| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inception | $25,161 | -33.7% | 7 | -1 | $3,594 | $434,066 | 5 | Warner Bros. | false | false |
| 2 | 2 | Grown Ups | $22,903 | -30.1% | 7 | - | $3,271 | $135,480 | 3 | Sony Pictures Releasing | false | false |
| 3 | 3 | Salt | $16,780 | -32.1% | 7 | - | $2,397 | $450,334 | 6 | Sony Pictures Releasing | false | false |
| 4 | 4 | The Last Airbender | $14,786 | -26.8% | 7 | -1 | $2,112 | $184,842 | 4 | United International Pictures | false | false |
| 5 | - | The Joneses | $12,227 | - | 5 | - | $2,445 | $12,227 | 1 | Italian International Film | true | false |
| 6 | - | Splice 2010 Re-release | $11,515 | - | 6 | - | $1,919 | $11,515 | 1 | N/A | true | false |
| 7 | 5 | Predators | $7,650 | -49.8% | 7 | - | $1,092 | $30,080 | 2 | 20th Century Fox International | false | false |
| 8 | 7 | Shrek Forever After | $6,938 | -26.9% | 5 | - | $1,387 | $394,073 | 7 | United International Pictures | false | false |
| 9 | 6 | Letters to Juliet | $5,200 | -54.4% | 5 | - | $1,040 | $134,614 | 5 | Jaguar Film International Distribution | false | false |
| 10 | 8 | The Fourth Kind | $4,442 | -33.4% | 3 | -2 | $1,480 | $15,319 | 2 | N/A | false | false |
| 11 | 10 | Leap Year | $3,984 | -35.5% | 3 | -1 | $1,328 | $26,996 | 3 | N/A | false | false |
| 12 | - | Undisputed 3: Redemption | $3,975 | - | 5 | - | $795 | $3,975 | 1 | N/A | true | false |
| 13 | 12 | Toy Story 3 | $3,014 | -34% | 4 | - | $753 | $286,385 | 10 | Walt Disney Pictures | false | false |
| 14 | 14 | Animal Kingdom | $2,464 | -35.4% | 1 | - | $2,464 | $9,087 | 2 | Prime Pictures | false | false |
| 15 | 13 | Lembi 8 Giga | $1,839 | -52% | 4 | -2 | $459 | $204,027 | 6 | N/A | false | false |
| 16 | 9 | The Sorcerer's Apprentice | $1,655 | -74% | 3 | -2 | $551 | $178,971 | 7 | Walt Disney Pictures | false | false |
| 17 | 16 | Knight and Day 2010 Re-release | $1,490 | -40.4% | 2 | - | $745 | $250,648 | 9 | 20th Century Fox International | false | false |
| 18 | 15 | The Grudge 3 | $856 | -71% | 3 | -1 | $285 | $16,420 | 3 | N/A | false | false |
| 19 | 18 | Al Thalasa Yeshtghilonaha | $524 | -30.8% | 1 | - | $524 | $71,233 | 7 | N/A | false | false |
| 20 | 19 | Asal | $494 | +45.3% | 2 | +1 | $247 | $118,953 | 9 | N/A | false | false |
| 21 | - | Cop Out | $433 | - | 1 | - | $433 | $42,561 | 17 | Warner Bros. | false | false |
| 22 | 17 | Prince of Persia: The Sands of Time | $403 | -59% | 2 | - | $201 | $252,106 | 14 | Walt Disney Pictures | false | false |
| 23 | 21 | The Twilight Saga: Eclipse | $117 | +28.6% | 1 | - | $117 | $427,363 | 8 | Jaguar Film International Distribution | false | false |
| 24 | 20 | Robin Hood | $59 | -35.9% | 1 | - | $59 | $333,336 | 16 | United International Pictures | false | false |
