| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Despicable Me | $2,124,481 | +2.5% | 405 | +2 | $5,245 | $11,435,360 | 4 | Universal Pictures International (UPI) | false | false |
| 2 | - | Wall Street: Money Never Sleeps | $1,651,862 | - | 283 | - | $5,836 | $1,724,481 | 1 | 20th Century Fox International | true | false |
| 3 | 1 | The Last Airbender | $1,463,873 | -43% | 341 | +10 | $4,292 | $5,238,376 | 2 | Paramount Pictures International | false | false |
| 4 | 3 | The Other Guys | $993,731 | -41.1% | 233 | -9 | $4,264 | $7,018,852 | 3 | Sony Pictures Releasing | false | false |
| 5 | 5 | Easy A | $876,848 | -21.9% | 167 | +1 | $5,250 | $2,644,026 | 2 | Sony Pictures Releasing | false | false |
| 6 | 7 | Cats & Dogs: The Revenge of Kitty Galore | $829,330 | +15.1% | 390 | +10 | $2,126 | $2,446,471 | 2 | Roadshow Films | false | false |
| 7 | 4 | Tomorrow, When the War Began | $799,343 | -31% | 261 | -61 | $3,062 | $10,030,170 | 4 | Paramount Pictures International | false | false |
| 8 | - | Diary of a Wimpy Kid | $715,330 | - | 213 | - | $3,358 | $1,202,482 | 1 | 20th Century Fox International | true | false |
| 9 | - | Charlie St. Cloud | $605,779 | - | 164 | - | $3,693 | $609,019 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 6 | The Sorcerer's Apprentice | $518,719 | -30.2% | 231 | +3 | $2,245 | $3,332,277 | 3 | Walt Disney Pictures | false | false |
| 11 | - | The Girl Who Played with Fire | $482,351 | - | 83 | - | $5,811 | $573,667 | 1 | Rialto Distribution | true | false |
| 12 | 9 | Inception | $182,043 | -45.7% | 77 | -53 | $2,364 | $33,474,791 | 10 | Warner Bros. | false | false |
| 13 | 8 | Salt | $145,639 | -63.1% | 87 | -110 | $1,674 | $11,716,603 | 6 | Sony Pictures Releasing | false | false |
| 14 | 10 | The Kids Are All Right | $93,655 | -51.2% | 49 | -12 | $1,911 | $1,273,075 | 4 | Hopscotch Films | false | false |
| 15 | 12 | Boy | $82,022 | -42.9% | 31 | -18 | $2,645 | $1,330,640 | 5 | Paramount Pictures International | false | false |
| 16 | 19 | Hubble | $41,612 | -2.8% | 6 | +4 | $6,935 | $567,550 | 20 | IMAX | false | false |
| 17 | 18 | The Infidel | $38,129 | -20.5% | 17 | +1 | $2,242 | $118,045 | 2 | Becker Film Group | false | false |
| 18 | - | Furry Vengeance | $34,315 | - | 103 | - | $333 | $92,093 | 4 | Hoyts Distribution | false | false |
| 19 | - | Ghosts of the Abyss 2010 Re-release | $32,643 | - | 1 | - | $32,643 | $4,868,708 | 20 | IMAX | false | false |
| 20 | 11 | Going the Distance | $29,092 | -81.3% | 27 | -101 | $1,077 | $2,022,192 | 4 | Warner Bros. | false | false |
