| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Legend of the Guardians: The Owls of Ga'Hoole | $351,431 | - | 162 | - | $2,169 | $410,180 | 1 | Warner Bros. | true | false |
| 2 | - | Tirza | $308,409 | - | 66 | - | $4,672 | $339,117 | 1 | Independent Films | true | false |
| 3 | 1 | Wall Street: Money Never Sleeps | $271,838 | -33.2% | 88 | -1 | $3,089 | $825,798 | 2 | Warner Bros. | false | false |
| 4 | 2 | Grown Ups | $247,477 | -15.5% | 60 | -2 | $4,124 | $1,599,016 | 4 | Sony Pictures Releasing | false | false |
| 5 | 3 | Resident Evil: Afterlife | $172,785 | -38.2% | 51 | +1 | $3,387 | $625,600 | 2 | Entertainment One | false | false |
| 6 | 4 | The American | $169,439 | -26.2% | 35 | - | $4,841 | $913,047 | 3 | Benelux Film Distributors | false | false |
| 7 | 5 | Inception | $156,832 | -11.8% | 86 | -10 | $1,823 | $9,188,406 | 11 | Warner Bros. | false | false |
| 8 | 7 | Going the Distance | $115,003 | -15.7% | 69 | -1 | $1,666 | $900,797 | 4 | Warner Bros. | false | false |
| 9 | 6 | Devil | $113,045 | -21.8% | 39 | -1 | $2,898 | $613,815 | 3 | Universal Pictures International (UPI) | false | false |
| 10 | 10 | Machete | $86,130 | -21.8% | 52 | +1 | $1,656 | $873,517 | 4 | Entertainment One | false | false |
| 11 | 9 | Step Up 3D | $70,104 | -38.4% | 59 | -25 | $1,188 | $4,921,589 | 9 | Independent Films | false | false |
| 12 | 8 | The Last Airbender | $64,299 | -48.1% | 63 | -18 | $1,020 | $3,674,044 | 7 | Universal Pictures International (UPI) | false | false |
| 13 | 12 | Marmaduke | $58,914 | -25.9% | 81 | -1 | $727 | $1,694,930 | 8 | Warner Bros. | false | false |
| 14 | 11 | Piranha 3D | $45,379 | -44.1% | 26 | -21 | $1,745 | $1,020,682 | 5 | A-Film Distribution | false | false |
| 15 | 13 | A Turtle's Tale: Sammy's Adventures | $34,780 | -48.8% | 66 | -18 | $526 | $1,831,728 | 9 | Universal Pictures International (UPI) | false | false |
| 16 | 17 | The Secret in Their Eyes | $31,453 | -23.3% | 14 | - | $2,246 | $480,632 | 6 | Wild Bunch Distribution | false | false |
| 17 | 15 | Toy Story 3 | $31,369 | -47.2% | 82 | -27 | $382 | $6,129,241 | 15 | Walt Disney Pictures | false | false |
| 18 | 18 | Salt | $30,569 | -22.5% | 36 | -12 | $849 | $3,150,006 | 9 | Sony Pictures Releasing | false | false |
| 19 | 14 | The Expendables | $27,413 | -55% | 47 | -29 | $583 | $2,681,429 | 7 | Benelux Film Distributors | false | false |
| 20 | 19 | I Am Love | $26,296 | -29.3% | 16 | - | $1,643 | $476,635 | 6 | Cinéart | false | false |
