| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Deathly Hallows: Part 1 | $100,959 | - | 9 | - | $11,217 | $108,375 | 1 | Warner Bros. | true | false |
| 2 | - | Piranha 3D | $24,522 | - | 7 | - | $3,503 | $24,522 | 1 | ACME | true | false |
| 3 | 1 | Due Date | $22,487 | -13.2% | 8 | +1 | $2,810 | $124,000 | 3 | - | false | false |
| 4 | 2 | Despicable Me | $17,445 | -31.3% | 13 | -3 | $1,341 | $451,790 | 6 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | Unstoppable | $11,898 | -42.7% | 8 | - | $1,487 | $40,713 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | You Again | $8,737 | -25.4% | 6 | - | $1,456 | $25,651 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Saw 3D | $6,356 | -47.6% | 5 | -1 | $1,271 | $141,021 | 4 | ACME | false | false |
| 8 | 7 | Eat Pray Love | $5,361 | +35% | 5 | -1 | $1,072 | $226,665 | 7 | ACME | false | false |
| 9 | 8 | 13 | $4,616 | +41% | 2 | -1 | $2,308 | $21,388 | 3 | ACME | false | false |
| 10 | - | Agora | $3,976 | - | 2 | - | $1,988 | $3,976 | 1 | ACME | true | false |
| 11 | 6 | Easy A | $3,753 | -51.2% | 5 | - | $750 | $14,065 | 2 | ACME | false | false |
| 12 | 12 | Legend of the Guardians: The Owls of Ga'Hoole | $1,324 | -18.7% | 3 | - | $441 | $136,729 | 8 | - | false | false |
| 13 | - | Coco Chanel & Igor Stravinsky | $939 | - | 1 | - | $939 | $939 | 1 | Filmarti | true | false |
| 14 | 10 | The Switch | $899 | -66.3% | 2 | -2 | $449 | $38,222 | 4 | ACME | false | false |
| 15 | 13 | A Turtle's Tale: Sammy's Adventures | $662 | -44.6% | 2 | -2 | $331 | $99,585 | 10 | ACME | false | false |
| 16 | 16 | Devil | $537 | -14.6% | 2 | - | $268 | $27,147 | 5 | Universal Pictures International (UPI) | false | false |
| 17 | - | The Last Airbender | $338 | - | 1 | - | $338 | $156,021 | 14 | Universal Pictures International (UPI) | false | false |
| 18 | - | All That I Love | $218 | - | 1 | - | $218 | $3,252 | 9 | - | false | false |
| 19 | 22 | Buried | $191 | -24.8% | 1 | - | $191 | $89,520 | 8 | Incognito Films | false | false |
| 20 | - | 8 Dates 2010 Re-release | $157 | - | 1 | - | $157 | $7,021 | 9 | Filmarti | false | false |
| 21 | 19 | Of Love and Other Demons | $116 | -77.3% | 2 | - | $58 | $19,176 | 9 | Incognito Films | false | false |
