| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Legend of the Guardians: The Owls of Ga'Hoole | $50,640 | - | 17 | - | $2,978 | $50,640 | 1 | Warner Bros. | true | false |
| 2 | 1 | The Twilight Saga: Eclipse | $31,477 | -38.5% | 13 | +3 | $2,421 | $100,292 | 2 | - | false | false |
| 3 | 2 | Resident Evil: Afterlife | $26,208 | -30.6% | 11 | -5 | $2,382 | $316,890 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | Piranha 3D | $14,856 | -10.5% | 5 | +1 | $2,971 | $39,972 | 3 | - | false | false |
| 5 | 5 | Wall Street: Money Never Sleeps | $9,752 | -9.3% | 4 | -1 | $2,438 | $24,257 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | Cats & Dogs: The Revenge of Kitty Galore | $8,421 | -34.1% | 6 | -1 | $1,403 | $263,312 | 7 | Warner Bros. | false | false |
| 7 | 11 | The Forbidden Kingdom 2010 Re-release | $5,124 | +281.8% | 2 | - | $2,562 | $9,633 | 3 | - | false | false |
| 8 | 6 | The Last Airbender | $4,974 | -53.3% | 5 | -6 | $994 | $234,430 | 6 | Paramount Pictures International | false | false |
| 9 | 9 | Grown Ups | $3,478 | -34.2% | 4 | -1 | $869 | $141,399 | 8 | Sony Pictures Releasing | false | false |
| 10 | 7 | Going the Distance | $3,136 | -48% | 3 | -1 | $1,045 | $25,694 | 3 | Warner Bros. | false | false |
| 11 | 8 | Igor | $2,559 | -55.7% | 2 | -1 | $1,279 | $19,432 | 4 | - | false | false |
| 12 | - | Paris 36 | $1,996 | - | 2 | - | $998 | $1,996 | 1 | N/A | true | false |
| 13 | 12 | Inception | $1,434 | +25.1% | 4 | +1 | $358 | $162,372 | 9 | Warner Bros. | false | false |
| 14 | - | Bangkok Dangerous | $1,236 | - | 2 | - | $618 | $1,236 | 1 | - | true | false |
| 15 | 10 | Despicable Me | $1,007 | -50.1% | 3 | -1 | $335 | $265,912 | 10 | Universal Pictures International (UPI) | false | false |
