| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Megamind | $646,411 | - | 74 | - | $8,735 | $646,411 | 1 | United International Pictures | true | false |
| 2 | - | Due Date | $369,751 | - | 61 | - | $6,061 | $369,751 | 1 | NuMetro Distribution | true | false |
| 3 | 1 | The Chronicles of Narnia: The Voyage of the Dawn Treader | $220,147 | -45.9% | 108 | -5 | $2,038 | $1,018,191 | 2 | NuMetro Distribution | false | false |
| 4 | 2 | Spud | $170,364 | -35.5% | 84 | +2 | $2,028 | $1,437,304 | 3 | NuMetro Distribution | false | false |
| 5 | 3 | Harry Potter and the Deathly Hallows: Part 1 | $99,238 | -30.9% | 81 | -7 | $1,225 | $1,932,442 | 4 | NuMetro Distribution | false | false |
| 6 | 4 | Liefling | $85,332 | -30.6% | 59 | -12 | $1,446 | $1,521,817 | 5 | Indigenous Film Distribution | false | false |
| 7 | 5 | Faster | $49,796 | -17.9% | 34 | -4 | $1,464 | $322,268 | 3 | Ster-Kinekor Pictures | false | false |
| 8 | 9 | Red | $39,800 | -11.7% | 26 | -9 | $1,530 | $655,546 | 5 | NuMetro Distribution | false | false |
| 9 | 6 | Stoute Boudjies | $35,650 | -29.3% | 35 | -5 | $1,018 | $125,507 | 2 | Ster-Kinekor Pictures | false | false |
| 10 | 8 | Paranormal Activity 2 | $33,802 | -27.2% | 15 | - | $2,253 | $125,967 | 2 | United International Pictures | false | false |
| 11 | 10 | Unstoppable | $30,137 | -1.6% | 30 | - | $1,004 | $821,840 | 6 | NuMetro Distribution | false | false |
| 12 | 7 | The American | $25,546 | -46.9% | 24 | -14 | $1,064 | $237,194 | 3 | Ster-Kinekor Pictures | false | false |
| 13 | 12 | Life as We Know It | $19,949 | -13.2% | 19 | -5 | $1,049 | $1,172,038 | 8 | NuMetro Distribution | false | false |
| 14 | 15 | Scott Pilgrim vs. the World | $8,681 | -33% | 9 | -5 | $964 | $72,639 | 3 | United International Pictures | false | false |
| 15 | 16 | You Again | $8,080 | -27.5% | 6 | -1 | $1,346 | $349,186 | 7 | Ster-Kinekor Pictures | false | false |
| 16 | 17 | Takers 2010 Re-release | $6,447 | -0.1% | 9 | -3 | $716 | $440,190 | 8 | Ster-Kinekor Pictures | false | false |
| 17 | 14 | Despicable Me | $5,652 | -71.3% | 5 | -15 | $1,130 | $2,285,581 | 12 | United International Pictures | false | false |
| 18 | 13 | Jackass 3D | $4,479 | -78.3% | 3 | -15 | $1,493 | $490,511 | 5 | United International Pictures | false | false |
| 19 | 20 | The Social Network | $3,509 | +24.9% | 3 | - | $1,169 | $360,226 | 7 | Ster-Kinekor Pictures | false | false |
| 20 | 18 | Coco Chanel & Igor Stravinsky | $2,204 | -39.3% | 3 | -1 | $734 | $33,132 | 4 | United International Pictures | false | false |
| 21 | 19 | Eat Pray Love | $1,977 | -44% | 4 | -3 | $494 | $1,783,407 | 11 | Sony Pictures Releasing | false | false |
| 22 | 23 | The Karate Kid | $1,238 | +27% | 1 | -1 | $1,238 | $1,829,441 | 14 | Sony Pictures Releasing | false | false |
| 23 | 22 | The Kids Are All Right | $995 | - | 1 | -1 | $995 | $35,900 | 6 | United International Pictures | false | false |
| 24 | 21 | Eyes Wide Open | $994 | -9.6% | 1 | - | $994 | $24,376 | 6 | United International Pictures | false | false |
