| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Grown Ups | $3,117,633 | - | 401 | - | $7,774 | $3,117,633 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Scott Pilgrim vs. the World | $2,492,536 | - | 408 | - | $6,109 | $2,492,536 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 3 | Toy Story 3 | $2,329,394 | -28.9% | 526 | -31 | $4,428 | $105,000,800 | 6 | Walt Disney Pictures | false | false |
| 4 | 1 | The Expendables | $2,037,128 | -66.7% | 453 | - | $4,496 | $10,588,769 | 2 | Lionsgate | false | false |
| 5 | 2 | Salt | $1,503,531 | -55.3% | 413 | +67 | $3,640 | $6,809,609 | 2 | Sony Pictures Releasing | false | false |
| 6 | 4 | Piranha 3D | $1,377,101 | -33.1% | 335 | -19 | $4,110 | $5,107,469 | 2 | Entertainment Film Distributors | false | false |
| 7 | 6 | Inception | $1,085,906 | -35.1% | 339 | -80 | $3,203 | $51,396,306 | 7 | Warner Bros. | false | false |
| 8 | - | Diary of a Wimpy Kid | $1,042,596 | - | 372 | - | $2,802 | $1,042,596 | 1 | 20th Century Fox International | true | false |
| 9 | - | Avatar | $969,500 | - | 343 | - | $2,826 | $144,177,941 | 37 | 20th Century Fox International | false | false |
| 10 | 5 | Marmaduke | $911,416 | -52.8% | 457 | +80 | $1,994 | $4,564,671 | 2 | 20th Century Fox International | false | false |
| 11 | 7 | Knight and Day 2010 Re-release | $644,694 | -49.7% | 341 | -91 | $1,890 | $14,099,616 | 4 | 20th Century Fox International | false | false |
| 12 | - | The Girl Who Played with Fire | $628,974 | - | 126 | - | $4,991 | $628,974 | 1 | Momentum Pictures | true | false |
| 13 | 8 | The Last Airbender | $493,247 | -46.3% | 344 | -96 | $1,433 | $6,564,441 | 3 | Paramount Pictures International | false | false |
| 14 | 9 | Step Up 3D | $331,100 | -58.3% | 287 | -63 | $1,153 | $11,537,610 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 10 | The Sorcerer's Apprentice | $303,366 | -56% | 307 | -86 | $988 | $4,692,994 | 3 | Walt Disney Pictures | false | false |
