| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Salt | $52,774 | - | 7 | - | $7,539 | $52,774 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Inception | $24,253 | -33.5% | 5 | - | $4,850 | $406,186 | 4 | Warner Bros. | false | false |
| 3 | - | The Last Airbender | $19,389 | - | 5 | - | $3,877 | $32,962 | 1 | United International Pictures | true | false |
| 4 | 3 | Shrek Forever After | $14,993 | -6.7% | 9 | -1 | $1,665 | $272,011 | 5 | United International Pictures | false | false |
| 5 | 4 | The Karate Kid | $11,446 | -24% | 4 | -2 | $2,861 | $112,117 | 3 | Sony Pictures Releasing | false | false |
| 6 | 2 | The Sorcerer's Apprentice | $10,963 | -45.3% | 5 | -1 | $2,192 | $71,652 | 2 | Walt Disney Pictures | false | false |
| 7 | 5 | Toy Story 3 | $5,997 | +19.6% | 4 | - | $1,499 | $414,280 | 9 | Walt Disney Pictures | false | false |
| 8 | 11 | The Ugly Duckling and Me! | $3,308 | +94% | 4 | - | $827 | $6,147 | 2 | N/A | false | false |
| 9 | 6 | Knight and Day 2010 Re-release | $1,934 | -58.6% | 3 | - | $644 | $110,778 | 6 | 20th Century Fox International | false | false |
| 10 | 9 | Grown Ups | $1,418 | -37.6% | 1 | - | $1,418 | $134,585 | 8 | Sony Pictures Releasing | false | false |
| 11 | 12 | Babies | $1,394 | +6.7% | 1 | - | $1,394 | $23,180 | 4 | N/A | false | false |
| 12 | 7 | 22 Bullets | $1,073 | -71.1% | 1 | - | $1,073 | $10,222 | 2 | N/A | false | false |
| 13 | 8 | Predators | $956 | -63.6% | 2 | -2 | $478 | $67,080 | 5 | 20th Century Fox International | false | false |
| 14 | 10 | The Twilight Saga: Eclipse | $569 | -67.1% | 1 | - | $569 | $155,784 | 7 | N/A | false | false |
| 15 | 14 | Sex and the City 2 | $472 | +14.6% | 1 | - | $472 | $245,935 | 11 | Warner Bros. | false | false |
