| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Last Airbender | $725,750 | -24.8% | 178 | -7 | $4,077 | $1,998,627 | 2 | United International Pictures | false | false |
| 2 | 2 | Inception | $218,732 | -11.8% | 98 | -14 | $2,231 | $2,503,067 | 5 | Warner Bros. | false | false |
| 3 | 3 | Cats & Dogs: The Revenge of Kitty Galore | $126,333 | -34.9% | 95 | -12 | $1,329 | $1,812,939 | 4 | Warner Bros. | false | false |
| 4 | 6 | Grown Ups | $93,134 | +2.5% | 49 | - | $1,900 | $771,639 | 5 | Sony Pictures Releasing | false | false |
| 5 | 5 | Oceans | $76,243 | -18% | 36 | +2 | $2,117 | $355,785 | 3 | Cine Colombia | false | false |
| 6 | - | Despicable Me | $70,605 | - | 76 | - | $929 | $2,609,685 | - | Universal Pictures International (UPI) | - | false |
| 7 | - | Daybreakers | $54,855 | - | 33 | - | $1,662 | $54,855 | 1 | Venus | true | false |
| 8 | - | Vampires Suck | $52,127 | - | 20 | - | $2,606 | $52,127 | 1 | 20th Century Fox International | true | false |
| 9 | 7 | Predators | $25,601 | -43.6% | 29 | -19 | $882 | $493,450 | 4 | 20th Century Fox International | false | false |
| 10 | 8 | The Sorcerer's Apprentice | $20,281 | -51.4% | 24 | -13 | $845 | $2,943,481 | 8 | Walt Disney Pictures | false | false |
| 11 | 10 | Shrek Forever After | $15,149 | -19.7% | 29 | -10 | $522 | $6,745,128 | 9 | United International Pictures | false | false |
| 12 | 9 | Halloween II | $14,405 | -56.7% | 20 | -2 | $720 | $64,520 | 2 | Cine Colombia | false | false |
| 13 | 11 | Green Zone 2010 Re-release | $14,335 | -17.3% | 19 | -1 | $754 | $90,879 | 3 | United International Pictures | false | false |
| 14 | - | Horn of Plenty 2010 Re-release | $11,959 | - | 16 | - | $747 | $11,959 | 1 | Cineplex | true | false |
| 15 | 12 | Cherry Blossoms | $4,152 | -1.4% | 4 | -1 | $1,038 | $115,023 | 9 | Cine Colombia | false | false |
| 16 | 13 | Toy Story 3 | $2,963 | -28.2% | 10 | -5 | $296 | $10,637,930 | 12 | Walt Disney Pictures | false | false |
| 17 | 15 | Two Lovers | $2,154 | -33.5% | 2 | +1 | $1,077 | $55,980 | 13 | Cine Colombia | false | false |
| 18 | - | Cloud 9 2009 Re-release | $1,254 | - | 2 | - | $627 | $51,535 | 6 | Cine Colombia | false | false |
| 19 | 14 | Salt | $1,050 | -68% | 3 | -2 | $350 | $822,230 | 7 | Sony Pictures Releasing | false | false |
