| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Expendables | $182,789 | -55.4% | 65 | - | $2,812 | $749,835 | 2 | N/A | false | false |
| 2 | 3 | Step Up 3D | $95,318 | -12.4% | 36 | +4 | $2,647 | $281,244 | 2 | N/A | false | false |
| 3 | - | The Karate Kid | $82,373 | - | 48 | - | $1,716 | $135,032 | 1 | Sony Pictures Releasing | true | false |
| 4 | 4 | Inception | $71,367 | -22.1% | 47 | -4 | $1,518 | $1,220,450 | 5 | Warner Bros. | false | false |
| 5 | - | A Turtle's Tale: Sammy's Adventures | $67,602 | - | 40 | - | $1,690 | $67,602 | 1 | N/A | true | false |
| 6 | 2 | Grown Ups | $54,588 | -56% | 48 | -2 | $1,137 | $580,064 | 3 | Sony Pictures Releasing | false | false |
| 7 | 5 | Salt | $33,678 | -50.1% | 70 | -5 | $481 | $1,160,975 | 4 | Sony Pictures Releasing | false | false |
| 8 | 6 | Cats & Dogs: The Revenge of Kitty Galore | $16,841 | -66.7% | 52 | -2 | $323 | $451,049 | 4 | Warner Bros. | false | false |
| 9 | 7 | The Sorcerer's Apprentice | $15,775 | -63.6% | 52 | -28 | $303 | $1,184,968 | 5 | Walt Disney Pictures | false | false |
| 10 | 9 | Tinker Bell and the Great Fairy Rescue | $13,152 | -39.4% | 35 | -1 | $375 | $44,206 | 2 | Walt Disney Pictures | false | false |
| 11 | 8 | Despicable Me | $12,227 | -55.1% | 29 | -18 | $421 | $1,075,980 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | The Last Airbender | $4,714 | -46.4% | 26 | -9 | $181 | $1,745,724 | 7 | Paramount Pictures International | false | false |
| 13 | 11 | Predators | $1,892 | -63.7% | 8 | -10 | $236 | $393,491 | 7 | 20th Century Fox International | false | false |
| 14 | 13 | Shrek Forever After | $1,678 | -22.1% | 1 | -1 | $1,678 | $4,019,941 | 14 | Paramount Pictures International | false | false |
| 15 | 12 | The Twilight Saga: Eclipse | $1,044 | -70.4% | 5 | -12 | $208 | $1,677,422 | 7 | N/A | false | false |
| 16 | 16 | Avatar | $646 | -18.2% | 2 | - | $323 | $8,297,804 | 36 | 20th Century Fox International | false | false |
| 17 | 15 | Get Him to the Greek | $245 | -69.5% | 1 | -1 | $245 | $160,453 | 10 | Universal Pictures International (UPI) | false | false |
| 18 | 14 | Knight and Day 2010 Re-release | $105 | -90.8% | 2 | -3 | $52 | $604,705 | 9 | 20th Century Fox International | false | false |
| 19 | 17 | Toy Story 3 | $44 | -85% | 1 | -4 | $44 | $665,676 | 9 | Walt Disney Pictures | false | false |
