| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Sorcerer's Apprentice | $63,047 | +330% | 8 | +1 | $7,880 | $82,451 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | Inception | $45,671 | +282.8% | 7 | - | $6,524 | $644,649 | 9 | Warner Bros. | false | false |
| 3 | - | Cats & Dogs: The Revenge of Kitty Galore | $24,661 | - | 6 | - | $4,110 | $24,661 | 1 | Warner Bros. | true | false |
| 4 | 7 | Predators | $17,974 | +551.2% | 5 | - | $3,594 | $30,257 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Grown Ups | $13,449 | +199.5% | 5 | - | $2,689 | $133,509 | 6 | Sony Pictures Releasing | false | false |
| 6 | 3 | The Losers | $10,892 | +129.2% | 5 | - | $2,178 | $16,870 | 2 | Warner Bros. | false | false |
| 7 | 8 | Salt | $9,497 | +253% | 3 | -1 | $3,165 | $296,132 | 8 | Sony Pictures Releasing | false | false |
| 8 | 5 | The Last Airbender | $9,200 | +182.6% | 4 | -4 | $2,300 | $187,551 | 8 | United International Pictures | false | false |
| 9 | 6 | Toy Story 3 | $5,665 | +79% | 2 | - | $2,832 | $420,954 | 13 | Walt Disney Pictures | false | false |
| 10 | 10 | Knight and Day 2010 Re-release | $5,591 | +217.1% | 1 | -2 | $5,591 | $418,090 | 11 | 20th Century Fox International | false | false |
| 11 | 9 | The Twilight Saga: Eclipse | $3,335 | +38.7% | 2 | -2 | $1,667 | $444,160 | 10 | - | false | false |
| 12 | 11 | Shrek Forever After | $1,256 | -16% | 8 | - | $157 | $253,434 | 11 | United International Pictures | false | false |
| 13 | 14 | She's Out of My League | $192 | +43.3% | 2 | -3 | $96 | $52,786 | 10 | United International Pictures | false | false |
| 14 | 13 | Robin Hood | $106 | -75% | 3 | -1 | $35 | $379,598 | 18 | United International Pictures | false | false |
