| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Enthiran | $1,098,438 | - | 80 | - | $13,730 | $1,098,438 | 1 | Five Star | true | false |
| 2 | 1 | Legend of the Fist: The Return of Chen Zhen | $457,116 | -48.4% | 97 | - | $4,712 | $1,637,482 | 2 | Golden Screen Cinemas | false | false |
| 3 | - | Detective Dee: The Mystery of the Phantom Flame | $335,739 | - | 62 | - | $5,415 | $335,739 | 1 | N/A | true | false |
| 4 | 3 | Magika | $302,546 | -4.1% | 64 | - | $4,727 | $713,012 | 2 | N/A | false | false |
| 5 | 2 | Legend of the Guardians: The Owls of Ga'Hoole | $221,023 | -30.1% | 85 | - | $2,600 | $636,733 | 2 | Warner Bros. | false | false |
| 6 | - | Eat Pray Love | $129,485 | - | 25 | - | $5,179 | $129,485 | 1 | Sony Pictures Releasing | true | false |
| 7 | 4 | Wall Street: Money Never Sleeps | $92,777 | -44.9% | 35 | - | $2,650 | $321,854 | 2 | 20th Century Fox International | false | false |
| 8 | 7 | Resident Evil: Afterlife | $81,734 | +10.1% | 90 | +61 | $908 | $3,489,117 | 4 | Sony Pictures Releasing | false | false |
| 9 | - | Alpha and Omega | $74,664 | - | 33 | - | $2,262 | $74,664 | 1 | N/A | true | false |
| 10 | - | Charlie St. Cloud | $56,729 | - | 15 | - | $3,781 | $68,518 | 1 | United International Pictures | true | false |
| 11 | 6 | Devil | $39,063 | -65.3% | 25 | - | $1,562 | $519,040 | 3 | United International Pictures | false | false |
| 12 | 8 | The Hole | $38,067 | -28% | 19 | - | $2,003 | $113,452 | 2 | N/A | false | false |
| 13 | - | Blood Ties 2010 Re-release | $28,161 | - | 18 | - | $1,564 | $28,161 | 1 | N/A | true | false |
| 14 | 5 | Piranha 3D | $19,220 | -84.6% | 19 | -40 | $1,011 | $2,120,514 | 5 | N/A | false | false |
| 15 | - | Dinner for Schmucks | $11,654 | - | 15 | - | $776 | $11,654 | - | United International Pictures | - | false |
| 16 | - | Anjaana Anjaani | $6,334 | - | 2 | - | $3,167 | $6,334 | 1 | Five Star | true | false |
| 17 | 9 | Step Up 3D | $5,444 | -88% | 5 | -17 | $1,088 | $1,503,391 | 6 | N/A | false | false |
| 18 | 25 | Repo Men | $2,320 | +6,005.3% | 2 | +1 | $1,160 | $213,444 | 7 | United International Pictures | false | false |
| 19 | 16 | Grown Ups | $1,409 | -58.3% | 4 | -1 | $352 | $766,060 | 6 | Sony Pictures Releasing | false | false |
| 20 | - | Avatar 2010 Special Edition | $1,340 | - | 1 | - | $1,340 | $362,182 | 6 | 20th Century Fox International | false | false |
| 21 | 10 | Boss Engira Baskaran | $673 | -97.7% | 2 | -14 | $336 | $289,672 | 4 | Five Star | false | false |
| 22 | 13 | Cats & Dogs: The Revenge of Kitty Galore | $655 | -92.2% | 3 | -10 | $218 | $717,631 | 5 | Warner Bros. | false | false |
| 23 | 20 | The Descent: Part 2 | $551 | -63.4% | 5 | - | $110 | $243,492 | 7 | Sony Pictures Releasing | false | false |
| 24 | 11 | Old Cow Vs Tender Grass | $255 | -98% | 1 | -12 | $255 | $445,888 | 5 | N/A | false | false |
| 25 | 18 | Going the Distance | $204 | -89.8% | 2 | - | $102 | $185,832 | 5 | Warner Bros. | false | false |
| 26 | 23 | The Back-up Plan | $105 | +150% | 1 | - | $105 | $287,822 | 14 | Sony Pictures Releasing | false | false |
| 27 | 24 | Salt | $31 | -24.4% | 1 | - | $31 | $2,633,946 | 10 | Sony Pictures Releasing | false | false |
