| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Last Airbender | $655,320 | -37.5% | 85 | +1 | $7,709 | $2,090,561 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | The Expendables | $514,525 | -16.8% | 91 | +3 | $5,654 | $1,545,499 | 2 | Benelux Film Distributors | false | false |
| 3 | 4 | Inception | $423,701 | +0.8% | 107 | +4 | $3,959 | $7,086,863 | 6 | Warner Bros. | false | false |
| 4 | 3 | Step Up 3D | $389,443 | -11.7% | 92 | - | $4,233 | $3,485,512 | 4 | Independent Films | false | false |
| 5 | - | Dinner for Schmucks | $256,756 | - | 49 | - | $5,239 | $298,739 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 5 | Salt | $226,366 | -15.3% | 79 | -1 | $2,865 | $2,366,839 | 4 | Sony Pictures Releasing | false | false |
| 7 | 6 | Shrek Forever After | $159,501 | +4.4% | 133 | -22 | $1,199 | $6,535,829 | 8 | Universal Pictures International (UPI) | false | false |
| 8 | - | Vampires Suck | $155,727 | - | 48 | - | $3,244 | $165,165 | 1 | Warner Bros. | true | false |
| 9 | 7 | Marmaduke | $155,184 | +7.2% | 79 | +2 | $1,964 | $1,004,202 | 3 | Warner Bros. | false | false |
| 10 | 8 | Toy Story 3 | $145,489 | +5.1% | 123 | -3 | $1,182 | $5,281,636 | 10 | Walt Disney Pictures | false | false |
| 11 | 10 | A Turtle's Tale: Sammy's Adventures | $119,212 | +20.4% | 92 | -1 | $1,295 | $1,266,475 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | - | I Am Love | $89,705 | - | 14 | - | $6,407 | $96,637 | 1 | Cinéart | true | false |
| 13 | - | The Secret in Their Eyes | $80,797 | - | 13 | - | $6,215 | $89,322 | 1 | Wild Bunch Distribution | true | false |
| 14 | 9 | The Karate Kid | $80,120 | -23.6% | 78 | -4 | $1,027 | $3,599,305 | 6 | Sony Pictures Releasing | false | false |
| 15 | 14 | Cats & Dogs: The Revenge of Kitty Galore | $67,924 | +17.1% | 88 | -5 | $771 | $1,134,722 | 5 | Warner Bros. | false | false |
| 16 | 13 | Knight and Day 2010 Re-release | $65,190 | -21.1% | 59 | -19 | $1,104 | $3,066,357 | 7 | Warner Bros. | false | false |
| 17 | 11 | The Sorcerer's Apprentice | $57,838 | -35.8% | 70 | -21 | $826 | $1,744,574 | 5 | Walt Disney Pictures | false | false |
| 18 | 12 | Sterke verhalen | $50,871 | -40.6% | 32 | - | $1,589 | $212,612 | 2 | A-Film Distribution | false | false |
| 19 | 15 | The Joneses | $26,577 | -20.5% | 16 | -1 | $1,661 | $213,616 | 3 | Benelux Film Distributors | false | false |
| 20 | - | After.Life | $21,938 | - | 8 | - | $2,742 | $34,556 | 1 | Entertainment One | true | false |
