| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Due Date | $467,026 | - | 62 | - | $7,532 | $1,124,767 | 2 | Warner Bros. | false | false |
| 2 | - | Unstoppable | $235,585 | - | 57 | - | $4,133 | $250,544 | 1 | 20th Century Fox International | true | false |
| 3 | - | RED | $215,074 | - | 44 | - | $4,888 | $1,209,948 | 3 | Ascot Elite Entertainment Group | false | false |
| 4 | - | The Switch | $155,782 | - | 28 | - | $5,563 | $360,595 | 1 | Ascot Elite Entertainment Group | true | false |
| 5 | - | Despicable Me | $143,150 | - | 43 | - | $3,329 | $4,818,593 | 7 | Universal Pictures International (UPI) | false | false |
| 6 | - | Jackass 3D | $124,766 | - | 21 | - | $5,941 | $637,490 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | - | Paranormal Activity 2 | $86,857 | - | 16 | - | $5,428 | $450,034 | 2 | Universal Pictures International (UPI) | false | false |
| 8 | - | Little White Lies | $76,029 | - | 15 | - | $5,068 | $688,360 | 4 | N/A | false | false |
| 9 | - | Buried | $75,699 | - | 32 | - | $2,365 | $254,718 | 2 | Ascot Elite Entertainment Group | false | false |
| 10 | - | The Social Network | $68,673 | - | 18 | - | $3,815 | $1,940,719 | 6 | Sony Pictures Releasing | false | false |
| 11 | - | The Kids Are All Right | $67,682 | - | 12 | - | $5,640 | $319,612 | 2 | N/A | false | false |
| 12 | - | Wall Street: Money Never Sleeps | $44,834 | - | 17 | - | $2,637 | $1,609,424 | 7 | 20th Century Fox International | false | false |
| 13 | - | Life as We Know It | $44,742 | - | 16 | - | $2,796 | $589,966 | 4 | Warner Bros. | false | false |
| 14 | - | Somewhere | $44,045 | - | 5 | - | $8,809 | $45,808 | 1 | N/A | true | false |
| 15 | - | Eat Pray Love | $38,179 | - | 22 | - | $1,735 | $2,939,580 | 8 | Sony Pictures Releasing | false | false |
| 16 | - | The American | $20,684 | - | 11 | - | $1,880 | $1,137,318 | 3 | Ascot Elite Entertainment Group | false | false |
| 17 | - | Legend of the Guardians: The Owls of Ga'Hoole | $20,564 | - | 9 | - | $2,284 | $606,254 | 3 | Warner Bros. | false | false |
