| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Piranha 3D | $80,352 | - | 17 | - | $4,726 | $80,352 | 1 | N/A | true | false |
| 2 | 4 | The Spy Next Door 2010 Re-release | $39,334 | -4.2% | 15 | - | $2,622 | $167,762 | 3 | N/A | false | false |
| 3 | - | Going the Distance | $33,033 | - | 13 | - | $2,541 | $33,033 | 1 | Importadora El Rosado | true | false |
| 4 | 3 | Tinker Bell and the Great Fairy Rescue | $31,165 | -24.7% | 17 | - | $1,833 | $247,829 | 4 | Walt Disney Pictures | false | false |
| 5 | 2 | Eat Pray Love | $30,565 | -26.9% | 13 | - | $2,351 | $92,991 | 2 | Sony Pictures Releasing | false | false |
| 6 | 1 | Resident Evil: Afterlife | $29,358 | -61.7% | 23 | -24 | $1,276 | $1,001,321 | 5 | Sony Pictures Releasing | false | false |
| 7 | - | Dorothy Mills | $27,572 | - | 6 | - | $4,595 | $27,572 | 1 | N/A | true | false |
| 8 | 6 | Wall Street: Money Never Sleeps | $16,799 | -49.1% | 25 | - | $671 | $124,667 | 3 | 20th Century Fox International | false | false |
| 9 | 5 | Scar | $13,495 | -60.7% | 17 | +3 | $793 | $125,545 | 3 | N/A | false | false |
| 10 | 7 | The Expendables | $7,177 | -62.5% | 15 | -1 | $478 | $158,501 | 4 | N/A | false | false |
| 11 | 8 | Grown Ups | $6,864 | -50.6% | 5 | -7 | $1,372 | $313,915 | 6 | Sony Pictures Releasing | false | false |
| 12 | - | The Imaginarium of Doctor Parnassus | $6,232 | - | 4 | - | $1,558 | $29,452 | 22 | Sony Pictures Releasing | false | false |
| 13 | 11 | Cats & Dogs: The Revenge of Kitty Galore | $5,081 | -28.8% | 26 | - | $195 | $865,906 | 8 | Importadora El Rosado | false | false |
| 14 | 10 | Letters to Juliet | $4,637 | -59.9% | 7 | -4 | $662 | $49,598 | 3 | Venus | false | false |
| 15 | 9 | Battle for Terra | $3,810 | -68.8% | 4 | -3 | $952 | $81,752 | 4 | N/A | false | false |
| 16 | 13 | The Sorcerer's Apprentice | $2,375 | +9.5% | 13 | -1 | $182 | $827,153 | 12 | Walt Disney Pictures | false | false |
| 17 | - | An Education | $1,710 | - | 4 | - | $427 | $23,965 | 27 | Sony Pictures Releasing | false | false |
| 18 | 14 | Kick-Ass | $1,568 | +6.7% | 10 | -2 | $156 | $29,974 | 4 | United International Pictures | false | false |
| 19 | 12 | Sorority Row | $1,015 | -84% | 4 | -1 | $253 | $8,962 | 2 | N/A | false | false |
| 20 | 15 | The Karate Kid | $466 | +20.7% | 1 | -5 | $466 | $570,910 | 9 | Sony Pictures Releasing | false | false |
