| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Resident Evil: Afterlife | $50,980 | - | 5 | - | $10,196 | $50,980 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | The Switch | $15,671 | - | 3 | - | $5,223 | $15,671 | 1 | Lionsgate | true | false |
| 3 | 1 | Machete | $8,207 | -54.6% | 3 | - | $2,735 | $35,041 | 2 | N/A | false | false |
| 4 | 2 | The Karate Kid | $7,454 | -47.5% | 4 | - | $1,863 | $25,825 | 2 | Sony Pictures Releasing | false | false |
| 5 | 3 | Cats & Dogs: The Revenge of Kitty Galore | $5,843 | -43.2% | 5 | - | $1,168 | $46,946 | 3 | Warner Bros. | false | false |
| 6 | 4 | Grown Ups | $5,484 | -35.9% | 4 | - | $1,371 | $85,469 | 4 | Sony Pictures Releasing | false | false |
| 7 | 5 | Inception | $5,062 | -29.1% | 4 | -1 | $1,265 | $266,595 | 8 | Warner Bros. | false | false |
| 8 | 7 | The Last Airbender | $4,537 | -30.1% | 3 | - | $1,512 | $145,903 | 5 | United International Pictures | false | false |
| 9 | 6 | Vampires Suck | $3,651 | -48% | 4 | - | $912 | $40,366 | 3 | 20th Century Fox International | false | false |
| 10 | 9 | Toy Story 3 | $3,063 | -43.8% | 6 | -2 | $510 | $192,828 | 9 | Walt Disney Pictures | false | false |
