| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Eat Pray Love | $3,422,817 | - | 328 | - | $10,435 | $3,634,394 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Despicable Me | $1,568,555 | -41% | 381 | -21 | $4,116 | $20,122,572 | 6 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Legend of the Guardians: The Owls of Ga'Hoole | $940,629 | -29.1% | 350 | +3 | $2,687 | $3,448,117 | 2 | Roadshow Films | false | false |
| 4 | 7 | Dinner for Schmucks | $715,702 | -30.9% | 210 | -2 | $3,408 | $2,267,072 | 2 | Paramount Pictures International | false | false |
| 5 | 4 | Wall Street: Money Never Sleeps | $685,388 | -39.5% | 254 | -29 | $2,698 | $4,961,244 | 3 | 20th Century Fox International | false | false |
| 6 | 3 | The Last Airbender | $685,236 | -42.4% | 278 | -41 | $2,464 | $9,115,976 | 4 | Paramount Pictures International | false | false |
| 7 | - | Buried | $654,346 | - | 148 | - | $4,421 | $654,346 | 1 | Icon Film Distribution | true | false |
| 8 | 5 | Diary of a Wimpy Kid | $654,171 | -38.9% | 209 | -4 | $3,130 | $4,644,274 | 3 | 20th Century Fox International | false | false |
| 9 | 6 | Cats & Dogs: The Revenge of Kitty Galore | $641,573 | -38.6% | 333 | -28 | $1,926 | $6,052,290 | 4 | Roadshow Films | false | false |
| 10 | 9 | Easy A | $500,183 | -29.8% | 147 | -16 | $3,402 | $4,988,852 | 4 | Sony Pictures Releasing | false | false |
| 11 | 8 | The Other Guys | $493,504 | -36.3% | 176 | -45 | $2,804 | $9,563,908 | 5 | Sony Pictures Releasing | false | false |
| 12 | 10 | Tomorrow, When the War Began | $467,599 | -32.1% | 188 | -52 | $2,487 | $12,467,388 | 6 | Paramount Pictures International | false | false |
| 13 | 12 | The Girl Who Played with Fire | $331,424 | -23.5% | 92 | +5 | $3,602 | $1,842,819 | 3 | Rialto Distribution | false | false |
| 14 | 13 | The Sorcerer's Apprentice | $220,524 | -48.2% | 133 | -82 | $1,658 | $4,734,716 | 5 | Walt Disney Pictures | false | false |
| 15 | 11 | Charlie St. Cloud | $194,448 | -58.2% | 157 | -7 | $1,238 | $2,025,692 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | 14 | Inception | $93,377 | -47.6% | 43 | -14 | $2,171 | $34,818,014 | 12 | Warner Bros. | false | false |
| 17 | 17 | Boy | $55,189 | -32.3% | 32 | +1 | $1,724 | $1,602,517 | 7 | Paramount Pictures International | false | false |
| 18 | 19 | The Tree | $48,317 | -28.9% | 19 | -2 | $2,543 | $200,061 | 2 | Paramount Pictures International | false | false |
| 19 | 18 | The Kids Are All Right | $45,088 | -43.6% | 36 | -7 | $1,252 | $1,538,415 | 6 | Hopscotch Films | false | false |
| 20 | 20 | Hubble | $40,838 | -21.7% | 4 | - | $10,209 | $749,975 | 22 | IMAX | false | false |
| 21 | - | Sagan 2010 Re-release | $3,700 | - | 2 | - | $1,850 | $3,700 | 1 | Hoyts Distribution | true | false |
