false | false |
