| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Elite Squad 2: The Enemy Within | $2,760,904 | -36.7% | 650 | -16 | $4,247 | $48,035,055 | 5 | N/A | false | false |
| 2 | - | Saw 3D | $1,455,363 | - | 267 | - | $5,450 | $1,457,929 | 1 | N/A | true | false |
| 3 | - | Due Date | $999,280 | - | 187 | - | $5,343 | $999,280 | 1 | Warner Bros. | true | false |
| 4 | 2 | Paranormal Activity 2 | $444,516 | -43% | 163 | -2 | $2,727 | $3,328,399 | 3 | Paramount Pictures International | false | false |
| 5 | 4 | Eat Pray Love | $351,618 | -39.5% | 201 | -24 | $1,749 | $9,860,468 | 6 | Sony Pictures Releasing | false | false |
| 6 | 3 | Garfield's Pet Force | $283,558 | -53.5% | 178 | -14 | $1,593 | $1,812,166 | 2 | PlayArte Pictures | false | false |
| 7 | 5 | Extreme Happiness | $194,507 | -52.6% | 164 | -4 | $1,186 | $1,015,355 | 2 | Paramount Pictures International | false | false |
| 8 | 6 | Life as We Know It | $194,251 | -44.6% | 111 | -30 | $1,750 | $2,190,984 | 4 | Warner Bros. | false | false |
| 9 | 7 | Grown Ups | $188,309 | -36.9% | 144 | -15 | $1,307 | $7,389,906 | 7 | Sony Pictures Releasing | false | false |
| 10 | 8 | The Town | $140,844 | -49.2% | 51 | - | $2,761 | $678,416 | 2 | Warner Bros. | false | false |
| 11 | 9 | Legend of the Guardians: The Owls of Ga'Hoole | $86,224 | -67% | 79 | -54 | $1,091 | $7,153,954 | 5 | Warner Bros. | false | false |
| 12 | 10 | Federal | $76,069 | -55.1% | 64 | +1 | $1,188 | $455,244 | 2 | Europa Filmes | false | false |
| 13 | 13 | Astral City: A Spiritual Journey | $41,612 | -37.7% | 77 | -32 | $540 | $21,122,941 | 10 | 20th Century Fox International | false | false |
| 14 | - | Scott Pilgrim vs. the World | $41,573 | - | 6 | - | $6,928 | $41,573 | 1 | United International Pictures | true | false |
| 15 | 18 | Vampires Suck | $34,817 | +11.7% | 65 | +1 | $535 | $2,206,808 | 6 | 20th Century Fox International | false | false |
| 16 | 12 | The Extraordinary Adventures of Adèle Blanc-Sec | $32,439 | -60.4% | 30 | -7 | $1,081 | $218,867 | 2 | N/A | false | false |
| 17 | 14 | Solitary Man | $24,375 | -62.6% | 17 | -9 | $1,433 | $324,146 | 3 | N/A | false | false |
| 18 | - | Cyrus | $21,252 | - | 7 | - | $3,036 | $24,104 | 1 | 20th Century Fox International | true | false |
| 19 | - | Ondine | $19,296 | - | 18 | - | $1,072 | $20,399 | 1 | N/A | true | false |
| 20 | 20 | Nanny McPhee Returns | $15,992 | -17.6% | 38 | -3 | $420 | $843,454 | 8 | Universal Pictures International (UPI) | false | false |
| 21 | 17 | The Switch | $15,732 | -57.5% | 19 | -15 | $828 | $2,001,021 | 8 | N/A | false | false |
| 22 | 21 | Me and My Umbrella | $15,402 | +5% | 54 | +7 | $285 | $374,873 | 5 | 20th Century Fox International | false | false |
| 23 | 19 | Resident Evil: Afterlife | $12,560 | -35.8% | 43 | -24 | $292 | $9,479,780 | 8 | Sony Pictures Releasing | false | false |
| 24 | 23 | Despicable Me | $8,672 | -12.6% | 27 | -11 | $321 | $13,631,940 | 14 | Universal Pictures International (UPI) | false | false |
| 25 | 11 | Piranha 3D | $7,223 | -94.2% | 21 | -119 | $343 | $899,709 | 3 | N/A | false | false |
| 26 | 24 | Cats & Dogs: The Revenge of Kitty Galore | $6,197 | -33.2% | 24 | -13 | $258 | $3,660,233 | 10 | Warner Bros. | false | false |
| 27 | 22 | So Hard to Forget | $6,003 | -53.3% | 9 | -3 | $667 | $142,894 | 4 | Europa Filmes | false | false |
| 28 | 16 | Stone | $4,098 | -90.1% | 11 | -16 | $372 | $279,806 | 3 | N/A | false | false |
| 29 | 27 | The Karate Kid | $1,453 | -72.4% | 6 | -8 | $242 | $10,142,818 | 11 | Sony Pictures Releasing | false | false |
| 30 | 29 | The Sorcerer's Apprentice | $1,163 | -33.6% | 8 | -1 | $145 | $4,974,851 | 13 | Walt Disney Pictures | false | false |
| 31 | 32 | The Well Beloved One | $951 | +20.1% | 2 | -1 | $475 | $4,919,420 | 16 | Walt Disney Pictures | false | false |
| 32 | 31 | A Prophet | $880 | -16.1% | 4 | - | $220 | $167,858 | 21 | Sony Pictures Releasing | false | false |
| 33 | 33 | The Imaginarium of Doctor Parnassus | $565 | -18.8% | 3 | -1 | $188 | $166,076 | 27 | Sony Pictures Releasing | false | false |
| 34 | 26 | Toy Story 3 | $553 | -89.6% | 6 | -12 | $92 | $24,807,192 | 21 | Walt Disney Pictures | false | false |
| 35 | 34 | 5x Favela: Now by Ourselves | $324 | -44.2% | 3 | -1 | $108 | $767,308 | 11 | Sony Pictures Releasing | false | false |
| 36 | 28 | Please Give | $193 | -94.8% | 2 | -3 | $96 | $11,973 | 2 | Sony Pictures Releasing | false | false |
| 37 | - | The Last Song | $134 | - | 4 | - | $33 | $113,647 | 22 | Walt Disney Pictures | false | false |
