| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Step Up 3D | $355,601 | -14.8% | 71 | -3 | $5,008 | $1,713,893 | 3 | NuMetro Distribution | false | false |
| 2 | - | The Sorcerer's Apprentice | $255,858 | - | 80 | - | $3,198 | $255,858 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | The A-Team | $126,441 | -32.8% | 63 | +1 | $2,007 | $405,353 | 2 | 20th Century Fox International | false | false |
| 4 | 3 | Grown Ups | $118,352 | -10.6% | 63 | -2 | $1,878 | $1,026,368 | 4 | Sony Pictures Releasing | false | false |
| 5 | 4 | Inception | $89,372 | -20.8% | 58 | -2 | $1,540 | $1,212,870 | 5 | Warner Bros. | false | false |
| 6 | 5 | Shrek Forever After | $61,194 | -20.1% | 59 | -5 | $1,037 | $3,113,986 | 7 | United International Pictures | false | false |
| 7 | - | Avatar 2010 Special Edition | $44,325 | - | 18 | - | $2,462 | $44,325 | 1 | NuMetro Distribution | true | false |
| 8 | 6 | Cats & Dogs: The Revenge of Kitty Galore | $41,572 | -43.9% | 50 | -16 | $831 | $542,637 | 4 | Warner Bros. | false | false |
| 9 | 8 | Furry Vengeance | $29,762 | -9.9% | 35 | - | $850 | $78,909 | 2 | NuMetro Distribution | false | false |
| 10 | - | Agora | $21,949 | - | 30 | - | $731 | $21,949 | 1 | Ster-Kinekor Pictures | true | false |
| 11 | 10 | Death at a Funeral | $7,297 | -21% | 13 | -3 | $561 | $1,069,979 | 11 | Sony Pictures Releasing | false | false |
| 12 | 11 | London River 2010 Re-release | $6,631 | -19.2% | 7 | - | $947 | $19,684 | 2 | United International Pictures | false | false |
| 13 | 12 | The Unforgiving | $5,760 | -20% | 9 | -5 | $640 | $16,743 | 2 | N/A | false | false |
| 14 | 7 | Knight and Day 2010 Re-release | $4,443 | -92.9% | 57 | -11 | $77 | $1,310,803 | 6 | 20th Century Fox International | false | false |
| 15 | 14 | Toy Story 3 | $3,473 | -47.8% | 6 | -2 | $578 | $3,284,847 | 10 | Walt Disney Pictures | false | false |
| 16 | 13 | Please Give | $3,405 | -49% | 7 | - | $486 | $27,416 | 3 | Sony Pictures Releasing | false | false |
| 17 | 16 | The White Ribbon | $1,644 | -36.3% | 3 | -1 | $548 | $39,009 | 5 | United International Pictures | false | false |
| 18 | 18 | She's Out of My League | $1,269 | -42.1% | 9 | - | $141 | $656,064 | 10 | United International Pictures | false | false |
| 19 | 17 | The Boys Are Back | $771 | -65.7% | 2 | -3 | $385 | $105,322 | 8 | N/A | false | false |
| 20 | 15 | Schuks Tshabalala's Survival Guide to South Africa | $744 | -77.8% | 3 | -5 | $248 | $5,148,841 | 14 | N/A | false | false |
| 21 | 20 | Themba | $376 | -36.9% | 2 | -1 | $188 | $20,937 | 7 | N/A | false | false |
