| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Spud | $423,433 | - | 83 | - | $5,101 | $423,433 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Harry Potter and the Deathly Hallows: Part 1 | $289,587 | -62.4% | 111 | -1 | $2,608 | $1,384,572 | 2 | NuMetro Distribution | false | false |
| 3 | 2 | Liefling | $173,971 | -30.6% | 78 | -19 | $2,230 | $1,033,213 | 3 | Indigenous Film Distribution | false | false |
| 4 | - | Faster | $88,067 | - | 41 | - | $2,147 | $88,067 | 1 | Ster-Kinekor Pictures | true | false |
| 5 | - | The American | $73,023 | - | 40 | - | $1,825 | $73,023 | 1 | Ster-Kinekor Pictures | true | false |
| 6 | 4 | RED | $69,977 | -35.1% | 42 | -3 | $1,666 | $478,243 | 3 | NuMetro Distribution | false | false |
| 7 | 3 | Unstoppable | $59,703 | -47.1% | 51 | -10 | $1,170 | $682,534 | 4 | NuMetro Distribution | false | false |
| 8 | 5 | Life as We Know It | $54,048 | -44.5% | 46 | -13 | $1,174 | $1,063,314 | 6 | NuMetro Distribution | false | false |
| 9 | 6 | Jackass 3D | $52,834 | -45% | 31 | -3 | $1,704 | $392,908 | 3 | United International Pictures | false | false |
| 10 | 7 | Despicable Me | $31,247 | -41.5% | 23 | -17 | $1,358 | $2,205,734 | 10 | United International Pictures | false | false |
| 11 | 8 | You Again | $19,839 | -44.3% | 13 | -12 | $1,526 | $301,037 | 5 | Ster-Kinekor Pictures | false | false |
| 12 | - | Scott Pilgrim vs. the World | $19,506 | - | 15 | - | $1,300 | $19,506 | 1 | United International Pictures | true | false |
| 13 | 9 | Takers 2010 Re-release | $12,932 | -46.9% | 18 | -6 | $718 | $411,629 | 6 | Ster-Kinekor Pictures | false | false |
| 14 | 13 | Break Ke Baad | $12,116 | -19.3% | 6 | - | $2,019 | $35,021 | 2 | NuMetro Distribution | false | false |
| 15 | 14 | The Girl Who Played with Fire | $10,501 | -19.1% | 9 | -1 | $1,166 | $148,095 | 5 | NuMetro Distribution | false | false |
| 16 | 16 | The Girl with the Dragon Tattoo | $9,801 | -8.8% | 8 | -3 | $1,225 | $276,717 | 8 | NuMetro Distribution | false | false |
| 17 | 10 | Eat Pray Love | $7,474 | -67.5% | 11 | -18 | $679 | $1,777,771 | 9 | Sony Pictures Releasing | false | false |
| 18 | 11 | The Social Network | $7,197 | -66.9% | 7 | -10 | $1,028 | $347,562 | 5 | Ster-Kinekor Pictures | false | false |
| 19 | 19 | Coco Chanel & Igor Stravinsky | $5,806 | -31% | 6 | - | $967 | $20,167 | 2 | United International Pictures | false | false |
| 20 | 21 | The Kids Are All Right | $3,546 | -22.1% | 3 | - | $1,182 | $27,668 | 4 | United International Pictures | false | false |
| 21 | 15 | The Other Guys | $2,367 | -80.5% | 4 | -13 | $591 | $1,204,080 | 11 | Sony Pictures Releasing | false | false |
| 22 | 24 | Eyes Wide Open | $1,942 | -28% | 2 | - | $971 | $20,168 | 4 | United International Pictures | false | false |
| 23 | 22 | Why Did I Get Married Too? | $1,749 | -58.9% | 6 | -3 | $291 | $558,754 | 10 | Ster-Kinekor Pictures | false | false |
| 24 | 18 | The Crazies | $1,646 | -81.5% | 6 | -9 | $274 | $75,533 | 4 | United International Pictures | false | false |
| 25 | 20 | Charlie St. Cloud | $829 | -86.6% | 2 | -14 | $414 | $291,268 | 7 | United International Pictures | false | false |
