| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Deathly Hallows: Part 1 | $1,128,986 | - | 239 | - | $4,723 | $1,396,271 | 1 | Warner Bros. | true | false |
| 2 | 1 | Saw 3D | $227,952 | -51.1% | 73 | -32 | $3,122 | $1,854,874 | 3 | Cineplex | false | false |
| 3 | 2 | Paranormal Activity 2 | $101,873 | -44.3% | 68 | -5 | $1,498 | $1,397,456 | 4 | United International Pictures | false | false |
| 4 | 3 | Due Date | $77,271 | -39.4% | 52 | -18 | $1,485 | $499,541 | 3 | Warner Bros. | false | false |
| 5 | 4 | Devil | $54,800 | -39.6% | 40 | -4 | $1,370 | $200,616 | 2 | United International Pictures | false | false |
| 6 | 5 | The Other Guys | $38,439 | -51.2% | 39 | -1 | $985 | $159,556 | 2 | Sony Pictures Releasing | false | false |
| 7 | 6 | Life as We Know It | $35,864 | -47.2% | 26 | -17 | $1,379 | $472,161 | 4 | Warner Bros. | false | false |
| 8 | 8 | Eat Pray Love | $21,746 | -43.5% | 22 | -2 | $988 | $903,540 | 8 | Sony Pictures Releasing | false | false |
| 9 | 7 | Buried | $18,887 | -67.1% | 37 | -1 | $510 | $107,805 | 2 | Walt Disney Pictures | false | false |
| 10 | 10 | Tinker Bell and the Great Fairy Rescue | $11,996 | -42.9% | 23 | -13 | $521 | $470,449 | 7 | Walt Disney Pictures | false | false |
| 11 | 9 | Legend of the Guardians: The Owls of Ga'Hoole | $10,484 | -52.1% | 30 | -17 | $349 | $2,364,998 | 8 | Warner Bros. | false | false |
| 12 | 12 | Rage | $3,867 | -77% | 9 | -14 | $429 | $82,231 | 3 | Cine Colombia | false | false |
| 13 | 14 | A Single Man | $2,813 | -47.8% | 5 | -1 | $562 | $49,035 | 4 | - | false | false |
| 14 | - | Despicable Me | $1,108 | - | 5 | - | $221 | $2,751,755 | - | Universal Pictures International (UPI) | - | false |
| 15 | 17 | Grown Ups | $1,080 | -26.3% | 1 | - | $1,080 | $998,569 | 16 | Sony Pictures Releasing | false | false |
| 16 | 15 | The Town | $1,055 | -66.8% | 2 | -7 | $527 | $431,256 | 6 | Warner Bros. | false | false |
| 17 | 16 | Cats & Dogs: The Revenge of Kitty Galore | $956 | -56.6% | 6 | -3 | $159 | $2,094,843 | 15 | Warner Bros. | false | false |
| 18 | 11 | Piranha 3D | $857 | -95.8% | 4 | -18 | $214 | $716,661 | 5 | Cineplex | false | false |
| 19 | 13 | The Collector | $851 | -94.2% | 4 | -21 | $212 | $291,922 | 6 | Venus | false | false |
