Spanish 2010 Weekend 41
October 8-10, 2010
Key:New This Week
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | - | Despicable Me | $3,439,976 | - | 376 | - | $9,148 | $3,439,976 | 1 | United International Pictures |
| 2 | - | Wall Street: Money Never Sleeps | $2,242,817 | - | 338 | - | $6,635 | $2,242,817 | 1 | 20th Century Fox International |
| 3 | - | Saw VI | $1,258,106 | - | 211 | - | $5,962 | $1,258,106 | 1 | DeAPlaneta |
| 4 | 1 | Vampires Suck | $1,242,331 | -19.2% | 328 | +4 | $3,787 | $2,999,176 | 2 | 20th Century Fox International |
| 5 | 2 | Eat Pray Love | $850,714 | -33.6% | 316 | -7 | $2,692 | $5,027,039 | 3 | Sony Pictures Releasing |
| 6 | 3 | Buried | $644,434 | -28.7% | 200 | +1 | $3,222 | $1,800,365 | 2 | Warner Bros. |
| 7 | - | Letters to Juliet | $581,640 | - | 258 | - | $2,254 | $581,640 | 1 | TriPictures |
| 8 | 4 | Machete | $436,647 | -45.2% | 254 | - | $1,719 | $1,490,728 | 2 | Sony Pictures Releasing |
| 9 | 5 | Charlie St. Cloud | $426,183 | -36.1% | 258 | - | $1,651 | $1,218,373 | 2 | United International Pictures |
| 10 | 7 | The Sorcerer's Apprentice | $344,775 | -39% | 231 | -82 | $1,492 | $8,429,059 | 6 | Walt Disney Pictures |
| 11 | - | Amador | $307,113 | - | 140 | - | $2,193 | $307,113 | 1 | Alta Films |
| 12 | 8 | The American | $304,505 | -43.2% | 231 | -37 | $1,318 | $4,278,738 | 4 | United International Pictures |
| 13 | 6 | Avatar 2010 Special Edition | $278,911 | -53.9% | 132 | -110 | $2,112 | $1,719,432 | 3 | 20th Century Fox International |
| 14 | 11 | Inception | $233,643 | -29.3% | 125 | -63 | $1,869 | $22,678,377 | 10 | Warner Bros. |
| 15 | 12 | The Outlaw | $144,873 | -49.6% | 142 | -131 | $1,020 | $4,696,583 | 6 | 20th Century Fox International |
| 16 | 9 | Resident Evil: Afterlife | $121,796 | -70.8% | 143 | -202 | $851 | $7,641,270 | 5 | Sony Pictures Releasing |
| 17 | 19 | Tinker Bell and the Great Fairy Rescue | $114,465 | -22.4% | 88 | -11 | $1,300 | $1,652,162 | 6 | Walt Disney Pictures |
| 18 | 17 | You Will Meet a Tall Dark Stranger | $114,315 | -39% | 70 | -74 | $1,633 | $5,893,765 | 7 | Alta Films |
| 19 | 18 | Carancho | $109,403 | -33.3% | 52 | +1 | $2,103 | $574,759 | 3 | Golem Distribución |
| 20 | 13 | The Karate Kid | $100,433 | -61.9% | 165 | -113 | $608 | $11,598,065 | 7 | Sony Pictures Releasing |
| 21 | 10 | Step Up 3D | $99,295 | -70.5% | 107 | -154 | $927 | $2,492,034 | 4 | Walt Disney Pictures |
| 22 | 16 | Toy Story 3 | $86,883 | -53.7% | 180 | - | $482 | $33,850,010 | 12 | Walt Disney Pictures |
| 23 | 14 | The Great Vazquez | $80,523 | -68.6% | 99 | -138 | $813 | $1,067,320 | 3 | Alta Films |
| 24 | 15 | Astro Boy | $64,157 | -66.9% | 119 | -22 | $539 | $565,166 | 3 | DeAPlaneta |
| 25 | 21 | Bicicleta, cullera, poma | $58,228 | -6.5% | 24 | +7 | $2,426 | $125,781 | 2 | Sagrera TV |
| 26 | 20 | Salt | $27,451 | -65.8% | 50 | -69 | $549 | $7,994,336 | 8 | Sony Pictures Releasing |
| 27 | 23 | My Afternoons with Margueritte | $24,227 | -37.5% | 20 | -12 | $1,211 | $905,019 | 8 | Golem Distribución |
| 28 | 24 | Abel | $22,264 | -41.2% | 24 | -1 | $927 | $77,252 | 2 | Alta Films |
| 29 | - | You Again | $15,704 | - | 10 | - | $1,570 | $15,704 | 1 | Walt Disney Pictures |
| 30 | - | Blood Money | $14,827 | - | 35 | - | $423 | $14,827 | 1 | N/A |
| 31 | 25 | Undertow | $14,762 | -45.1% | 21 | -1 | $702 | $163,866 | 4 | Karma Films |
| 32 | 26 | Todo lo que tú quieras | $13,117 | -47.4% | 15 | -21 | $874 | $519,649 | 5 | Wanda Visión S.A. |
| 33 | 27 | Heaven on Earth 2010 Re-release | $12,311 | -46.1% | 14 | +3 | $879 | $35,755 | 2 | Karma Films |
| 34 | 29 | Ramona and Beezus | $11,463 | -40.7% | 13 | -7 | $881 | $131,794 | 4 | 20th Century Fox International |
| 35 | 22 | The Extraordinary Adventures of Adèle Blanc-Sec | $10,990 | -78.8% | 29 | -58 | $378 | $1,207,307 | 5 | TriPictures |
| 36 | 32 | Grown Ups | $7,880 | -44.5% | 15 | -21 | $525 | $8,489,771 | 11 | Sony Pictures Releasing |
| 37 | 33 | Bright Star | $4,274 | -69.4% | 4 | -13 | $1,068 | $399,761 | 6 | Vértigo Films |
| 38 | 31 | Shrek Forever After | $3,235 | -78.1% | 28 | -8 | $115 | $21,928,719 | 14 | Paramount Pictures International |
| 39 | 37 | Elisa K | $2,633 | -66.2% | 3 | -8 | $877 | $39,073 | 3 | Wanda Visión S.A. |
| 40 | 38 | Cats & Dogs: The Revenge of Kitty Galore | $2,038 | -69.7% | 11 | -11 | $185 | $2,685,284 | 8 | Warner Bros. |
| 41 | 28 | Going the Distance | $1,401 | -92.8% | 11 | -42 | $127 | $1,136,109 | 5 | Warner Bros. |
| 42 | 40 | Vision | $1,223 | -66.1% | 1 | -6 | $1,223 | $120,016 | 7 | Karma Films |
| 43 | 47 | Free Rainer 2010 Re-release | $927 | -23.9% | 3 | -7 | $309 | $68,359 | 7 | N/A |
| 44 | 48 | The Last Airbender | $721 | -31.4% | 2 | -3 | $360 | $9,840,134 | 10 | Paramount Pictures International |
| 45 | 45 | The Secret of Kells | $513 | -68.1% | 1 | -1 | $513 | $61,453 | 8 | Karma Films |
| 46 | 44 | Awaking from a Dream | $234 | -87.2% | 7 | -3 | $33 | $12,861 | 3 | N/A |
