| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Megamind | $388,522 | -22.2% | 75 | - | $5,180 | $976,701 | 2 | United International Pictures | false | false |
| 2 | - | Unstoppable | $262,679 | - | 55 | - | $4,775 | $262,679 | 1 | 20th Century Fox International | true | false |
| 3 | - | Easy A | $127,237 | - | 50 | - | $2,544 | $127,237 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Till My Heartaches End | $103,902 | -61.6% | 65 | -10 | $1,598 | $1,332,042 | 3 | Star Cinema | false | false |
| 5 | 3 | Due Date | $81,609 | -35.1% | 30 | - | $2,720 | $248,158 | 2 | Warner Bros. | false | false |
| 6 | - | Let Me In | $56,504 | - | 17 | - | $3,323 | $56,504 | 1 | Pioneer Films | true | false |
| 7 | 4 | Paranormal Activity 2 | $46,645 | -59% | 17 | - | $2,743 | $412,751 | 3 | United International Pictures | false | false |
| 8 | 7 | The Extraordinary Adventures of Adèle Blanc-Sec | $22,952 | -62.5% | 15 | -2 | $1,530 | $96,360 | 2 | Pioneer Films | false | false |
| 9 | 9 | The Town | $20,892 | -54.3% | 20 | -2 | $1,044 | $392,826 | 6 | Warner Bros. | false | false |
| 10 | 8 | The Social Network | $17,188 | -71.8% | 15 | -11 | $1,145 | $372,923 | 3 | Sony Pictures Releasing | false | false |
| 11 | 6 | Petrang kabayo | $17,045 | -79.6% | 30 | -20 | $568 | $2,638,400 | 5 | N/A | false | false |
| 12 | 12 | Life as We Know It | $13,247 | -57.2% | 22 | - | $602 | $427,060 | 4 | Warner Bros. | false | false |
| 13 | 5 | You Again | $10,498 | -90.3% | 21 | -29 | $499 | $138,868 | 2 | Walt Disney Pictures | false | false |
| 14 | 13 | Buried | $9,339 | -45.9% | 15 | -5 | $622 | $117,911 | 3 | Viva International Pictures | false | false |
| 15 | 15 | Legend of the Guardians: The Owls of Ga'Hoole | $6,575 | -33.8% | 2 | -1 | $3,287 | $1,478,692 | 8 | Warner Bros. | false | false |
| 16 | 10 | White House | $4,670 | -89.4% | 20 | -28 | $233 | $525,345 | 4 | N/A | false | false |
| 17 | 18 | Eat Pray Love | $3,463 | +58.3% | 2 | -1 | $1,731 | $554,960 | 6 | Sony Pictures Releasing | false | false |
| 18 | 21 | Charlie St. Cloud | $2,909 | +1,159.3% | 4 | +2 | $727 | $179,574 | 7 | United International Pictures | false | false |
| 19 | 17 | Wall Street: Money Never Sleeps | $423 | -81.5% | 1 | - | $423 | $439,806 | 7 | 20th Century Fox International | false | false |
| 20 | 19 | The Other Guys | $259 | -80.5% | 1 | - | $259 | $267,277 | 5 | Sony Pictures Releasing | false | false |
